Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

New class of drug holds potential to help patients with treatment-resistant cancers

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies.

10 Apr 2018

Validating the Diagnosis of Depression

It’s very difficult to diagnose depression. With depression, you can't open the brain to find answers, and the chemistry of the brain is separate from the chemistry of the body.

From Pittcon 10 Apr 2018

Insilico to present recent advances in AI for aging biomarkers and age management research

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, biomarker development and aging research, is pleased to announce the presentation of its Director of Drug Discovery, Dr. Ivan Ozerov, at the 24th Clinical Applications for Age Management Medicine Conference, April 27, 2018, organized by Age Management Medicine Group.

6 Apr 2018

New blood test can detect early indicators of Alzheimer's disease

There is, as yet, no cure for Alzheimer's disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for an effective intervention.

6 Apr 2018

Researchers find potential remedy that could restore hearing for millions

Researchers at USC and Harvard have developed a new approach to repair cells deep inside the ear -- a potential remedy that could restore hearing for millions of elderly people and others who suffer hearing loss.

5 Apr 2018

Pittcon 2018 ends in Orlando with $23 million economic impact

Pittcon 2018, the 69th Conference and Exposition for Analytical Chemistry and Applied Spectroscopy, ended on March 1, in Orlando, Florida with an economic impact to the city estimated at $23 million. This global event brought together approximately 11,415 conferees and exhibitor personnel (official numbers to be released at the end of March).

From Pittcon 23 Mar 2018

Platypus milk may help combat antibiotic resistance

According to researchers, milk obtained from the duck-billed platypus could soon be used to fight antibiotic resistance. The new study report was published in the journal Structural Biology Communications.

18 Mar 2018

International research consortium identifies 22 new genetic risk factors for stroke

An international research consortium studying 520,000 individuals from around the world has identified 22 new genetic risk factors for stroke, thus tripling the number of gene regions known to affect stroke risk.

13 Mar 2018

ANU research explores way to reduce unwanted side-effects of common drugs

New research from The Australian National University has drilled down to the molecular level to find similarities across six pharmaceutical drugs used in pain relief, dentist anesthetic, and treatment of epilepsy, in a bid to find a way to reduce unwanted side-effects.

27 Feb 2018

Carbon monoxide enhances efficacy of antibiotic against stomach infection

Carbon monoxide can improve the effectiveness of antibiotics, making bacteria more sensitive to antibiotic medication, according to a study led by Georgia State University.

22 Feb 2018

'Click chemistry' approach may improve disease-fighting properties of drugs

Researchers at The Scripps Research Institute have developed a quick and easy way to simultaneously modify dozens of drugs or molecules to improve their disease-fighting properties.

19 Feb 2018

Porvair Sciences extends range of impact support mats to protect microplates during centrifugation

Porvair Sciences has extended its range of silicone impact support mats to protect deep well microplates when they are being centrifuged.

From Porvair Sciences Limited 14 Feb 2018

New tool measures cell strength 100 times faster than current technologies

Engineers, doctors and scientists at UCLA and Rutgers University have developed a tool that measures the physical strength of individual cells 100 times faster than current technologies.

12 Feb 2018

Researchers create new device to accelerate, improve accuracy of drug screening process

McMaster University engineers have devised a way to make testing for new drugs more efficient and affordable, and reduce the time for helpful medications to reach the public.

9 Feb 2018

Biomedical engineers develop miniature self-sealing wound model

Biomedical engineers have developed a miniature self-sealing model system for studying bleeding and the clotting of wounds. The researchers envision the device as a drug discovery platform and potential diagnostic tool.

8 Feb 2018

First drug-candidate compounds discovered using AI licensed for development

Insilico Medicine, Inc., a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, announces that Juvenescence.AI, its joint venture with Juvenescence Limited, has licensed its first compound family for clinical development.

7 Feb 2018

Previously discarded antibiotic compounds could become life-saving drugs

Researchers are re-examining antibacterial compounds to see whether they could hold the key to fighting drug-resistant infections.

7 Feb 2018

Open Pharma drug discovery project aims to develop new treatments for mycetoma

The MycetOS project was launched today by the University of Sydney, Erasmus MC, and the Drugs for Neglected Diseases initiative to use an Open Pharma approach to discover compounds that could lead to new treatments for patients suffering from fungal mycetoma (eumycetoma), a devastating disease for which current treatments are ineffective, expensive, and toxic.

6 Feb 2018

Corning and CytoSMART collaborate to simplify cell counting in laboratories

Corning Incorporated and CytoSMART Technologies BV today announced an agreement that will simplify mammalian cell counting in laboratories around the world. Cell counting is a critical step in subcultivation in the cell culture workflow.

6 Feb 2018

Researchers identify promising new drug target for Ewing sarcoma

Screening a class of recently-developed drug compounds -- so-called "CDK inhibitors" capable of blocking CDK7/12/13 proteins -- against hundreds of different human cancer cell lines, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that CDK12 inhibitors pack a particularly lethal punch to Ewing sarcoma, a rare cancer typically affecting children and young adults.

25 Jan 2018