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New malaria vaccine strain shows promise in preclinical trials

In a report published on March 21, 2024 in EMBO Molecular Medicine (A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion) investigators at Seattle Children's Research Institute and Sanaria Inc. describe the development of a whole malaria parasite vaccine strain that infects the liver, develops to the late liver stage, and then gets completely stuck and cannot burst out of the liver to cause symptomatic blood infection.

2 Apr 2024

Cardiovascular risk can rise sharply after women go through menopause

Study shows women quickly catch up to men in terms of cardiovascular risk; underscores the need for increased awareness and screening.

2 Apr 2024

Revolutionizing brain tumor treatment: the rise of AI in neuro-oncology

The current state of knowledge about the role of artificial intelligence (AI) in the diagnosis, treatment, and prognosis of brain tumors.

2 Apr 2024

Rare variants in the YKT6 gene cause new neurological disorder, study finds

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

1 Apr 2024

AI deciphers city designs that could cut heart disease rates

AI models analyzing over half a million Google Street View images uncover urban features linked to coronary heart disease, offering insights for city design to lower disease rates.

1 Apr 2024

Climate change boosts infectious disease spread, hits the vulnerable hardest

Climate change is intensifying the spread of vector, water, and food-borne infections, disproportionately affecting vulnerable populations due to enhanced pathogen transmission in altered environmental conditions.

1 Apr 2024

New immunotherapy strategy potentially lays the groundwork for treating autoimmune diseases

Mayo Clinic scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune diseases.

1 Apr 2024

Ketogenic diet can be a powerful aid in treating mental illness

For people living with serious mental illness like schizophrenia or bipolar disorder, standard treatment with antipsychotic medications can be a double-edged sword.

1 Apr 2024

Childhood BMI tied to higher blood pressure in middle age

Children and teenagers living with overweight or obesity are more likely to have high blood pressure as adults (aged 50-64 years), suggesting the processes behind the condition could begin as early as childhood, suggests new research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May).

1 Apr 2024

Tuberculosis linked to increased risk of cancer, study finds

A population-wide observational study to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows an association between tuberculosis (TB) and cancer, with those with current or previous TB more likely to have a diagnosis of a variety of cancers, including lung, blood, gynaecological and colorectal cancers.

1 Apr 2024

Research suggests booster doses may be necessary for monkeypox immunity

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that even in men who receives two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.

1 Apr 2024

Four years after shelter-in-place, covid-19 misinformation persists

From spring break parties to Mardi Gras, many people remember the last major “normal” thing they did before the novel coronavirus pandemic dawned, forcing governments worldwide to issue stay-at-home advisories and shutdowns.

1 Apr 2024

Heavy drinkers who cut back see major heart health benefits, study finds

Study shows that heavy drinkers who reduced their alcohol intake experienced a significantly lower risk of major adverse cardiovascular events, underscoring the potential benefits of alcohol reduction on heart health.

31 Mar 2024

Space travel alters human vascular cell function, study finds

Study investigates the transcriptomic changes in human vascular smooth muscle cells exposed to spaceflight, revealing significant alterations in gene expression affecting cellular function and phenotype.

31 Mar 2024

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

31 Mar 2024

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Researchers from Lund University in Sweden have identified distinct molecular signatures associated with the clinical signs of sepsis that could provide more accurate diagnosis and prognosis of sepsis, as well as help to target specific therapies at patients who would benefit most, according to new research being presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April).

30 Mar 2024

WHO calls for urgent action on rising neurological conditions worldwide

A major new study released by The Lancet Neurology shows that, in 2021, more than 3 billion people worldwide were living with a neurological condition.

30 Mar 2024

Unlocking clotting mechanisms in caterpillar hemolymph for medical use

Blood is a remarkable material: it must remain fluid inside blood vessels, yet clot as quickly as possible outside them, to stop bleeding. The chemical cascade that makes this possible is well understood for vertebrate blood.

30 Mar 2024

Innovative tool could safeguard cancer patients from chemotherapy-induced kidney damage

Using patient data from six major U.S. cancer centers, Brigham researchers and collaborators developed a risk prediction model for moderate-to-severe kidney injury after receiving the chemotherapy drug cisplatin in the largest, first generalizable study of its kind.

30 Mar 2024

Vegan diet benefits individuals with type 1 diabetes, study shows

A low-fat vegan diet rich in fruits, vegetables, grains, and beans reduces insulin needs and improves insulin sensitivity and glycemic control in people with type 1 diabetes, according to a first-of-its-kind study by the Physicians Committee for Responsible Medicine published in Clinical Diabetes.

29 Mar 2024