Immune System News and Research

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New EV platform could help streamline the development and delivery of vaccines worldwide

To many, EV stands for "electric vehicle." To researchers at Harvard University and the University of Nebraska–Lincoln, it's shorthand for another vehicle -; this one nanoscopic -; that might help streamline the development and delivery of vaccines worldwide.

30 Jan 2023

New research changes the paradigm of how people think about graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

30 Jan 2023

Study shows how arthritis affects people's working lives

The typical person living with arthritis in the UK is 20% less likely to be in work than their equivalent without the condition, new research shows.

30 Jan 2023

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer’s recurrence.

30 Jan 2023

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Under the supervision of four professors from the UMCG departments of Gastroenterology and Hepatology and Pathology and Medical Biology, Bourgonje conducted doctoral research on the predictive value of biomarkers for inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis.

29 Jan 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Treatment to boost white blood cells may benefit patients with glioblastoma

A new study led by Washington University School of Medicine in St. Louis reveals at least one cause of low white blood cell counts in patients treated for glioblastoma and demonstrates a potential treatment strategy that improves survival in mice.

27 Jan 2023

Studying the HIV response for pandemic preparedness

Researchers assessed the impact of utilizing the human immunodeficiency virus (HIV) response in improving pandemic preparedness.

27 Jan 2023

Researchers identify an unexpected driver of cancer immunotherapy resistance

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signaling on tumor-killing CD8+ T cells.

27 Jan 2023

Children’s immune systems do not develop ‘adaptive’ memory to protect against second time SARS-CoV-2 infection

Children have largely avoided severe COVID-19 symptoms because they have a strong initial 'innate' immune reaction that quickly defeats the virus.

26 Jan 2023

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

26 Jan 2023

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

Researchers discover the impact of microRNA on inflammation in lupus

A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice.

26 Jan 2023

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

25 Jan 2023

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans."

25 Jan 2023

Study provides an estimate of people in the United States with VEXAS syndrome

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Immune System News and Research

New EV platform could help streamline the development and delivery of vaccines worldwide

New research changes the paradigm of how people think about graft-versus-host disease

Study shows how arthritis affects people's working lives

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Activated neutrophils can become potent cancer fighters

Treatment to boost white blood cells may benefit patients with glioblastoma

Studying the HIV response for pandemic preparedness

Researchers identify an unexpected driver of cancer immunotherapy resistance

Children’s immune systems do not develop ‘adaptive’ memory to protect against second time SARS-CoV-2 infection

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Researchers discover the impact of microRNA on inflammation in lupus

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

Study provides an estimate of people in the United States with VEXAS syndrome

Transient gut infection influences hosts’ adaptation to nutrient restriction

CHLA launches first clinical trial for Down syndrome regression disorder with $5.3 million NIH grant

Healthy gene found in centenarians can reverse the decline of heart performance in older people

Study reviews mechanistic data on new methods of allergy prevention and treatment

Immunology eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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