Aortic Stenosis News and Research

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Medtronic’s Evolut valve reduces dysfunction, improves quality of life in women with severe aortic stenos

Medtronic, the global leader in healthcare technology, today announced new data from the largest head-to-head comparative trial of transfemoral transcatheter aortic valve replacement (TAVR), the SMall Annuli Randomized To Evolut or SAPIEN (SMART) Trial, looking exclusively at women.

20 May 2024

Study shows comparable outcomes for TAVR and SAVR in aortic valve replacement

A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart-;transcatheter aortic valve replacement (TAVR)-;and surgical aortic valve replacement (SAVR).

15 May 2024

SMART study shows hemodynamic benefits of self-expanding valves in aortic stenosis patients

Additional analysis from the SMall Annuli Randomized To Evolut or SAPIEN (SMART) study demonstrated clinical non-inferiority of self-expanding valves (SEV) versus balloon-expandable valves (BEV) in aortic stenosis patients undergoing transcatheter aortic valve replacement (TAVR) and confirmed valve performance superiority over time based on hemodynamics.

3 May 2024

New transcatheter heart valve shows promise in treating aortic stenosis

Recent findings from a study on a transcatheter heart valve (THV) system, which includes a new class of transcatheter aortic valve, showed positive results in the device's ability to function as a healthy and natural aortic valve in patients with aortic stenosis (AS).

3 May 2024

TAVR demonstrates lower risk and improved outcomes compared to SAVR in low-risk patients

Transcatheter aortic valve replacement (TAVR) was found to bring no increased risks and was associated with substantial decreased rates of death or stroke at one year in low-risk patients, compared with surgical aortic valve replacement (SAVR), according to findings presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Age-based comparison of TAVR outcomes in Vietnamese patients with aortic stenosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. The increasing number of elderly patients with severe aortic valve stenosis undergoing transcatheter aortic valve replacement (TAVR) has prompted concerns regarding their clinical outcomes compared with the younger population.

5 Mar 2024

Many young patients choose TAVR despite better long-term survival with surgery

Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis, many hospitals are still opting for a nonsurgical approach in patients under 60-;possibly with poorer survival rates.

29 Jan 2024

American Heart Association Merit Award fuels three research avenues to tackle heart disease

A physician-scientist from Massachusetts researching whether chemicals naturally occurring in foods could help treat heart disease, a genetics expert from Pennsylvania exploring the molecular mechanisms of lipid metabolism and cardiovascular diseases and a California-based professor of cardiovascular medicine studying how vaping impacts the development of abdominal aortic aneurysms are the most recent American Heart Association Merit Award recipients.

9 Jan 2024

Calcium channel blockers: A new hope for pregnant women with vasospastic angina

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a calcium channel blocker, according to a case published in a special Cardio-Obstetrics issue of JACC: Case Reports.

6 Dec 2023

New bedside cardiac assessment curriculum focuses on patient-centered learning

Bedside cardiac assessment (BCA) involves gathering a patient's medical history, performing a physical examination, and determining the need for diagnostic testing.

31 Oct 2023

3D modeling reveals cause of balloon rupture during TAVR in patients with bicuspid aortic valves

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Balloon rupture during transcatheter aortic valve replacement (TAVR) is a rare but serious complication.

25 Oct 2023

Study shows TAVR as a good alternative to open-heart surgery in younger patients with aortic stenosis

Patients with a dysfunctional aortic heart valve who received a new, prosthetic valve through a minimally invasive procedure had similar outcomes at five years as those who underwent open-heart surgery, a new study shows.

24 Oct 2023

New calculation may help identify aortic stenosis patients at higher risk of death

Mayo Clinic researchers have developed a calculation that can help identify moderate aortic stenosis patients at higher risk of dying from the condition.

5 Oct 2023

New study reveals inequalities in the provision of heart valve replacement surgery

There are striking inequalities in the provision of major (aortic) heart valve replacement surgery across England, with women, Black and Asian people, and those living in areas of deprivation much less likely to receive the life-saving procedure, suggests a large data analysis, published in the open access journal Open Heart.

4 Oct 2023

Physician-assessed aortic stenosis severity correlates with clinical outcomes, study shows

The diagnosed severity of aortic stenosis strongly correlates with clinical outcomes, new Kaiser Permanente research shows.

5 Sep 2023

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Researchers evaluated the tolerability, safety, pharmacodynamics, and pharmacokinetic properties of muvalaplin.

30 Aug 2023

TAVR for aortic regurgitation: Moving beyond "off-label" use

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transcatheter aortic valve replacement (TAVR) is currently a widely used option for patients with severe symptomatic aortic stenosis with high to low surgical risk.

13 Jul 2023