Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Men face higher risk of diabetes complications than women, study finds

Men are at greater risk than women of the major health effects of diabetes (types 1 and 2), suggests a long term study published online in the Journal of Epidemiology & Community Health.

16 May 2024

Cardiovascular burden of TTR gene variant among Black carriers across mid to late-life

The key contribution of this study was to provide more accurate estimates of cardiovascular risk across mid to late life, compared to previously existing analyses.

15 May 2024

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

People with a common heart condition were able to use significantly more oxygen while exercising after taking an investigational drug in an international clinical trial, according to a study published today in the New England Journal of Medicine.

14 May 2024

Aficamten shows promise in enhancing exercise capacity in patients with hypertrophic cardiomyopathy

Even though mortality and hospitalization rates have improved, the quality of life for those living with hypertrophic cardiomyopathy (HCM) can be compromised with limiting symptoms such as exertional dyspnoea and decreased exercise capacity.

13 May 2024

Semaglutide improves heart failure symptoms and reduces loop diuretic dose

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction (HFpEF) regardless of diuretic use, according to late breaking research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

New clinical guideline released for effectively managing individuals with hypertrophic cardiomyopathy

The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM).

8 May 2024

Breakthrough implantable cardiac pump offers hope for children awaiting heart transplants

A small, implantable cardiac pump that could help children await heart transplants at home, not in the hospital, has performed well in the first stage of human testing.

7 May 2024

Breakthrough imaging technique enhances evaluation of cardiac conditions and chest pain

A new imaging technique tested in patients could improve the evaluation of cardiac conditions and undiagnosed chest pain.

6 May 2024

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

The first U.S. heart patient involved in a study for a new gene-editing therapy directly infused inside the body has successfully been enrolled at MedStar Washington Hospital Center.

6 May 2024

Brief episode of anger may negatively impact blood vessels' ability to relax

A brief episode of anger triggered by remembering past experiences may negatively impact the blood vessels' ability to relax, which is essential for proper blood flow, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

1 May 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

Surgeons at NYU Langone Health performed the first combined mechanical heart pump and gene-edited pig kidney transplant surgery.

24 Apr 2024

New models improve heart disease risk prediction, especially for women

When it comes to matters of the heart, cardiovascular disease in women is underdiagnosed compared to men. A popular scoring system used to estimate how likely a person is to develop a cardiovascular disease within the next 10 years is the Framingham Risk Score. It is based on factors including age, sex, cholesterol levels, and blood pressure.

23 Apr 2024

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Dilated cardiomyopathy is the most frequent cause of heart failure in young people and is the leading cause of heart transplantation. In this disease, the heart enlarges and reduces its capacity to pump blood. People with dilated cardiomyopathy are at high risk for arrhythmias and sudden death.

22 Apr 2024

Lifetime risk of atrial fibrillation rises to nearly 31% in recent decade

The risk of both AF and its complications in a Danish national cohort, beginning from the age of 45 years.

17 Apr 2024

Chronic low-level inflammation may be a contributor to both depression and heart disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital have found.

8 Apr 2024

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

The investigational drug ninerafaxstat showed a good tolerability and safety profile, along with evidence of improvements in symptoms and exercise capacity among people with nonobstructive hypertrophic cardiomyopathy (HCM), according to results of a 12-week phase 2 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment in patients who were not taking SGLT2 inhibitors or GLP-1 RAs, which are antidiabetic medications that also have benefits for the heart.

8 Apr 2024

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

The first randomized trial to investigate preventive ablation of a potential arrhythmogenic substrate associated with coronary chronic total occlusion (CTO) in patients at high risk of ventricular arrhythmias (VAs) reduces the risk of appropriate implantable cardioverter-defibrillator (ICD) therapy and unplanned hospitalization in patients with no previously recorded VAs.

8 Apr 2024

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

A new technology using ultralow temperature cryoablation (ULTC) has eliminated clinical ventricular tachycardia (VT) in 94% of patients. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).

8 Apr 2024

Cardiomyopathy News and Research

Further Reading

Men face higher risk of diabetes complications than women, study finds

Cardiovascular burden of TTR gene variant among Black carriers across mid to late-life

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

Aficamten shows promise in enhancing exercise capacity in patients with hypertrophic cardiomyopathy

Semaglutide improves heart failure symptoms and reduces loop diuretic dose

New clinical guideline released for effectively managing individuals with hypertrophic cardiomyopathy

Breakthrough implantable cardiac pump offers hope for children awaiting heart transplants

Breakthrough imaging technique enhances evaluation of cardiac conditions and chest pain

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

Brief episode of anger may negatively impact blood vessels' ability to relax

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

New models improve heart disease risk prediction, especially for women

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Lifetime risk of atrial fibrillation rises to nearly 31% in recent decade

Chronic low-level inflammation may be a contributor to both depression and heart disease

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

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