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Parkinson's disease breakthrough

Brandeis scientists have made groundbreaking advances in understanding how the regulations of a novel gene during the cell cycle can lead to a rare familial case of the early onset of Parkinson's disease.

5 Jun 2004

New generation drug therapy targets the individual

The days of ‘one size fits all’ medicines may soon be a thing of the past for people undergoing radical drug therapies for chronic or serious illnesses.

5 Jun 2004

Genes that allow nerve cells to communicate may have come from bacteria eons ago

Some of the genes that allow nerve cells and some other types of cells to send elaborate chemical messages to each other appear to have been transferred to animals or their immediate ancestors from bacteria eons ago.

2 Jun 2004

Research laboratory at the forefront of the science of metabolomics

A new $1.8 million research laboratory will catapult Iowa State University to the forefront of the science of metabolomics.

2 Jun 2004

How we pass our genes to our children

An Oxford-led team of researchers has found out more about what happens during recombination, the process by which the genetic information you inherited from your mother and father is mixed up to make a sex chromosome to pass on to your offspring.

1 Jun 2004

Human Genome Sciences has begun dosing patients with chronic hep C drug

Human Genome Sciences, Inc. announced today that it has begun dosing patients in a Phase 2 clinical trial of Albuferon™ (albumin-interferon alpha) in patients with chronic hepatitis C who are naïve to interferon-alpha treatments.

27 May 2004

Computer program to predict where DNA molecules will pop open when twisted

Biologists are used to thinking about DNA sequences as a string of letters (A, C, G, T) that happens to be arranged in an elegant double helix. But DNA also has mechanical properties that affect how genes are turned on or off, say researchers at the UC Davis Genome Center.

24 May 2004

Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals

Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals. The discovery was made by applying the latest laboratory methods to a strain of mice restored from embryos frozen since the early 70s.

23 May 2004

Genome research sheds light on Bardet-Biedl syndrome

By comparing the genomes of an alga, a weed and humans, a team of researchers has identified a new gene behind Bardet-Biedl syndrome (BBS), a complex condition marked by learning disabilities, vision loss and obesity.

21 May 2004

Scientists believe that the dog genome holds a wealth of information that will benefit human health

Recently completed genetic analysis reveals that half of the more than 300 inherited canine disorders — including a number of cancers — resemble specific diseases of man; many scientists believe that the dog genome holds a wealth of information that will benefit human health.

20 May 2004

Protein that appears to play a key role in Alzheimer's disease

A protein that allows human cancer to resist multiple anticancer drugs also appears to play a key role in Alzheimer's disease, according to research conducted at Fox Chase Cancer Center. The protein, active in brain tissue, could be a target for new drugs to treat patients with Alzheimer's.

20 May 2004

Scientists have sped up a common jumping gene found in the human genome

Johns Hopkins scientists have transformed a common "jumping gene" found in the human genome into one that moves hundreds of times more often than normal in mouse and human cells.

20 May 2004

Scientists have taken the first steps towards producing a sustainable and pure source of the healthy fats found in oily fish

Eating such fish is encouraged as part of a healthy diet as their oils are rich in very long chain polyunsaturated fatty acids (VLCPUFAs). However, views on the health-promoting nature of VLCPUFAs have to be balanced against the marine pollution that can cause fish, and the oils extracted from them, to be contaminated with heavy metals and dioxins, and the fact that fish stocks are in global decline.

20 May 2004

Genome Quebec Innovation Centre has announced the signing of a service agreement with GenoMed

The McGill University and Genome Quebec Innovation Centre has announced the signing of a service agreement with GenoMed, a US company located in St. Louis, Missouri that specializes in using genomics to practice better medicine.

19 May 2004

National Cancer Institute (NCI) purchases Starbridge Hypercomputer® to accelerate genome data research

Starbridge Systems announced today that the National Cancer Institute's Advanced Biomedical Computing Center (ABCC) in Frederick, MD, recently purchased a Starbridge Hypercomputer®, the first high-end reconfigurable computer acquired for bioscience research.

19 May 2004

Want a new type of man? Maybe less brawn and more brains?

A new version of the human male is a distinct possibility, given the genetic erosion of the “junk” sex-determining chromosome that makes men male.

17 May 2004

Vitamin discovery offers clues for cancer chemotherapy

NH-Dartmouth Medical School cancer researchers, in a fusion of biochemistry and genetics, have discovered a new vitamin in a molecular pathway central to such vital processes as gene regulation, metabolism and aging. And, they found that milk contains this nutrient.

15 May 2004

3 people with drug-resistant HIV become first to undergo a new form of gene therapy

The idea is to use a modified form of HIV to deliver an "antisense" gene to the immune cells that HIV infects. This is integrated into the cells' genome, and stays there until a cell is infected. Then it is switched on, and produces RNA complementary to the "sense" RNA encoding a viral protein. In theory, the RNAs should bind together, blocking viral replication.

14 May 2004

Biochip technology to revolutionise the pharmaceutical industry

Advancements in biotechnology have culminated in its integration with semiconductor technologies such as micro-electromechanical systems, resulting in the evolution of biochips. Biochips provide pharma companies with sophisticated tools for speedy development of drugs and accurate diagnosis and understanding of biological mechanisms.

13 May 2004

Faster technique for extracting DNA

A computer scientist at Washington University in St. Louis has developed a novel technique to extract more DNA from a single sequence reaction than is normally possible, reducing both cost and time of the sequencing process.

10 May 2004