The new Postnova AF2000 MultiFlow FFF Series was invented to become the first professional modular Flow FFF platform available. It is completely integrated by the NovaFFF single software platform which runs the entire system from autosampler to detectors.
The AF2000 Series incorporates the combined solid know-how and the technologies from three decades of leadership in FFF.
Due to its unique design, the AF2000 MultiFlow platform offers more flexibility, higher robustness and better performance than any system before.
The technology sets a new standard in the area of Flow FFF and marks a real break-through in FFF science and therefore naturally has become the leading Flow FFF solution for many scientists around the world.
Universal Flexible Separator
The AF2000 Series platform is based on the Flow FFF principle, using a crossflow field as driving force for the separation. The samples which are affected by this field are separated by their Dynamic Diffusion on the basis of the molar mass or particle size.
The AF2000 can be run with different eluents, at various temperature conditions and is able to employ various channel dimensions and principles.
The same system can be used for running planar Asymmetric Flow FFF (AF4) channels or circular HollowFiber Flow FFF (HF5) channels.
Therefore the AF2000 MultiFlow can be easily used for separation of a broad range of different samples from the area of Biopharmaceuticals, Food-Agro-Cosmetics, Environmental, Chemicals and Nanotechnology.
The MultiFlow FFF is ideal for the characterization of proteins, antibodies, aggregates, vaccines, liposomes, nanoparticles and natural or synthetic macromolecules. Because of its great flexibility, the AF2000 MultiFlow FFF can be employed as a Universal Separator for many kind of analyte systems and is a secure investment also for new upcoming samples and future project demands.
AF2000 AT - Standard Ambient Temp Flow FFF
The AF2000 AT is a non-temperature controlled economical Flow FFF which is ideal for the use in general level research in universities, companies and public scientific centers.
It is available as aqueous metal-free, stainless steel and multisolvent version and can be run with a broad range of aqueous and organic solvents. Planar Asymmetric Flow FFF (AF4) and circular HollowFiber Flow FFF (HF5) channels can used at the same time.
Various detection principles, such as UV-Absorbance (UV), Refractive Index (RI), Multi-Angle Light Scattering (MALS), Dynamic Light Scattering (DLS) and Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) can be coupled easily.
AF2000 MT - Advanced Mid Temp Flow FFF
The AF2000 MT is a temperature controlled advanced Flow FFF system, which is ideal for the use in higher level research in university and public research institutions as well as professional research and commercial-industrial applications in the area of product development, manufacturing and quality control.
It is also available as aqueous metal-free, stainless steel and multisolvent version and can be run with a broad range of aqueous and organic solvents. Planar Asymmetric Flow FFF (AF4) and circular HollowFiber Flow FFF (HF5) channels can used at the same time.
Various detection principles, such as UV-Absorbance (UV), Refractive Index (RI), Multi-Angle Light Scattering (MALS), Dynamic Light Scattering (DLS) and Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) can be coupled easily.
Temperature control is not only available for the separation channel but also for the entire system, including the transfer capillaries between the various modules and detectors.
AF2000 HT - Toplevel High Temp Flow FFF
The AF2000 HT is a special temperature controlled top-level Flow FFF system, which is ideal for the use in research, development and quality control of polyolefins and high temperature macromolecules in universities, public research institutions and industry.
It is available as stainless steel version and can be run with organic solvents from ambient temperature up to high temperature conditions.
Special planar Asymmetric Flow FFF (AF4) channels made from stainless steel and ceramics are exclusively employed for this conditions. As detection principles Infrared (IR), Refractive Index (RI), Multi-Angle Light Scattering (MALS) and Viscometry (Visco) can be used.
Advanced Flow FFF Detection
In order to enable the user to fully access this wide application range, the AF2000 MultiFlow is available in different unique versions.
Various add-on modules, extra options and special FFF detectors are available, such as Refractive Index (RI), Multi-Angle Light Scattering (MALS) and Dynamic Light Scattering (DLS).
All Postnova FFF modules and detectors have been especially developed for FFF and are perfectly optimized not only for the use with the AF2000 MultiFlow FFF, but also for the other Postnova FFF versions.
Additionally the AF2000 Series has been designed for easy interfacing with existing high-end detection technologies from leading instrument suppliers, so that the user can ideally integrate the Postnova FFF technology into the existing laboratory infrastructure in order to maximize efficiency and investment.
Features
- Unique Channel Cartridge Design
- Complete Bio-Compatible System
- Totally Integrated One-Box-System
- Syringe Pump Cross-Flow Control
- Data Evaluation Software - NovaFFF Analysis
- Integrated Method Wizard Expert System
- Unique FOCUS Technology
- Flexibility & Interfaceability
Applications
- Biotechnology: Viruses, Aggregates, Cell Organelles, Bioparticles
- Pharma: Proteins, Antibodies, Liposomes, Drug Delivery, Micelles
- Environment: Humic and Fulvic Acid, Environmental Colloids, Clay Particles
- Material Science: Latex Beads, Nanoparticle, High-Tech Nano Materials
- Polymers: Biopolymers, Starches, Polyelectrolytes, Technical Polymer