Parkinson's Disease

This hub offers a comprehensive exploration of Parkinson’s disease, integrating the latest scientific understanding, clinical practice, and emerging research. The linked articles cover the fundamentals of Parkinson’s disease pathophysiology, diagnosis, treatment strategies, and prognosis, while also examining associated conditions, genetic factors, and disease-modifying therapies. Readers will find evidence-based guidance on symptom management, including motor and non-motor features, along with in-depth discussions on neuroprotective interventions, the gut-brain axis, and the role of comorbidities. The collection also addresses the psychosocial impact of Parkinson’s disease, support resources, and advances in experimental therapies. Whether you are a healthcare professional, researcher, patient, or caregiver, these resources provide authoritative insights into the complex landscape of Parkinson’s disease.

Does Exercise Slow Parkinson's Disease Progression?

A growing pool of evidence suggests that high-intensity physical exercise may have beneficial outcomes in PD patients.

Developing Drugs for Neurodegenerative Diseases

Parkinson's Disease and Helicobacter Pylori

Parkinsonism in Spinocerebellar Ataxia

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Mythbusting: Misconceptions surrounding Parkinson’s Disease

Where Does Parkinson’s Disease Originate?

Herpes Virus and Parkinson's Disease

Parkinson’s Disease and Sleeping Disorders

Parkinson's Disease History

Parkinson's Disease and the Gut Microbiome

Progressive Supranuclear Palsy (PSP) Versus Parkinson's Disease

See more featured articles »

Gut-Brain Axis and Neurodegenerative Disorders

Bipolar Disorder and Parkinson’s

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Human brain may stay active for hours after death

Parkinson's Disease Research

Physiotherapy for Parkinson's Disease

Gut Bacteria Affecting Parkinson’s Treatment

Estrogen as a Treatment for Parkinson’s Disease

Parkinson's Disease Treatment

Gene Therapies for Parkinson’s Disease

Uncovering Hidden Symptoms: Hallucinations and Delusions in Parkinson’s Disease

Neurophysiotherapy for Parkinson's Disease

Parkinson's Disease Diagnosis

Identifying Early Symptoms in Parkinson’s

Thalamotomy, Pallidotomy and Subthalamotomy

Is Appendectomy Linked to Parkinson’s Disease?

VPS35 Gene and Parkinson's Disease

Parkinson's Disease Prognosis

Parkinson's Disease Support

Parkinson's Disease Pathophysiology

What is Parkinson's Disease?

Impact of COVID-19 on Parkinson's Disease

Latest Parkinson's Disease News and Research

New research highlights exercise's broad impact in Parkinson's disease

It was the early 2000s when researchers first showed that exercise can help relieve the tremors that are common with Parkinson's Disease.

4 Aug 2025

Subtle warning signs of MS can appear 15 years before diagnosis

The earliest warning signs of multiple sclerosis (MS) may emerge more than a decade before the first classical neurological symptoms occur, according to new research from the University of British Columbia.

1 Aug 2025

$5.5 million federal grant funds research to improve measurement of FXTAS treatments

UC Davis Health Professor of Psychiatry and Behavioral Sciences David Hessl will help lead a major research project to develop better ways to measure treatments for fragile X-associated tremor/ataxia syndrome (FXTAS).

31 Jul 2025

Machine learning detects early rising behavioral changes in mouse models of Parkinson’s disease

Detecting early rising Parkinson's disease (PD) symptoms could improve treatment outcomes by enabling earlier treatment interventions.

28 Jul 2025

Researchers discover new trigger for mitophagy

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists at the Max Perutz Labs at the University of Vienna investigated mitophagy - a form of autophagy - and came to a remarkable conclusion: the researchers have described a new trigger for mitophagy.

26 Jul 2025

AI-powered, speech-based screening tool offers new hope for early Parkinson’s detection

Computer scientists at the University of Rochester have developed an AI-powered, speech-based screening tool that can help people assess whether they are showing signs of Parkinson's disease, the fastest growing neurological disability in the world.

24 Jul 2025

Sound stress alone induces pain sensitivity and brain inflammation

Pain is an important physiological response in living organisms. While physical pain is an outcome of tissue damage, pain can manifest as diverse unpleasant sensory and emotional experiences. Many studies report that emotional or psychological stress enhances pain responses.

18 Jul 2025

Understanding brain activity during sleep to detect early neurological changes

"Complex processes are going on in the brain when we sleep," says Dr Karolina Armonaitė, a neuroscientist from Kaunas University of Technology, Lithuania. According to her, a more precise understanding of what happens in different areas of the cerebral cortex during sleep can help diagnose sleep disorders and neurological diseases more accurately.

18 Jul 2025

Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

17 Jul 2025

Standardized brain cell atlas to accelerate Parkinson's and Alzheimer's research

Researchers now have a powerful new way to understand the types of brain cells that are affected in neurodegenerative diseases and to uncover connections between conditions such as Parkinson's, Alzheimer's, and other forms of dementia.

17 Jul 2025

Trained dogs accurately detect Parkinson's disease from skin swabs

People with Parkinson's disease (PD) have an odor that can be reliably detected from skin swabs by trained dogs, a new study has shown.

15 Jul 2025

Study reveals dopamine sends precise signals rather than broad brainwide messages

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed.

12 Jul 2025

New device offers breakthrough for safe drug delivery into the brain

A new device combining ultrasound and advanced imaging to provide crucial information for the safe delivery of drugs into the brain has been developed by University of Queensland researchers.

11 Jul 2025

Weekly injectable drug offers hope for Parkinson's patients

A new weekly injectable drug could transform the lives of more than eight million people living with Parkinson's disease, potentially replacing the need for multiple daily tablets.

11 Jul 2025

New insights into neural replay and memory formation from flying bats

Every day, our brain takes countless fleeting experiences - from walks on the beach to presentations at work - and transforms them into long-term memories.

10 Jul 2025

Side of onset influences non-motor symptoms in Parkinson’s disease

Parkinson's disease often begins asymmetrically, affecting either the right or left side of the body first. Researchers from the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have demonstrated that this initial side of onset influences the progression of non-motor symptoms.

7 Jul 2025

Theater activities enhance emotional well-being in Parkinson’s patients

A research team at the Universitat Oberta de Catalunya (UOC), working with the Hospital Sant Pau in Barcelona, has shown that theatre can improve the emotional well-being of people with Parkinson's disease.

2 Jul 2025

Targeting a key enzyme could reverse early Parkinson's effects

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.

2 Jul 2025

Brain cells can burn fat to fuel activity

While glucose, or sugar, is a well-known fuel for the brain, Weill Cornell Medicine researchers have demonstrated that electrical activity in synapses—the junctions between neurons where communication occurs—can lead to the use of lipid or fat droplets as an energy source.

1 Jul 2025