Parkinson's Disease

This hub offers a comprehensive exploration of Parkinson’s disease, integrating the latest scientific understanding, clinical practice, and emerging research. The linked articles cover the fundamentals of Parkinson’s disease pathophysiology, diagnosis, treatment strategies, and prognosis, while also examining associated conditions, genetic factors, and disease-modifying therapies. Readers will find evidence-based guidance on symptom management, including motor and non-motor features, along with in-depth discussions on neuroprotective interventions, the gut-brain axis, and the role of comorbidities. The collection also addresses the psychosocial impact of Parkinson’s disease, support resources, and advances in experimental therapies. Whether you are a healthcare professional, researcher, patient, or caregiver, these resources provide authoritative insights into the complex landscape of Parkinson’s disease.

Does Exercise Slow Parkinson's Disease Progression?

A growing pool of evidence suggests that high-intensity physical exercise may have beneficial outcomes in PD patients.

Gut-Brain Axis and Neurodegenerative Disorders

Identifying Early Symptoms in Parkinson’s

Parkinson’s Disease and Sleeping Disorders

Gut Bacteria Affecting Parkinson’s Treatment

Herpes Virus and Parkinson's Disease

Parkinson's Disease and Helicobacter Pylori

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Human brain may stay active for hours after death

Parkinson's Disease Treatment

Is Appendectomy Linked to Parkinson’s Disease?

Parkinson's Disease Diagnosis

See more featured articles »

Estrogen as a Treatment for Parkinson’s Disease

Uncovering Hidden Symptoms: Hallucinations and Delusions in Parkinson’s Disease

VPS35 Gene and Parkinson's Disease

Gene Therapies for Parkinson’s Disease

What is Parkinson's Disease?

Bipolar Disorder and Parkinson’s

Impact of COVID-19 on Parkinson's Disease

Parkinson's Disease Research

Neurophysiotherapy for Parkinson's Disease

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Progressive Supranuclear Palsy (PSP) Versus Parkinson's Disease

Mythbusting: Misconceptions surrounding Parkinson’s Disease

Parkinson's Disease Pathophysiology

Parkinson's Disease Prognosis

Physiotherapy for Parkinson's Disease

Parkinson's Disease History

Parkinson's Disease Support

Parkinson's Disease and the Gut Microbiome

Parkinsonism in Spinocerebellar Ataxia

Developing Drugs for Neurodegenerative Diseases

Thalamotomy, Pallidotomy and Subthalamotomy

Where Does Parkinson’s Disease Originate?

Latest Parkinson's Disease News and Research

Mount Sinai researchers discover how Alzheimer's gene damages blood vessels

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

24 Sep 2026

PsychAD studies map molecular mechanisms across major brain disorders

Research led by Mount Sinai scientists within the PsychAD Consortium, a large-scale, multidisciplinary initiative launched in 2019 with support from the National Institute on Aging (NIA), is featured in a landmark collection of nine papers published across the Nature family of journals that maps the molecular mechanisms underlying Alzheimer's disease, Parkinson's disease, schizophrenia, and other brain disorders.

23 Sep 2026

Experimental drug reverses multiple sclerosis damage in mouse model

A drug developed by a UVA Health scientist has not only stopped but reversed paralysis and vision loss in a mouse model of multiple sclerosis.

23 Sep 2026

Genetic system converts scar-forming cells into neurons to restore movement after spinal cord injury

What if cells that form scars after a spinal cord injury could become part of the repair process? Researchers have developed a genetic system that converts certain scar-forming cells into neurons, improving movement in mice and rats with spinal cord injuries.

23 Sep 2026

Flatworm genes reveal secrets to regrowing damaged brain cells

The human brain is terrible at healing itself from injury or disease. But some animals can harness their own cellular abilities to not only repair injuries but also to regrow their brains entirely.

21 Sep 2026

Time-restricted eating may slow early-stage Huntington's disease

A simple change in when people eat may offer a promising new approach for Huntington's disease, according to research led by Oregon Health & Science University.

17 Sep 2026

Norwegian scientists harvest super donor cells to fight diverse diseases

Cells from nine "super donors" are being collected in Oslo. The aim is for these to be used to repair or replace damaged cells, tissue and organs in people suffering from conditions ranging from heart attacks to Parkinson's disease.

16 Sep 2026

Eye scans detect signs of atrial fibrillation years before diagnosis

People with atrial fibrillation have signs of the condition in the retinas of their eyes that can be detected as early as four years before diagnosis, finds a new study led by University College London (UCL) and Moorfields researchers.

14 Sep 2026

Review highlights solute carriers as targets for central nervous system disorders

Solute carriers (SLCs) are specialized transport proteins that control the movement of nutrients, ions and neurotransmitters across cell membranes and are essential for brain metabolism and neuronal communication.

10 Sep 2026

Brain-protecting immune cells may actually drive Alzheimer's disease

Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer's disease and related disorders at much higher levels than in healthy brains.

3 Sep 2026

Coffee’s link to Parkinson’s risk may depend on how your body handles caffeine

In 435,551 UK Biobank participants followed for a median of 15.7 years, overall coffee consumption was not associated with Parkinson’s disease risk, but the relationship differed significantly according to CYP1A2 genotype. Lower risk was observed with low-to-moderate coffee intake among fast-metabolizer AA carriers, while higher intake was associated with increased risk among AC and CC carriers, although the observational findings do not establish causality and sex-specific patterns require cautious interpretation.

2 Sep 2026

Study uncovers cause of abnormal breathing in Rett syndrome

Hyperventilating. Breath holding until they turn blue. This abnormal breathing is frequent and disturbing in people with Rett syndrome, a rare genetic disease.

1 Sep 2026

AI platform uncovers new molecular targets for Alzheimer's disease

Groundbreaking study published in Alzheimer's & Dementia reveals the crucial links between the NAD⁺-mitophagy axis and neurodegeneration.

1 Sep 2026

GLP-1 drugs have benefits beyond weight loss. Could microdoses preserve them?

A narrative review suggests GLP-1-based therapies deliver metabolic, cardiovascular, renal, and other systemic benefits, raising interest in whether lower fractional doses could improve tolerability and treatment continuity. However, direct evidence for GLP-1 microdosing remains extremely limited, and researchers say prospective studies are needed to determine whether lower doses preserve long-term benefits.

1 Sep 2026

Parkinson’s disease imposes €22.8 billion economic burden across Europe

The annual societal cost of Parkinson's disease across Europe reached €22.8 billion in 2019, equivalent to €28.8 billion at 2025 prices, a new study published today in Movement Disorders has shown.

27 Aug 2026

Egg yolk peptides protect brain cells from oxidative stress

As the human lifespan increases, so too does the risk of developing neurological disorders such as Parkinson's disease, Alzheimer's disease, anxiety and depression.

27 Aug 2026

Tea, berries and dark chocolate featured in a diet linked to lower Parkinson’s risk

A prospective UK Biobank study of 123,655 adults found that a dietary pattern richer in flavonoid-containing foods was modestly associated with a lower incidence of hospital-recorded Parkinson’s disease. The association was strongest among those with the highest flavonoid diet scores, while exploratory proteomic and transcriptomic analyses pointed to possible neuroimmune and cell-adhesion pathways but did not establish causality or mechanism.

26 Aug 2026

Gut bacteria may send different biological signals in Parkinson’s disease

A new study from the University of Oulu suggests that gut bacteria may send different biological signals in Parkinson’s disease.

26 Aug 2026

FDA endorses alpha-synuclein biomarker for Parkinson’s clinical trials

Critical Path Institute® (C-Path) today announced the publication of "Regulatory endorsement for the application of alpha-synuclein seed amplification assay (αSyn-SAA) as a susceptibility and risk biomarker for clinical trials targeting synucleinopathies" in the Journal of Parkinson's Disease, marking a significant milestone for its Critical Path for Parkinson's consortium.

25 Aug 2026

Emergency diagnoses of medical conditions predict worse patient survival

Patients diagnosed with conditions after an emergency hospital admission or an emergency room visit face a higher risk of death than those diagnosed in non-emergency settings, according to a large population-based study by Emma Whitfield and colleagues from University College London, UK, published August 25th in the open access journal PLOS Medicine.

25 Aug 2026