The hematological testing requirements of today’s high-volume labs are met by the Atellica® HEMA 570 and 580 Analyzers. The instruments have an equal footprint and quick throughput. They are designed to partner with advanced informatics and automation solutions to meet workflow demands and boost efficiency across labs and networks.
They provide a variety of analytical capabilities, including an eight-part white blood cell differential, with the Atellica HEMA 580 Analyzer giving a more comprehensive selection that includes optical platelet and reticulocyte testing.
Features and benefits
Automation, intelligence, and extended parameters—seamlessly integrated to streamline testing
The Atellica HEMA 570 and 580 Analyzers are high-volume, fully automated hematology analyzers. They offer:
Adaptive scalable solutions
Image Credit: Siemens Healthineers
Multidisciplinary integration and dedicated hematology are likely to benefit from flexible automation connectivity.
Data-driven performance
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Atellica Diagnostics IT’s full integration strives to standardize and improve inventory, process, and result management at the lab or network level.
Extended parameters
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Up to 55 CBC, differential, and reticulocyte parameters can be measured using flow cytometry, which integrates optical methodologies.
Take a tour of the analyzers’ features
Two high-volume hematology analyzer models to match your clinical needs
Image Credit: Siemens Healthineers
- Atellica HEMA 570 Analyzer
- Parameters: 43; 8-part differential
- Optical platelet method (PLTO): No
- Reticulocytes: No
- Body fluids (cerebrospinal, pleural, peritoneal, synovial): Yes
- Extended counting for low values (LVC): Yes
- Optional automated slide making and staining: Yes
- Atellica HEMA 580 Analyzer
- Parameters: 55; 8-part differential
- Optical platelet method: Yes
- Reticulocytes: Yes
- Body fluids (cerebrospinal, pleural, peritoneal, synovial): Yes
- Extended counting for low values (LVC): Yes
- Optional automated slide making and staining: Yes
Sensibly designed to easily meet demanding turnaround times
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- Offers fast throughput of up to 120 tests/hour (CBC/DIFF)
- Automated rack processing makes walkaway operations (120-tube initial load) possible, and additional STAT/specialty tube loading options are also available.
- Daily maintenance is automated for minimal hands-on time
- Onboard reagents use a simple load-and-go system for quick replacement
The Atellica HEMA Analyzers use data to drive performance with support from our wide range of digital solutions, including the open and scalable Atellica Diagnostics IT.
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- Atellica Data Manager’s customizable auto-verification rules and built-in quality control functionality make standard testing procedures and result management possible.
- Atellica Process Manager assists laboratories with integrated analytics in standardizing and improving procedures.
- The control of reagents and consumables across several sites is automated using Atellica Inventory Manager
- Smart Remote Services (SRS) can offer quick error detection, remote software upgrades, and maintenance
Most testing processes across the lab or network can be consolidated with a single IT platform by integrating hematology into a multidisciplinary digital ecosystem.
Extended parameters and enhanced technologies for accurate detection of abnormalities
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- A wide range of parameters are available, including reflexive platelet measurements (PLTo) and innovative immature white blood cell analysis (granulocytes, monocytes, and lymphocytes)
- For a more homogenous sample that supports reliable first-pass results, 360-degree mixing spins tubes 40 times
- Optical extinction technology is used in the double hydrodynamic sequential system (flow cytometry) to assist in minimizing the risk of interference and repeat testing
- Powered by Atellica Data Manager, integrated rules-based intelligence standardizes result interpretations with customized flagging and auto verification
Siemens Healthineers, a leader in whole lab automation, intends to provide connectivity to Aptio® Automation, allowing for interdisciplinary integration and completely one-touch workflow with various pre- and post-analytical modules.
Automated slide making and staining capabilities support diverse needs
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- 120 slides/hour throughput with a 160-slide initial-load capacity and continuous loading
- User-defined/adjustable smearing profiles that use 75 µL of sample
- Three slide staining protocols: Wright-Giemsa, Modified Wright-Giemsa, May-Grünwald Giemsa
- 2D barcode (CellaVision®-compatible) or three-line printing for identification
Flexible workcell integration aims to minimize labor and footprint
Siemens Healthineers intends to provide the Atellica HEMA Workcell to laboratories looking to improve throughput and decrease hands-on time in a dedicated hematology solution. The objective is to boost testing capacity by integrating numerous Atellica HEMA 570 and 580 Analyzers into a system that can be configured to fit the layout of the laboratory.
Design objectives:
- To reach a throughput of up to 720 tests per hour, combine up to six analyzers
- To meet space limitations, it provides linear, L, U, and island-shaped (back-to-back) configurations
- Easily distribute workloads across analyzers using the bidirectional conveyor and intelligent software features of the Atellica HEMA Transport
- Perform all necessary hematology tests, reruns, and reflexes without handling sample racks by hand
Technical specifications
Table 1. Dimensions. Source: Siemens Healthineers
| . |
. |
| Atellica HEMA 570 and 580 Analyzers |
73 cm (h) x 87 cm (w) x 67 cm (d) |
| Optional slidemaker stainer |
44 cm (h) x 91 cm (w) x 72 cm (d) |
Table 2. Sample capacity. Source: Siemens Healthineers
| Tes |
test |
| Automatic rack loading (Closed tube) |
120-tube capacity (12 racks with 10-tube capacity) |
| STAT loading (Closed/open tube) |
1-tube capacity |
Table 3. Sample modes/volume. Source: Siemens Healthineers
| . |
. |
| Automatic rack mode (Closed tube) |
110 µL |
| STAT mode (Closed/open tube) |
110 µL |
Table 4. Throughput/test selectivity. Source: Siemens Healthineers
| . |
. |
| CBC |
120 samples/hour |
| DIFF (including NRBC) |
120 samples/hour |
| RET* |
60 samples/hour |
| DIR (including NRBC)* |
60 samples/hour |
| CBR* |
60 samples/hour |
| DIFF_LV |
60 samples/hour |
| RBC_PLTO* |
60 samples/hour |
| *Atellica HEMA 580 Analyzer only. |
|
Table 5. Data management. Source: Siemens Healthineers
| . |
. |
| Database |
100,000-patient storage capacity, including graphics |
| Review and edit capability |
Atellica Data Manager enables user-defined windows, reports, and ranges based on age and sex for normal range, panic, rerun, and delta check criteria |
| Extensive quality control (QC) management |
Z-score, Levey-Jennings graphs, Westgard rules, patient moving average (enabled by Atellica Data Manager), QC file management |
Table 6. Parameters. Source: Siemens Healthineers
| . |
. |
| CBC results |
WBC, RBC, HGB, HCT, MCV, MCH, MCHC, RDW-CV, RDW-SD, MIC%,* MAC%,* PLT, MPV, PCT,* PDW,* NRBC (absolute and %) |
Differential results
(Absolute and %) |
LYM, MON, NEU, EOS, BAS, ALY,* LIC,* IMG,* IML,* IMM* |
Platelet results
(Optical)† |
PLTO |
| Reticulocyte results† |
RET (absolute and %), RETL%,* RETM%,* RETH%,* CRC%, MRV,* MFI,* IRF, RHCc, PIC* |
Body fluid results
(Cerebrospinal, pleural, peritoneal, and synovial fluids) |
BFWBC, BFRBC, absolute and % BFMN, BFPN |
*For research use only (RUO).
†Atellica HEMA 580 Analyzer only. |
|
Table 7. Linear ranges. Source: Siemens Healthineers
| . |
. |
| WBC |
0.1–300 x 103/mm3 |
| RBC |
0.3–8 x 106/mm3 |
| PLT |
(HGB >2) 10–2500 x 103/mm3
(HGB <2) 10–5000 x 103/mm3 |
| HGB |
0.8–24 g/dL |
| RET%* |
0.3–35 (%) |
| *Atellica HEMA 580 Analyzer only. |
|
Table 8. Precision. Source: Siemens Healthineers
| Parameter |
Low Level |
Normal Level |
High Level |
CV
Limits (%) |
Range |
CV
Limits (%) |
Range |
CV
Limits (%) |
Range |
| WBC |
5 |
0.3–4 x 103/mm3 |
2 |
4–10 x 103/mm3 |
2 |
10–300 x 103/mm3 |
| RBC |
2.5 |
0.5–3.6 x 106/mm3 |
2 |
3.6–6.2 x 106/mm3 |
1.5 |
6.2–8 x 106/mm3 |
| HGB |
1.5 |
2–12 g/dL |
1 |
12–18 g/dL |
1 |
18–24 g/dL |
| MCV |
1 |
Min. to 80 fL |
1 |
80–100 fL |
1 |
100 to max. fL |
| PLT |
10 |
30–150 x 103/mm3 |
5 |
150–500 x 103/mm3 |
3 |
500–1000 x 103/mm3 |
| RET%* |
– |
– |
12 |
0.5–3 (%) |
8 |
3 to max. (%) |
*Atellica HEMA 580 Analyzer only.
Combining 80 years of leadership in hematology, IT, and automation
The Atellica HEMA Analyzers have been developed to smoothly interface with various digital and workflow solutions that assist in streamlining clinical operations, whether the hematology testing is completely integrated or stand-alone.
Atellica Data Manager
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Enables uniform testing procedures and result management across networks and in labs.
Atellica Process Manager
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Provides built-in analytics and business intelligence solutions that help laboratories standardize and improve procedures.
Atellica Inventory Manager
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Reduces costs, saves time, and enhances lab quality by automating control of reagents and consumables across numerous sites.
Aptio Automation
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Enables laboratories to achieve consistent TAT, optimize resource use, boost efficiency, and speed up processing.