The next-generation fluorescent imaging technology, CloneSelect® Imager FL, ensures automated confluence and monoclonality across various cell types.
The CloneSelect® Imager FL is a cutting-edge solution for quick and precise monoclonality verification and gene edit identification. It employs high-contrast fluorescent and white light imaging to detect single cells accurately from the onset.
The system’s high-throughput capability streamlines workflows, allowing researchers to efficiently confirm monoclonality and gene edits with comparative confluence assays. This innovative system enhances both speed and accuracy in cell line development.
Benefits
Demonstrated IND success
The Monoclonality Report feature simplifies the process of creating supporting documentation for regulatory agencies. Users can select parameters to generate reports automatically. The Monoclonality Report is an audit-ready document that can be used to support filing for an Investigational New Drug (IND) Application with the FDA. This filing falls under the regulatory guidelines specified in 21 CFR Part 312.
Multichannel imaging and automated confluence
Highly efficient algorithms are utilized to ensure precise detection of cells, catering to different types of cells and environmental conditions. The imaging generated is of superior quality, enabling automatic analysis of cell confluency and ensuring monoclonality, making it suitable for publication purposes.
Rapid single-cell confirmation
The acquisition times of the imager are unparalleled, capable of imaging a 96-well plate in just two minutes. The imager has fluorescence technology, enabling monoclonality verification from day zero.
White light and fluorescent imaging
This technology allows for quick and thorough imaging using both white light and multichannel fluorescence, which enhances the level of confidence in monoclonality and facilitates the assessment of cell confluence.
Data tools to accelerate research timelines
The process of cell line development from imaging to IND filing is streamlined through the integration of automatic confluence calculations and growth curve generation.
Quickly image a variety of plate formats and cell types
It is capable of imaging a 96-well plate within two minutes with high efficiency. Additionally, it is compatible with a wide range of cell types, including CHO and HEK.
Intelligent analysis with easy-to-use software
It offers an automatic calculation of confluence for every period, which results in a thorough growth analysis with an easy-to-use interface that requires minimal training.
High-resolution images
This system integrates rapid fluorescence with precise white light imaging to facilitate the thorough detection of individual cells and enable extended data monitoring.
Custom automation options
Tailored automation solutions are available, ranging from basic robotic plate loading to advanced workstations that can accommodate diverse research needs, including iPSC studies and drug toxicity research.