Proline Promass U 500: Single-use flowmeter for biotech applications

The Proline Promass U 500 Coriolis flowmeter is the first single-use flowmeter for biotech applications, offering superior performance, cGMP compliance, and up to four I/Os.

Overview

Specs at a glance

Max. measurement error

Liquid mass flow: ±0.5%

Measuring range

0 to 75 kg/h (0 to 165.3 lb/min)

Medium temperature range

37.4 to 140 °F (3 to 60 °C)

Max. process pressure

6 bar, or 87 psi

Wetted materials

316 L and 1.4435 stainless steel measuring tubes; Makrolon Rx 1805 polycarbonate for the hole connection nipple

Premium performance and cGMP compliance with single-use flowmeter Proline Promass U 500. Image Credit: Endress + Hauser

Field of application

The Promass U 500 is the best single-use flowmeter for biopharmaceutical applications in the life sciences sector. It reacts to the transition from batch to continuous manufacturing and multi-use to single-use gadgets.

Promass U 500, which offers multivariable measurement, offers improved accuracy, industry compliance, and dependability in accordance with cGMP. The flowmeter is well-suited for upstream and downstream uses in producing monoclonal antibodies (mAb).

The sensor consists of a permanently installed base unit that fits all line diameters and a disposable portion that comes in four line sizes. Following installation, Heartbeat Technology automatically detects the flow range and confirms the accuracy of the factory calibration.

This removes the requirement for field calibration and streamlines commissioning. The transmitter offers simple operation, extra processes, and device information thanks to its integrated web server, WLAN, and up to four I/Os.

Benefits

• Best-in-class measuring accuracy: Coriolis technology with multivariable measurement
• Highest turndown ratio: Single sensor that works with all disposable line sizes
• cGMP compliance: Created in accordance with the most recent standards and directives, furnished with the necessary characteristics and records
• Simple, fast commissioning: Automated calibration data transfer and one-hand mounting
• Self-drainability or air bubble escape: Thanks to the variable mounting angles
• No field calibration needed: Automated verification with integrated Heartbeat Technology
• Digital integration: Modern communication systems based on single-pair Ethernet

Specifications

• Measuring / Application task
  • Liquids

• Measuring principle: Coriolis
• Product headline
  • Single-use customized for biotech applications, including a remote version enabling up to four I/Os.
  • Modern fieldbus communication protocols (2-wire)
  • The highest measurement performance for liquids in single-use processes in the Life Sciences Industry

• Sensor features
  • One sensor fits all DN - a single type with four disposable line sizes delivers the maximum turndown ratio. One-handed mounting of a throwaway - simple
  • Mounting angle - self drainabillity or air bubble escape
  • Disposable manufactured from 1.4435 (316L) and polycarbonate. Completely traceable cGMP compliance. One sensor accommodates four line sizes from ¹⁄₈ to 1”
• Transmitter features
  • Complete access to diagnostic and process data via Ethernet and a variety of flexibly combinable I/Os. I/O functionality that is freely customizable results in less complexity and variation. Heartbeat Technology is used for integrated verification
  • Remote version supports up to four I/Os. Backlit display with touch controls and WLAN access. Standard cable connects sensor and transmitter
• Nominal diameter range
  • ¹⁄₈" to 1”
• Wetted materials
  • Measuring tubes: Stainless steel 1.4435, 316L
  • Hose connection nipple: Makrolon Rx 1805 polycarbonate
• Measured variables
  • Mass, density, temperature
• Max. measurement error
  • Mass flow (liquid): ±0.5%
• Measuring range
  • 0 to 75 kg/h (0 to 165,3 lb/min)
• Max. process pressure
  • 6 bar (87 psi)
• Medium temperature range
  • 3 to 60 °C (37.4 to 140 °F)
• Ambient temperature range
  • 5 to 40 °C (41 to 104 °F)
• Transmitter housing material
  • Aluminum, AlSi10 Mg, coated
• Degree of protection
  • Transmitter: IP66/67, Type 4X enclosure
  • Sensor: IP54
• Display/Operation
  • Configuration through local display and operating tools is possible
  • 4-line backlit display with touch control (operated from outside)
• Outputs
  • 4 outputs:
  • 4-20 mA HART (active/passive)
  • 4-20 mA WirelessHART
  • 4-20 mA (active/passive)
  • Pulse/frequency/switch output (active/passive)
  • Double pulse output (active/passive)
  • Relay output
• Inputs
  • Status input
  • 4-20 mA input
• Digital communication
  • Modbus RS485, PROFINET over Ethernet-APL
• Power supply
  • AC 100 to 230 V / DC 24 V (non-hazardous area)
• Product safety
  • CE, C-tick, EAC marking
• Functional safety
  • Functional safety according to IEC 61508 and is applicable in safety-related applications in line with IEC 61511
• Hygienic approvals and certificates
  • cGMP compliance, ASME BPE, BPOG, FDA

Smart instrumentation through Heartbeat Technology

Want to boost plant performance while minimizing costs? The smart instrumentation range, with Heartbeat Technology, provides detailed device insight for increased cost-efficiency and operational safety.

Xpert selection

Image Credit: Endress+Hauser

• Made for challenging applications
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