Disease/Infection News

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Dying cells trigger a lethal cascade in sepsis

Like a poison pen, dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues in the UConn School of Medicine report in the Jan. 23 issue of Cell. Their findings could lead to a new understanding of this dangerous illness.

25 Jan 2025

Innovative approach tracks SARS-CoV-2 in the blood to guide COVID-19 treatment

Investigators from Mass General Brigham have found that a method originally designed for cancer detection can also identify and monitor even tiny amounts of SARS-CoV-2 intact viral particles in blood and other fluids from patients with acute COVID-19 infections, creating the potential for guiding future treatment of patients. The research is published in Science Advances.

25 Jan 2025

Dapagliflozin plus calorie restriction boosts remission rates in adults with type 2 diabetes and obesity

Findings indicate that dapagliflozin and calorie restriction together improve weight loss and metabolic health, increasing the likelihood of diabetes remission.

24 Jan 2025

WHO certifies Georgia as malaria-free

Following a nearly century-long effort, Georgia has been certified malaria-free by the World Health Organization (WHO). With today's announcement, Georgia joins the ranks of 45 countries and 1 territory that have achieved this milestone.

24 Jan 2025

New compound V-161 offers hope in the fight against antibiotic-resistant bacteria

V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly reduces bacterial growth and colonization.

23 Jan 2025

USF study: Pulmonary fibrosis after COVID-19 tends to get better

Pulmonary fibrosis is a rare, chronic disease that causes scarring in the lungs, making breathing difficult for people who suffer with it.

23 Jan 2025

EU-funded Vigilant network aims to develop broad-spectrum antiviral drugs

Pandemics threaten both human health and the global economy. Vaccines are an essential part of the fight against pandemics, but they are only available months after the outbreak

23 Jan 2025

Empa researchers improve epidemic forecasts with reproduction matrix

The reproduction number R is often used as an indicator to predict how quickly an infectious disease will spread.

23 Jan 2025

Penn researchers develop optimized framework for COVID-19 vaccination distribution

Engineering and medical researchers at Penn have developed a groundbreaking framework that can determine the best and most computationally optimized distribution strategy for COVID-19 vaccinations in any given community.

22 Jan 2025

New technique identifies SARS-CoV-2 in blood and other fluids with high sensitivity

22 Jan 2025

U.S. mosquito species show minimal risk of spreading Oropouche virus, study finds

US mosquito species exhibit minimal competence for transmitting Oropouche virus (OROV), with low infection and transmission rates across tested populations, suggesting limited potential for local outbreaks despite rising imported cases.

22 Jan 2025

Social interventions could lead to major drop in national HIV incidence

Researchers at the University of Massachusetts Amherst have quantified the impacts of a constellation of social factors on the spread of HIV.

22 Jan 2025

Antidepressant fluoxetine found ineffective for early COVID-19 treatment

Findings reveal fluoxetine's weak antiviral effects in COVID-19, with no significant benefits in symptom resolution compared to other antiviral treatments.

22 Jan 2025

Study sheds light on the dynamics of non-persistent HPV infections

Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a study published January 21st in the open-access journal PLOS Biology by Samuel Alizon of the National Centre for Scientific Research (CNRS), France, and colleagues.

21 Jan 2025

Tanzania's announces Marburg virus outbreak with single case in Kagera

Tanzania's President Samia Suluhu Hassan has declared an outbreak of Marburg virus, confirming a single case in the northwestern region of Kagera after a meeting with WHO director-general Tedros Adhanom Ghebreyesus.

21 Jan 2025

Short-course antibiotics can be a game-changer in tackling ventilator-associated pneumonia

Antibiotic overuse is a key driver in the rise of antimicrobial resistance (AMR), a major global health crisis.

21 Jan 2025

New EU project aims to advance pandemic preparedness

With viral disease emergence expected to accelerate, preparing for possible future pandemics is paramount.

21 Jan 2025

Azvudine beats paxlovid in reducing COVID-19 deaths

In hospitalized COVID-19 patients, azvudine shows lower all-cause mortality and fewer adverse events than Paxlovid, with added antitumor effects observed.

21 Jan 2025

Rising Toscana virus infections in Italy highlight climate-driven health risks

A recent study reveals a sharp rise in neuroinvasive Toscana virus infections in Italy from 2022 to 2023, driven by climate factors and expanding geographic spread.

20 Jan 2025

Breakthrough study maps critical structure of Nipah virus polymerase

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.

20 Jan 2025