Drug Discovery & Pharmaceuticals

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Degron Therapeutics announced as winner of AFCR's 2023 BRACE Award Venture Competition

The Asian Fund for Cancer Research (AFCR) is pleased to announce that Degron Therapeutics was selected as the winner of the 2023 BRACE Award Venture Competition.

27 Dec 2023

Researchers receive two grants to study tuberculosis drug development

Weill Cornell Medicine researchers and the TB Drug Accelerator have received two grants totaling $6.8 million from the Bill & Melinda Gates Foundation to study tuberculosis (TB) drug development.

26 Dec 2023

First new antibiotic class in decades discovered using explainable AI platform

Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning.

20 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

Scientists crack the code for targeting cancer's 'death star' protein

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS.

18 Dec 2023

Deep learning designs high-affinity protein binders for bioactive helical peptides

A new study Dec. 18 in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring.

18 Dec 2023

New discovery could expand the possibilities for medical use of Botox

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent.

18 Dec 2023

Expanding the toolbox for drug design: New enzymes for tailoring molecules

Simon Schröder has worked out how enzymes can be used to more easily form the desired bond between two nitrogen atoms.

8 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

Design modifications offer promise for safer and more effective mRNA therapeutics

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body.

6 Dec 2023

MedUni Vienna scientists discover new pain medication with fewer side effects

People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects.

6 Dec 2023

Revolutionary self-folding nanoscale MRI agent sharpens cancer imaging

Study introduces a novel self-folding nanoscale contrast agent for MRI, enhancing tumor visualization with lower gadolinium loads and reduced risk of adverse effects.

5 Dec 2023

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms.

5 Dec 2023

Government’s £2 billion plan sets out to harness the power of engineering biology

The government's £2 billion vision to seize the enormous potential of engineering biology - an exciting field of biology which could transform how we sustainably grow food, create medical treatments and produce fuel - will be unveiled by Science, Research and Innovation Minister Andrew Griffith today (Tuesday 5 December).

5 Dec 2023

C-Path's TRxA and Celdara Medical announce MOU to identify and advance promising new therapeutics

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) and Celdara Medical today announced the signing of a Memorandum of Understanding (MOU) aimed at identifying and advancing promising new therapeutics in areas of high unmet medical need.

29 Nov 2023

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

Insilico Medicine ("Insilico"), an artificial intelligence (AI)-driven, clinical stage biotechnology company and leader in AI drug discovery platform technology, is hosting three webinars unveiling its latest technology breakthroughs Nov. 28-30, 2023.

29 Nov 2023

AI predicts ideal sites for chemical alterations in drug molecules

Researchers have developed an AI model that can predict where a drug molecule can be chemically altered.

29 Nov 2023

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Pioneering epigenome editing company Tune Therapeutics has announced it is working on a new and potentially curative approach to treating chronic HBV infection.

20 Nov 2023

Almirall and Absci partner to develop AI-designed therapeutics for dermatological diseases

Almirall S.A., a global biopharmaceutical company focused on medical dermatology, and Absci Corporation, a generative AI drug creation company, today announced a drug discovery partnership aimed to develop and commercialize AI-designed therapeutics to fight chronic and debilitating dermatological diseases. The partnership combines Absci’s Integrated Drug Creation™ platform with Almirall’s dermatological expertise with the goal of delivering life-changing medicines to patients, marking another step forward in AI drug creation.

20 Nov 2023

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer.

17 Nov 2023

Drug Discovery & Pharmaceuticals

Degron Therapeutics announced as winner of AFCR's 2023 BRACE Award Venture Competition

Researchers receive two grants to study tuberculosis drug development

First new antibiotic class in decades discovered using explainable AI platform

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Scientists crack the code for targeting cancer's 'death star' protein

Deep learning designs high-affinity protein binders for bioactive helical peptides

New discovery could expand the possibilities for medical use of Botox

Expanding the toolbox for drug design: New enzymes for tailoring molecules

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Design modifications offer promise for safer and more effective mRNA therapeutics

MedUni Vienna scientists discover new pain medication with fewer side effects

Revolutionary self-folding nanoscale MRI agent sharpens cancer imaging

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Government’s £2 billion plan sets out to harness the power of engineering biology

C-Path's TRxA and Celdara Medical announce MOU to identify and advance promising new therapeutics

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

AI predicts ideal sites for chemical alterations in drug molecules

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Almirall and Absci partner to develop AI-designed therapeutics for dermatological diseases

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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