Drug Discovery & Pharmaceuticals

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A novel strategy to achieve site-selective chiral drug synthesis in living systems

Enantioselectivity plays an important role in the pharmacological and toxicological processes of chiral drugs.

26 Jun 2020

Chemically engineered peptides could help fight persistent human health challenges

Chemically engineered peptides, designed and developed by a team of researchers at Rensselaer Polytechnic Institute, could prove valuable in the battle against some of the most persistent human health challenges.

26 Jun 2020

New steroid compounds from deep-water starfish show anticancer activity

Russian scientists from Far Eastern Federal University, G. B. Elyakov Pacific Institute of Bioorganic Chemistry, and A.V. Zhirmunsky National Scientific Center for Marine Biology have discovered four new steroid substances which target cells of human breast cancer, and colorectal carcinoma.

26 Jun 2020

GlobalData: Uncertainty during COVID-19 increases demand for immunity-boosting products

Ongoing research around protective immunity against COVID-19 has not yet helped to define ways of how the public can protect themselves from the illness, minimize the symptoms, and avoid re-infection.

26 Jun 2020

Academy of Finland funds projects for vaccine and drug development for COVID-19

The Academy of Finland has selected the projects to be funded from the call for research into COVID-19 vaccines and pharmaceutical development.

25 Jun 2020

Researchers investigate nelarabine drug for treating leukemia

Acute lymphoblastic leukemia (ALL) is the most common kind of cancer in children. T-ALL, a subtype that resembles T-lymphocytes, can be treated successfully with the drug nelarabine.

24 Jun 2020

New virtual incubator can catalyze early-stage drug discovery and development

Samsara BioCapital, a leading life sciences investment firm, Evotec SE, a global drug discovery alliance and development partnership company (Frankfurt Stock Exchange: EVT, MDAX/TecDAX, ISIN: DE0005664809), and KCK Ltd., a family investment fund, today announced the launch of Autobahn Labs, a novel virtual incubator partnering with top academic and research institutions to catalyze early-stage drug discovery and development.

24 Jun 2020

UK announces research partnership with Atomwise to explore potential COVID-19 therapies

The University of Kentucky announced a research collaboration with Atomwise, an industry leader in using artificial intelligence (AI) for small molecule discovery, to explore potential COVID-19 therapies

23 Jun 2020

Chemist develops new drug to treat type 2 diabetes without undesired side effects

Syracuse University chemistry professor Dr. Robert P. Doyle has developed a new drug lead to treat type 2 diabetes in millions of patients who are seeking to better control their blood sugar without the common side effects of nausea, vomiting, and in select cases, undesired weight loss.

23 Jun 2020

Jubilant Therapeutics announces preclinical data of dual LSD1 and HDAC6 inhibitor at AACR 2020

Jubilant Therapeutics Inc., a biopharmaceutical company advancing small molecule modulators to address unmet medical needs in oncology and autoimmune diseases, today announced that preclinical data of dual LSD1 and HDAC6 inhibitor JBI-802, will be presented in a poster session at the American Association for Cancer Research 2020 Virtual Annual Meeting II.

23 Jun 2020

UQ superbug drug discoveries will be fast-tracked under international research deal

Antibiotics discovered at The University of Queensland will be fast-tracked under an US$11 million international research deal.

22 Jun 2020

UAH researchers assess treatment efficacy of naturally occurring compounds against COVID-19

The Baudry Lab at The University of Alabama in Huntsville has identified 125 naturally occurring compounds that have a computational potential for efficacy against the COVID-19 virus from the first batch of 50,000 rapidly assessed by a supercomputer.

22 Jun 2020

Researchers produce first fully-glycosylated full-length SARS-CoV-2 spike protein models

The virus SARS coronavirus 2 (SARS-CoV-2) is the known cause of coronavirus disease 2019 (COVID-19). The "spike" or S protein facilitates viral entry into host cells.

22 Jun 2020

TPU researchers develop supersensitive sensors to detect enantiomers in drugs

Researchers of Tomsk Polytechnic University collaboratively with colleagues from the Czech Republic developed supersensitive sensors for detecting enantiomers, known as 'mirror molecules', in drugs.

19 Jun 2020

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

Cyclic peptide molecules of the fungal origin called cyclosporins were discovered in 1970's, and cyclosporin A soon became an important drug due to its immunosuppressive activity.

18 Jun 2020

NTU researchers develop a sustainable way to extract high-quality antimicrobial compounds

Scientists from Nanyang Technological University, Singapore have developed a sustainable and green way to extract high-quality antimicrobial compounds from seeds.

17 Jun 2020

Cobra and AstraZeneca sign supply agreement for manufacture of COVID-19 vaccine candidate

Cobra Biologics, part of the Cognate BioServices family, an international CDMO for biologics and pharmaceuticals, today announced it has signed a supply agreement with AstraZeneca UK Ltd. to provide GMP manufacture of the adenovirus vector-based COVID-19 vaccine candidate AZD1222, previously known as ChAdOx1 n-CoV-19.

From AstraZeneca 17 Jun 2020

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

An interview with Livia Eberlin, Assistant Professor at the University of Texas at Austin, discussing the development of mass-spectrometry based techniques for cancer diagnosis and improved clinical outcomes.

From Pittcon 16 Jun 2020

Sygnature Discovery supports New York Medical College pharmacologist in the fight against Covid-19

Sygnature Discovery, a leading independent integrated drug discovery and pre-clinical services company, is supporting Professor Sachin Gupte, a pharmacologist at the New York Medical College, in his endeavours to find a drug treatment for the lung damage that can result from Covid-19 infection.

From Sygnature Discovery Limited 15 Jun 2020

Determining Cannabinoids in Marijuana-Infused Edibles

Marijuana-infused edibles or medibles have increased immensely over the last 10 years. With products such as brownies and gummy bears infused with marijuana, it is more important now than ever to test these cannabis-related products.

From Pittcon 12 Jun 2020

Drug Discovery & Pharmaceuticals

A novel strategy to achieve site-selective chiral drug synthesis in living systems

Chemically engineered peptides could help fight persistent human health challenges

New steroid compounds from deep-water starfish show anticancer activity

GlobalData: Uncertainty during COVID-19 increases demand for immunity-boosting products

Academy of Finland funds projects for vaccine and drug development for COVID-19

Researchers investigate nelarabine drug for treating leukemia

New virtual incubator can catalyze early-stage drug discovery and development

UK announces research partnership with Atomwise to explore potential COVID-19 therapies

Chemist develops new drug to treat type 2 diabetes without undesired side effects

Jubilant Therapeutics announces preclinical data of dual LSD1 and HDAC6 inhibitor at AACR 2020

UQ superbug drug discoveries will be fast-tracked under international research deal

UAH researchers assess treatment efficacy of naturally occurring compounds against COVID-19

Researchers produce first fully-glycosylated full-length SARS-CoV-2 spike protein models

TPU researchers develop supersensitive sensors to detect enantiomers in drugs

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

NTU researchers develop a sustainable way to extract high-quality antimicrobial compounds

Cobra and AstraZeneca sign supply agreement for manufacture of COVID-19 vaccine candidate

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

Sygnature Discovery supports New York Medical College pharmacologist in the fight against Covid-19

Determining Cannabinoids in Marijuana-Infused Edibles

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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