Drug Discovery & Pharmaceuticals

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FlowSyn flow chemistry system enables economic and green manufacture of active pharmaceutical ingredients

Uniqsis has recently installed a 4-channel FlowSyn flow chemistry system in the Riley Research Group Laboratories at the University of Pretoria (South Africa).

From Uniqsis Ltd 6 Dec 2019

New method to improve skeleton of common chemicals

Every chemical, from the simplest to the most complex, have a structural skeleton of atoms. The atoms can be added or removed to transform the chemical into different types, for use in different applications. For many pharmaceutical and agricultural chemicals, the skeleton consists of a multi-membered carbon ring called a carbocycle.

5 Dec 2019

GW-led consortium receives $2.2 million from FDA for Biocompute Object Specification Project

A consortium led by the George Washington University (GW) has been refunded for their BioCompute Object Specification Project, thanks to a $2.2 million, five-year grant from the U.S. Food and Drug Administration.

4 Dec 2019

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

LUNAC Therapeutics, a UK based drug discovery company focused on the identification and development of advanced anticoagulants with minimal bleeding risk, today announced that, along with the Medicines Discovery Catapult and the University of Leeds, it has been awarded £3.14M funding under Innovate UK’s Biomedical Catalyst program.

4 Dec 2019

Metrion and LifeArc extend neuroscience-focused ion channel drug discovery collaboration

Metrion Biosciences Limited, the specialist ion channel CRO and drug discovery company, and LifeArc, a leading UK independent medical research charity, today announced an extension of their neuroscience-focused ion channel drug discovery collaboration, following the success of the initial twelve-month agreement.

From Metrion Biosciences Limited 4 Dec 2019

IONTAS, Adaptate Biotherapeutics join forces to generate and optimize antibodies for novel cancer targets

IONTAS Limited, a leader in the discovery and optimization of fully human antibodies, today announced it has entered into a collaboration agreement with Adaptate Biotherapeutics, developers of antibody-based therapeutics for modulation of gamma delta T-cells.

From FairJourney Biologics 4 Dec 2019

New screening method can rapidly discover potential cancer-treating compounds

Scientists at Scripps Research have developed a method for rapidly discovering potential cancer-treating compounds that work by resurrecting anti-tumor activity in immune cells called T cells.

3 Dec 2019

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

The growing trend of implementing immunotherapy into oncology has resulted in various new therapeutic cancer treatments utilizing antibodies.

From Sartorius 3 Dec 2019

ICR scientists carry out first comprehensive assessment of chemical probe resources

A new report urges biomedical researchers to use online web resources very carefully, taking into account their complementary benefits and weaknesses, when selecting small-molecule chemical probes to help answer their research questions.

28 Nov 2019

New technique could help produce uniform nanoparticles for use in drug delivery systems

A new technique in chemistry could pave the way for producing uniform nanoparticles for use in drug delivery systems.

27 Nov 2019

Validation of new method for studying how different drugs interact in the body

Scientists at Oregon State University may have proven how much people love coffee, tea, chocolate, soda and energy drinks as they validated their new method for studying how different drugs interact in the body.

26 Nov 2019

A large library of products derived from fungi could help find new drugs

An enormous library of products derived from more than ten thousand fungi could help us find new drugs.

26 Nov 2019

TARA's organ-on-a-chip technology can directly measure in vivo cardiac performance, study shows

TARA Biosystems, Inc. today reported in vivo and in vitro functional data from a study of investigational candidate, MYK-491, showing that TARA's human iPSC-derived organ-on-a-chip technology can directly measure in vivo cardiac performance.

18 Nov 2019

LUNAC announces spin out with £2.65 million funding to develop advanced anticoagulants

LUNAC Therapeutics today announced it has spun out of the University of Leeds with £2.65M funding in the first close of a Series A financing round.

15 Nov 2019

PhoreMost and Sentinel Oncology expand partnership to advance novel allosteric PLK1 inhibitor

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, and Sentinel Oncology, today announce an expansion of their collaboration to accelerate the progression of SOL686, a novel allosteric Polo-like kinase 1 (PLK1) inhibitor through preclinical development and IND enabling studies for the treatment of Glioma.

From PhoreMost 15 Nov 2019

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Turbine, a simulation-based drug discovery company today announced the closing of an institutional financing round led by Delin Ventures.

From Turbine Simulated Cell Technologies Ltd. 14 Nov 2019

Study provides new insight into antibiotic synthesis

Researchers at McGill University's Faculty of Medicine have made important strides in understanding the functioning of enzymes that play an integral role in the production of antibiotics and other therapeutics. Their findings are published in Science.

11 Nov 2019