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Study of safety issues surrounding the medical use of cannabis has just been launched

A first-of-its-kind study of safety issues surrounding the medical use of cannabis has just been launched. Known as the COMPASS study (Cannabis for the management of pain: assessment of safety study), the research initiative will follow 1400 chronic pain patients, 350 of whom use cannabis as part of their pain management strategy, for a one-year period.

8 Dec 2004

Shorter hospice enrollment was linked to elevated depression among family caregivers

Delayed enrollment in hospice can result in increased depression among family members after the death of their loved one, according to a study by Yale researchers published in the American Journal of Psychiatry.

8 Dec 2004

Clinical care of community-dwelling older adults with advanced chronic diseases would be enhanced by identifying and alleviating the range of symptoms they experience

In a study to determine the prevalence of a range of symptoms among older persons living independently with advanced chronic diseases, researchers at Yale have found that the majority experienced multiple moderate or severe symptoms.

8 Dec 2004

Greater risk of heart attack associated with Vioxx than Celebrex

In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a greater risk of heart attack associated with Vioxx than Celebrex, although neither of the two drugs showed a statistically significant elevated risk of heart attack relative to people who did not use the drugs.

8 Dec 2004

Study supports the use of the internal mammary artery in coronary artery bypass grafting

Long-term follow up with heart bypass patients treated in Veterans Affairs hospitals shows that 85 percent of left internal mammary artery grafts and 61 percent of vein grafts remain open (patent) after 10 years, and that these grafts are more likely to offer long-term success when they are attached to larger arteries on the heart, according to a new study in the Dec. 7, 2004 issue of the Journal of the American College of Cardiology.

8 Dec 2004

Noninvasive test of blood flow response may reveal early coronary disease

Chest pain patients who have abnormal coronary blood vessel function also have less responsive blood vessels in their fingertips, suggesting that a type of fingertip probe could become a useful screening tool, according to a new study in the Dec. 7, 2004 issue of the Journal of the American College of Cardiology.

8 Dec 2004

Leg wounds can be accurately assessed using photographs taken at a patient's home

A pilot study has shown that leg wounds can be accurately assessed using photographs taken at a patient's home, adding one more example to a growing list of medical conditions that can be successfully monitored remotely.

8 Dec 2004

Dermatologists recommend adding an E to the ABCD acronym for recognizing early melanomas

One more letter should be added to the alphabetic list of warning signs of melanoma, a potentially deadly skin cancer, according to a group of NYU School of Medicine dermatologists and their Australian colleagues.

8 Dec 2004

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical "brainscape" of neural activity across a living brain.

8 Dec 2004

Transplanted bone marrow cells reduce liver fibrosis in mice

Transplanted bone marrow cells can reduce carbon tetrachloride-induced liver fibrosis in mice and significantly improve their survival rates, according to a new study

8 Dec 2004

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

The prevalence of the disease varied significantly among ethnic groups. Hispanics had a higher prevalence than whites, while blacks had a lower prevalence than whites.

8 Dec 2004

Accumulated exposure to lead may be an important but unrecognized risk for developing cataracts in men

Lead continues to pose a significant public health problem in spite of substantial reductions in lead exposure in the United States in the recent past, according to background information in the article.

8 Dec 2004

Men and women who were overweight in young adulthood and middle age have significantly higher Medicare costs in older age

According to background information, obesity is associated with increased risk of high blood pressure, diabetes, and certain cancers, and has been identified as a major risk factor for coronary heart disease (CHD).

8 Dec 2004

Breast MRI moderately useful for detecting breast cancer

In women with breast lesions that are suspicious for cancer, based on clinical examination or mammography, performing a breast MRI has high sensitivity but only moderate specificity for detecting breast cancer, but does not necessarily eliminate the need for tissue sampling, according to a study in the December 8 issue of JAMA.

8 Dec 2004

Mexican Americans and non-Hispanic Whites born in the United States have a higher risk for developing psychiatric disorders

According to the results of a National Institutes of Health (NIH) study, reported in the December issue of the Archives of General Psychiatry, Mexican Americans and non-Hispanic Whites born in the United States have a higher risk for developing psychiatric disorders than their foreign-born counterparts who have immigrated to the United States.

7 Dec 2004

Zarnestra, a farnesyl transferase inhibitor, can help treat high-risk myelodysplastic syndrome patients

An oral targeted therapy gentle enough to be used by patients in their 70s or 80s is showing benefit in treating high-risk myelodysplastic syndrome (MDS), a pre-leukemic disorder that can progress to acute myelogenous leukemia (AML), according to a study presented at the annual meeting of the American Society of Hematology (ASH).

7 Dec 2004

Revlimid clinical data in newly diagnosed multiple myeloma presented

Celgene Corporation announced today that data evaluating clinical results on Revlimid (lenalidomide) as a new therapeutic approach for patients with newly diagnosed multiple myeloma (MM) was presented at the American Society of Hematology 46th Annual Meeting in San Diego.

7 Dec 2004

Combination of thalidomide and dexamethasone may be a promising treatment for multiple myeloma

The combination of two pills -- thalidomide and dexamethasone -- may be an effective alternative to the intravenous chemotherapy commonly prescribed to patients with multiple myeloma, according to a large collaborative study conducted by the Eastern Cooperative Oncology Group and led by a Mayo Clinic investigator.

7 Dec 2004

Study looks at muscle repair and resilience

Healthy military personnel and muscular dystrophy patients are at opposite ends of the spectrum when is comes to muscle strength and resilience. However, a new University of Iowa study may provide insights that improve muscle health for both these groups.

7 Dec 2004

Measuring bone marrow fat can better predict weakening of bones

BMD measurement with DEXA is presently the most commonly used parameter for determining bone weakening. Researchers have long questioned whether there may be other measurable bone components that influence mechanical stability of bone.

7 Dec 2004

Drug Trial News

Study of safety issues surrounding the medical use of cannabis has just been launched

Shorter hospice enrollment was linked to elevated depression among family caregivers

Clinical care of community-dwelling older adults with advanced chronic diseases would be enhanced by identifying and alleviating the range of symptoms they experience

Greater risk of heart attack associated with Vioxx than Celebrex

Study supports the use of the internal mammary artery in coronary artery bypass grafting

Noninvasive test of blood flow response may reveal early coronary disease

Leg wounds can be accurately assessed using photographs taken at a patient's home

Dermatologists recommend adding an E to the ABCD acronym for recognizing early melanomas

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Transplanted bone marrow cells reduce liver fibrosis in mice

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

Accumulated exposure to lead may be an important but unrecognized risk for developing cataracts in men

Men and women who were overweight in young adulthood and middle age have significantly higher Medicare costs in older age

Breast MRI moderately useful for detecting breast cancer

Mexican Americans and non-Hispanic Whites born in the United States have a higher risk for developing psychiatric disorders

Zarnestra, a farnesyl transferase inhibitor, can help treat high-risk myelodysplastic syndrome patients

Revlimid clinical data in newly diagnosed multiple myeloma presented

Combination of thalidomide and dexamethasone may be a promising treatment for multiple myeloma

Study looks at muscle repair and resilience

Measuring bone marrow fat can better predict weakening of bones

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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