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Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Combination immunotherapy as second or third line treatment extends overall survival to at least 15 months in patients with pleural malignant mesothelioma, according to late-breaking results from the MAPS2 trial presented today at the ESMO 2017 Congress in Madrid.

11 Sep 2017

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Rucaparib maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer by 77%, according to late-breaking results from the ARIEL3 trial reported today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Pembrolizumab has shown a promising response rate in patients with pretreated metastatic gastric cancer, according to late-breaking results from the KEYNOTE-059 trial presented today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Two new treatments may benefit patients with high risk prostate cancer, trial shows

Patients with high risk prostate cancer starting long-term hormone therapy may benefit from two new treatments, according to late-breaking results from the STAMPEDE trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

The superiority of docetaxel based triplet therapy over standard care in patients with resectable oesophago-gastric cancer has been confirmed in late-breaking results from the FLOT4 trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI trial, presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Eli Lilly to lay off 8.5 percent of employees in bid to cut costs

Eli Lilly and Company announced yesterday that they have decided to lay off around 8.5 percent of their employees. The company was on its way to develop two potential major drugs over the past year but set backs have led to major financial losses, leading to this decision.

7 Sep 2017

Study finds long-term effectiveness of HPV vaccine in preventing cervical cancer

A vaccine that can literally eradicate the majority of cervical cancer cases shows long-term effectiveness in a study published today in The Lancet.

6 Sep 2017

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

University of Arizona researchers are collaborating on a Phase 2 trial to determine whether a particular peptide administered before and after coronary bypass surgery mitigates or even reverses cognitive deficits thought to be connected to the procedure.

31 Aug 2017

New drug shows promise to treat women with estrogen positive metastatic breast cancer

Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease.

31 Aug 2017

First-in-class investigational drug lowers LDL cholesterol for up to one year, study finds

Inclisiran lowers low-density lipoprotein (LDL; "bad") cholesterol for up to one year in patients with high cardiovascular risk and elevated LDL cholesterol, according to late-breaking results from the ORION 1 trial presented today in a Hot Line LBCT Session at ESC Congress.

29 Aug 2017

Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

The United States Food and Drugs Administration FDA has granted permission for phase 3 trials in PTSD (Post traumatic stress disorder) patients using Ecstasy and psychotherapy in a treatment protocol called MDMA-Assisted Psychotherapy PTSD affects thousands of war veterans and other individuals and often leads to fatal outcomes of self-harm and suicides

28 Aug 2017

Drug reduces inflammation to lower cardiovascular disease and lung cancer risk

The IL-1β inhibitor canakinumab lowers the risk of cardiovascular disease and lung cancer risk by reducing inflammation, according to late-breaking results from the CANTOS trial presented today in a Hot Line - LBT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

SLU-led project receives NIH funding for clinical trial on potential treatment for MDR-TB

Saint Louis University is leading a multi-national clinical trial of what could become a regimen for drug resistant tuberculosis (TB) that does not require injectable medications. The project is funded by a $6.4 million task order from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

26 Aug 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

New clinical trial to test cancer drug in patients with advanced solid tumors

A clinical trial to test a new cancer drug in patients with advanced solid tumors, launches in four centers across the UK today (Wednesday), through Cancer Research UK's Center for Drug Development.

23 Aug 2017

Sanford Health launches solid tumor oncolytic virus clinical trial

Sanford Health is the first site in the United States to launch a clinical trial using a genetically-engineered virus that aims to destroy therapy-resistant tumors.

17 Aug 2017

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

The immunotherapy drug pembrolizumab has demonstrated a favorable safety profile and "promising durable clinical activity" in pretreated patients who exhibit high levels of the PD-L1 protein in advanced stages of small cell lung cancer (SCLC) – an aggressive form of the disease

16 Aug 2017

Small clinical trial shows promise for treating rare neurodegenerative disease

Results of a small clinical trial show promise for treating a rare neurodegenerative condition that typically kills those afflicted before they reach age 20.

11 Aug 2017

Drug Trial News

Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Two new treatments may benefit patients with high risk prostate cancer, trial shows

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Eli Lilly to lay off 8.5 percent of employees in bid to cut costs

Study finds long-term effectiveness of HPV vaccine in preventing cervical cancer

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

New drug shows promise to treat women with estrogen positive metastatic breast cancer

First-in-class investigational drug lowers LDL cholesterol for up to one year, study finds

Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

Drug reduces inflammation to lower cardiovascular disease and lung cancer risk

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

SLU-led project receives NIH funding for clinical trial on potential treatment for MDR-TB

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

New clinical trial to test cancer drug in patients with advanced solid tumors

Sanford Health launches solid tumor oncolytic virus clinical trial

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

Small clinical trial shows promise for treating rare neurodegenerative disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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