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NIH launches new study to test experimental vaccine that targets mosquito-transmitted diseases

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched a Phase 1 clinical trial to test an investigational vaccine intended to provide broad protection against a range of mosquito-transmitted diseases, such as Zika, malaria, West Nile fever and dengue fever, and to hinder the ability of mosquitoes to transmit such infections.

22 Feb 2017

Investigational malaria vaccine protects against multiple strains, study shows

An investigational malaria vaccine has protected a small number of healthy U.S. adults from infection with a malaria strain different from that contained in the vaccine, according to a study published today in the Proceedings of the National Academy of Sciences.

22 Feb 2017

Studies show benefits and risks of testosterone treatment in older men

It is commonly known that testosterone levels decrease as men age, but until last year, little was known about the effects of testosterone treatment in older men with low testosterone.

21 Feb 2017

Rapid patient recruitment and reduced trial costs: is LDS the answer?

LDS stands for Linked Database System, which essentially describes what it does. Our LDS technology uses multiple sources of information from hospitals, GPs and pharmacies. However in the future this information could also come from other health data sources e.g. your smartphone, Fitbit etc.

21 Feb 2017

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

The recent announcement that Merck is halting a Phase II/III study for a promising Alzheimer's treatment (verubecestat) was another setback in the continued and intensive effort to deliver an innovative therapy by 2020.

17 Feb 2017

Clinical trial to test potential new drug treatment for osteoarthritis

The University of Liverpool, in partnership with AKL Research and Development Ltd, is to lead on a clinical trial to test a potential new drug treatment for osteoarthritis.

16 Feb 2017

Sanford clinical study exploring immunotherapy drug to treat patients with advanced esophageal cancer

A clinical trial at Sanford Health is studying if an immunotherapy drug developed by Merck might be able to treat certain patients with advanced esophageal cancer. The Merck Keynote 181 trial is now open at Sanford.

31 Jan 2017

First-time drug trials launched on basis of flimsy, under-scrutinized evidence, say McGill researchers

Standards for authorizing first-time trials of drugs in humans are lax, and should be strengthened in several ways, McGill University researchers argue in a paper published today in Nature.

30 Jan 2017

ALCMI and Scancell collaborate to advance cancer vaccine clinical trials in NSCLC patients

The Addario Lung Cancer Medical Institute, the Bonnie J. Addario Lung Cancer Foundation and Scancell Holdings PLC today announce a collaboration to evaluate the use of Scancell's second innovative cancer vaccine, SCIB2, from its ImmunoBody platform to treat non-small cell lung cancer.

30 Jan 2017

New immunotherapy active against mucosal melanoma and improves survival for bladder cancer patients

Clinical trials of a new immunotherapy, pembrolizumab, have shown that it prolongs life significantly for patients with bladder cancer and is active against a rare sub-type of melanoma, called mucosal melanoma.

30 Jan 2017

Northwestern Medicine investigators to lead clinical trial for people with rare cancers

A novel national trial for people with no established alternative to treat their rare cancers is being co-led by Northwestern Medicine investigators, who helped conceive of and develop the project.

19 Jan 2017

New drug delivery system by Renishaw hopes to aid Parkinson’s treatment

Renishaw’s novel drug delivery system, to be used in partnership with Herantis Pharma Plc’s drug candidate CDNF for the treatment of Parkinson’s disease, is about to enter phase 1-2 clinical trials. The study will be supported by a €6 million grant from Horizon 2020, the European Union’s Framework Programme for Research and Innovation.

From Renishaw plc - Spectroscopy 12 Jan 2017

Ardelyx initiates two clinical trials to evaluate new treatment for hyperkalemia

Ardelyx, Inc., a clinical-stage company focused on enhancing the treatment of patients with gastrointestinal and cardiorenal diseases, today announced the initiation of a Phase 3 clinical trial and an onset-of-action clinical trial evaluating RDX7675 in patients with hyperkalemia, a potentially life-threatening condition common in patients with cardiorenal disease.

3 Jan 2017

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

FDA grants permission to assess safety of investigational drug for Alzheimer's disease in humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer's disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

28 Dec 2016

New study shows efficacy of Ebola vaccine in offering protection against disease

An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to a new study that included researchers from the University of Maryland School of Medicine.

26 Dec 2016

UF researchers play integral role in Ebola vaccine trial

An international group of researchers associated with the World Health Organization has published its final report on the Ebola vaccine trial in Guinea, finding that the vaccine is a safe and effective way to prevent Ebola infection.

26 Dec 2016

Experimental Ebola vaccine offers high protection against deadly virus, reveals major trial

An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to results published today in The Lancet. The vaccine is the first to prevent infection from one of the most lethal known pathogens, and the findings add weight to early trial results published last year.

23 Dec 2016

First large-scale clinical study of long-acting injectable HIV drug begins

The first large-scale clinical trial of a long-acting injectable drug for HIV prevention began today.

21 Dec 2016

Landmark clinical trial to test third investigational drug for Alzheimer's disease

An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer's disease.

20 Dec 2016

Drug Trial News

NIH launches new study to test experimental vaccine that targets mosquito-transmitted diseases

Investigational malaria vaccine protects against multiple strains, study shows

Studies show benefits and risks of testosterone treatment in older men

Rapid patient recruitment and reduced trial costs: is LDS the answer?

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

Clinical trial to test potential new drug treatment for osteoarthritis

Sanford clinical study exploring immunotherapy drug to treat patients with advanced esophageal cancer

First-time drug trials launched on basis of flimsy, under-scrutinized evidence, say McGill researchers

ALCMI and Scancell collaborate to advance cancer vaccine clinical trials in NSCLC patients

New immunotherapy active against mucosal melanoma and improves survival for bladder cancer patients

Northwestern Medicine investigators to lead clinical trial for people with rare cancers

New drug delivery system by Renishaw hopes to aid Parkinson’s treatment

Ardelyx initiates two clinical trials to evaluate new treatment for hyperkalemia

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

FDA grants permission to assess safety of investigational drug for Alzheimer's disease in humans

New study shows efficacy of Ebola vaccine in offering protection against disease

UF researchers play integral role in Ebola vaccine trial

Experimental Ebola vaccine offers high protection against deadly virus, reveals major trial

First large-scale clinical study of long-acting injectable HIV drug begins

Landmark clinical trial to test third investigational drug for Alzheimer's disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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