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First-in-class investigational drug lowers LDL cholesterol for up to one year, study finds

Inclisiran lowers low-density lipoprotein (LDL; "bad") cholesterol for up to one year in patients with high cardiovascular risk and elevated LDL cholesterol, according to late-breaking results from the ORION 1 trial presented today in a Hot Line LBCT Session at ESC Congress.

29 Aug 2017

Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

The United States Food and Drugs Administration FDA has granted permission for phase 3 trials in PTSD (Post traumatic stress disorder) patients using Ecstasy and psychotherapy in a treatment protocol called MDMA-Assisted Psychotherapy PTSD affects thousands of war veterans and other individuals and often leads to fatal outcomes of self-harm and suicides

28 Aug 2017

Drug reduces inflammation to lower cardiovascular disease and lung cancer risk

The IL-1β inhibitor canakinumab lowers the risk of cardiovascular disease and lung cancer risk by reducing inflammation, according to late-breaking results from the CANTOS trial presented today in a Hot Line - LBT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

SLU-led project receives NIH funding for clinical trial on potential treatment for MDR-TB

Saint Louis University is leading a multi-national clinical trial of what could become a regimen for drug resistant tuberculosis (TB) that does not require injectable medications. The project is funded by a $6.4 million task order from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

26 Aug 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

New clinical trial to test cancer drug in patients with advanced solid tumors

A clinical trial to test a new cancer drug in patients with advanced solid tumors, launches in four centers across the UK today (Wednesday), through Cancer Research UK's Center for Drug Development.

23 Aug 2017

Sanford Health launches solid tumor oncolytic virus clinical trial

Sanford Health is the first site in the United States to launch a clinical trial using a genetically-engineered virus that aims to destroy therapy-resistant tumors.

17 Aug 2017

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

The immunotherapy drug pembrolizumab has demonstrated a favorable safety profile and "promising durable clinical activity" in pretreated patients who exhibit high levels of the PD-L1 protein in advanced stages of small cell lung cancer (SCLC) – an aggressive form of the disease

16 Aug 2017

Small clinical trial shows promise for treating rare neurodegenerative disease

Results of a small clinical trial show promise for treating a rare neurodegenerative condition that typically kills those afflicted before they reach age 20.

11 Aug 2017

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Researchers at the University of Cincinnati begin a new clinical trial this fall, examining the potential role of a drug combination therapy to eliminate lymphangioleiomyomatosis (LAM) cells.

7 Aug 2017

Diabetes drug shows promise as Parkinson’s treatment

A drug commonly used to treat diabetes could help people living with Parkinson’s disease, say researchers.

7 Aug 2017

HIV prevention drug to be trialed by Britain's NHS

After a High Court case, an HIV prevention drug is soon to be available on the NHS. NHS England has issued a statement saying that pre-exposure prophylaxis (PrEP) treatment for HIV shall be available to an initial 10,000 people for a trial period of three years.

3 Aug 2017

Injectable ART may have same effectiveness as standard oral treatments

Antiretroviral therapy (ART) intramuscularly administered may have the same effectiveness as current oral treatments.

3 Aug 2017

Biologic substance APOSEC shows promise for healing dermal wounds

APOSEC is a substance obtained from white blood corpuscles and was developed by a research group led by thoracic surgeon Hendrik Jan Ankersmit, Head of the Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration at MedUni Vienna.

3 Aug 2017

FDA gives its nod to new drug Imbruvica (Ibrutinib) for chronic Graft versus Host Disease

The U.S. Food and Drug Administration (FDA) yesterday in a press release informed about the approval of Imbruvica (ibrutinib) for the treatment of adult patients with chronic graft versus host disease (cGVHD) who have previously failed with one or more treatment. This is the first drug that the FDA has given its approval to in this disease condition.

2 Aug 2017

$New drug Idhifa for patients with refractory acute myeloid leukemia (AML) gets FDA nod$

New drug Idhifa for patients with refractory acute myeloid leukemia (AML) gets FDA nod

The U.S. Food and Drug Administration (FDA) in a statement yesterday reported its approval for a new drug, Idhifa (enasidenib) for the treatment of acute myeloid leukemia (AML) in adults that has either relapsed or is refractory to standard chemotherapy.

2 Aug 2017

Type 1 diabetes clinical trial reaches halfway point for enrollment and treatment

The Sanford Project: T-Rex Study, a Phase 2 clinical trial conducted collaboratively by Sanford Health and Caladrius Biosciences, Inc., has reached the halfway point for enrollment and treatment.

28 Jul 2017

New trial shows ketamine's effectiveness to treat geriatric depression

Australian researchers have completed the world's first randomised control trial (RCT) assessing the efficacy and safety of ketamine as a treatment for depression in elderly patients.

24 Jul 2017

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

A Food and Drug Administration (FDA) panel created history by recommending a gene therapy for patients with cancer. In this therapy the patient’s own genes would be modified to fight the cancer cells. The patient’s cells which are thus altered to treat the cancer would thus be termed as “living drugs” as they act as soldiers to treat the cancer. These cells boost up the immune system and help the body fight the cancer.

14 Jul 2017

Drug Trial News

First-in-class investigational drug lowers LDL cholesterol for up to one year, study finds

Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

Drug reduces inflammation to lower cardiovascular disease and lung cancer risk

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

SLU-led project receives NIH funding for clinical trial on potential treatment for MDR-TB

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

New clinical trial to test cancer drug in patients with advanced solid tumors

Sanford Health launches solid tumor oncolytic virus clinical trial

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

Small clinical trial shows promise for treating rare neurodegenerative disease

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Diabetes drug shows promise as Parkinson’s treatment

HIV prevention drug to be trialed by Britain's NHS

Injectable ART may have same effectiveness as standard oral treatments

Biologic substance APOSEC shows promise for healing dermal wounds

FDA gives its nod to new drug Imbruvica (Ibrutinib) for chronic Graft versus Host Disease

New drug Idhifa for patients with refractory acute myeloid leukemia (AML) gets FDA nod

Type 1 diabetes clinical trial reaches halfway point for enrollment and treatment

New trial shows ketamine's effectiveness to treat geriatric depression

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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