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Clinical trial investigates osteoporosis medication for type 1 diabetes

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States and a top research center for diabetes and other life-threatening illnesses, is leading a phase 1/2 clinical trial investigating an osteoporosis medication as a way to improve beta cell health in people with early type 1 diabetes.

19 Mar 2025

ASCOLT trial explores aspirin’s role in preventing colorectal cancer recurrence

A large-scale, international, multicentre, phase 3 clinical trial of aspirin for the secondary prevention of colorectal cancer has concluded.

17 Mar 2025

Clinical trial of vaccine candidate to prevent Lassa fever begins enrollment

A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.

17 Mar 2025

Adding chemotherapy to radiotherapy does not improve outcomes for cervical cancer patients

Results from the NRG Oncology GOG-0263 phase III clinical trial testing the addition of cisplatin-based chemotherapy to adjuvant radiotherapy following radical hysterectomy and lymphadenectomy for patients with early-stage, intermediate-risk cervical carcinoma indicated that the addition of chemotherapy did not improve outcomes for patients and led to increased toxicity for patients.

14 Mar 2025

Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston

A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer's disease is underway at UTHealth Houston.

14 Mar 2025

Clinical trial tests herpes virus-based therapy for neurogenic bladder in people with spinal cord injury

A modified herpes virus that targets spinal cord nerve cells to treat neurogenic bladder in people with spinal cord injury is underway in a first-in-human clinical trial by UTHealth Houston at TIRR Memorial Hermann.

12 Mar 2025

Oral antiviral drug proves successful in preventing symptomatic COVID-19 in household members

An international clinical trial has identified a medication that can help prevent symptomatic COVID-19 in people exposed within households.

12 Mar 2025

Tecovirimat monotherapy found ineffective for treating clade II mpox in NIH-sponsored trial

NIH-sponsored trial data offer further evidence to help inform mpox treatment decisions.

12 Mar 2025

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

A real-world study of over 4,000 US patients without type 2 diabetes found that those who persisted with Tirzepatide for at least six months lost an average of 12.9% of their body weight. The study highlights Tirzepatide’s potential as an effective off-label obesity treatment before its formal FDA approval for weight loss.

11 Mar 2025

Next-generation, inhaled COVID-19 vaccine enters phase-2 clinical trial

Researchers at McMaster University have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine.

10 Mar 2025

Eradivir begins Phase 2 challenge study for antiviral therapeutic EV25

Eradivir, a clinical-stage small molecule immunotherapy biotech company, announced it has begun a Phase 2 challenge study with its antiviral therapeutic, EV25. The study will provide safety and efficacy data gathered from otherwise healthy participants infected with influenza then later treated with EV25.

7 Mar 2025

Breakthrough drug more than doubles survival in glioblastoma patients

A drug developed at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has been shown to extend survival for patients with glioblastoma, the most common primary brain tumor in adults.

7 Mar 2025

Phase 1 trial examines safety and feasibility of stem cell treatment for Parkinson's

A recently launched Phase 1 clinical trial at Mass General Brigham is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson's disease in which a patient's stem cells are reprogrammed to replace dopamine cells in the brain damaged by the disease.

6 Mar 2025

New clinical trial aims to optimize pain management and reduce opioid use after mastectomy

A multidisciplinary team of University of Cincinnati Cancer Center researchers is leading a new clinical trial aimed to optimize pain management and reduce the need for opioids after mastectomy procedures.

6 Mar 2025

Stem cell therapy for cornea injuries demonstrates remarkable results in clinical trial

An expanded clinical trial that tested a groundbreaking, experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients who were treated and followed for 18 months, and there was a high proportion of complete or partial success.

4 Mar 2025

Omalizumab outperforms oral immunotherapy in treating multi-food allergy

A clinical trial has found that the medication omalizumab, marketed as Xolair, treated multi-food allergy more effectively than oral immunotherapy (OIT) in people with allergic reactions to very small amounts of common food allergens.

2 Mar 2025

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the cholesterol drug fenofibrate (Triglide, Fibricor, Lipofen) as an investigational and potential treatment for patients with HPV+ cervical and HPV+ head and neck cancer (HNSCC).

28 Feb 2025

Drug may offer new hope for preventing migraines in kids and teens

For children and teens living with migraine, there may be a new preventive treatment, according to a preliminary study released today, February 26, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

26 Feb 2025

Scientists pioneer fecal transplant capsules to enhance pancreatic cancer treatment

Scientists at Lawson Research Institute (Lawson) of St. Joseph's Health Care London and London Health Sciences Centre Research Institute (LHSCRI) are the first in the world to study fecal transplants using capsules containing microbes from the gut of healthy volunteers to improve the response of patients with advanced pancreatic cancer to chemotherapy.

26 Feb 2025

New drug ataciguat shows promise for managing aortic valve stenosis

Aortic valve stenosis (AVS) is a significant health concern affecting over 1.5 million Americans and millions more globally.

24 Feb 2025

Drug Trial News

Clinical trial investigates osteoporosis medication for type 1 diabetes

ASCOLT trial explores aspirin’s role in preventing colorectal cancer recurrence

Clinical trial of vaccine candidate to prevent Lassa fever begins enrollment

Adding chemotherapy to radiotherapy does not improve outcomes for cervical cancer patients

Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston

Clinical trial tests herpes virus-based therapy for neurogenic bladder in people with spinal cord injury

Oral antiviral drug proves successful in preventing symptomatic COVID-19 in household members

Tecovirimat monotherapy found ineffective for treating clade II mpox in NIH-sponsored trial

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

Next-generation, inhaled COVID-19 vaccine enters phase-2 clinical trial

Eradivir begins Phase 2 challenge study for antiviral therapeutic EV25

Breakthrough drug more than doubles survival in glioblastoma patients

Phase 1 trial examines safety and feasibility of stem cell treatment for Parkinson's

New clinical trial aims to optimize pain management and reduce opioid use after mastectomy

Stem cell therapy for cornea injuries demonstrates remarkable results in clinical trial

Omalizumab outperforms oral immunotherapy in treating multi-food allergy

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

Drug may offer new hope for preventing migraines in kids and teens

Scientists pioneer fecal transplant capsules to enhance pancreatic cancer treatment

New drug ataciguat shows promise for managing aortic valve stenosis

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

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