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Smoking during pregnancy increases risk of having a child with missing fingers and toes

In the largest study of its kind, plastic surgeons found smoking during pregnancy significantly elevates the risk of having a child with excess, webbed or missing fingers and toes, according to the January issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

6 Jan 2006

Exposure to infections at birth can trigger brain damage and the development of cerebral palsy

Exposure to certain viral infections shortly before and after birth (the perinatal period) is associated with cerebral palsy, finds a study published online by the British Medical Journal.

6 Jan 2006

Cyclosporine suppresses hepatitis C virus and increases the chance of a sustained virological response after liver transplantation

Liver transplant patients with hepatitis C virus (HCV) achieved significantly better long-term viral response when taking the immunosuppressive agent Cyclosporine along with interferon-ribavirin combination therapy. Cyclosporine also showed efficacy against Hepatitis C virus in vitro.

5 Jan 2006

New pathways linking liver disease to changes in the central nervous system

Liver disease is often associated with "sickness behaviors," such as malaise, listlessness, anorexia, difficulty concentrating, and fatigue. In cholestatic liver diseases (where bile production is impaired) such as primary biliary cirrhosis, fatigue occurs in up to 86 percent of patients.

5 Jan 2006

Limitation of combination therapy of Interferon and Ribavirin for older patients with chronic hepatitis C

A new Japanese study examining the effects of combination therapy on older patients with hepatitis C found more adverse effects necessitating discontinuation of treatment, lowering of dosages, and lower long-term benefits in this age group.

5 Jan 2006

Herceptin may work better when it is followed by injections of interleukin

A new study suggests that antibody-based cancer drugs might help patients more if they are given with substances that stimulate the immune system.

5 Jan 2006

Children more likely to survive in-hospital cardiac arrests than adults

Children are more likely to survive in-hospital cardiac arrests than adults and with appropriate cardiopulmonary resuscitation (CPR), the survival rates for both children and adults are higher than previously thought.

5 Jan 2006

Elevated homocysteine levels may be a biomarker for increased risk of AMD

People who have elevated homocysteine in their blood, an amino acid that is a known biomarker for cardiovascular disease, may also be at an increased risk of developing age-related macular degeneration (AMD), according to a study in the January issue of the American Journal of Ophthalmology.

5 Jan 2006

Exercise helps elderly heal

The body's ability to heal even small skin wounds normally slows down as we age. But a new study in older adults finds that regular exercise may speed up the wound-healing process by as much as 25 percent.

5 Jan 2006

NEJM rotavirus studies: statement by PATH's Rotavirus Vaccine Program

On Thursday, January 5, the New England Journal of Medicine published the results of two important clinical trials of rotavirus vaccines.

4 Jan 2006

Reduced rates of lung function decline in cystic fibrosis clinical study patients

Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period.

2 Jan 2006

Brain volume may be used as an early detection system for dementia

Reduced volume, or atrophy, in parts of the brain known as the amygdala and hippocampus may predict which cognitively healthy elderly people will develop dementia over a six-year period, according to a study in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Jan 2006

Treatments for epilepsy compared

In a comprehensive analysis and mathematical model of the available scientific data, researchers at the University of York on behalf of the National Institute of Health and Clinical Excellence (NICE) in the United Kingdom found that newer drugs used to treat the most common forms of epilepsy are more expensive than older drugs, but produce similar health benefits.

30 Dec 2005

University of Michigan Medical School to study the science of obesity and metabolism

As millions of Americans prepare their New Year’s resolutions to lose weight, eat better or exercise more, the University of Michigan Medical School is launching a new center that may help explain why so many resolutions fail, while others succeed.

29 Dec 2005

Hyperbaric oxygen treatments mobilizes stem cells aiding injury repair

According to a study to be published in the American Journal of Physiology-Heart and Circulation Physiology, a typical course of hyperbaric oxygen treatments increases by eight-fold the number of stem cells circulating in a patient's body.

29 Dec 2005

Misdosing anti-clotting drugs leads to heart attack symptoms

Because of inaccuracies in prescribing, 42 percent of patients rushed to emergency rooms with symptoms of a heart attack received doses of powerful drugs intended stop clotting in coronary arteries outside of the recommended range, a new analysis by Duke Clinical Research Institute (DCRI) cardiologists has found.

28 Dec 2005