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LABA medications, asthma and inhaled steroids

A combination of airway-opening drugs and inhaled inflammation-reducing steroids works better at preventing severe asthma attacks than a normal dose of steroids alone, according to a new review of recent studies.

18 Oct 2005

Access to genetic counseling and testing are an important part of cancer control

Ten years after the identification of the first breast cancer susceptibility genes so few high-risk minority women have received genetic counseling or testing that the standard methods of calculating risk have not been validated in these groups and the results of genetic testing can still produce surprises.

18 Oct 2005

Data supports use of personal and family history of breast cancer, ovarian cancer, or both in making clinical decisions

African American women at high-risk of breast cancer have genetic mutations that would make genetic testing feasible, according to a study in the October 19 issue of JAMA: The Journal of the American Medical Association.

18 Oct 2005

Intensity modulated radiation therapy (IMRT) for head and neck cancer

Results from a University of Pittsburgh study evaluating intensity modulated radiation therapy (IMRT) for head and neck cancer determined the ideal doses for lessening treatment side effects. The findings were presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver.

18 Oct 2005

Interactive health websites can help people live with their chronic illness

Contrary to the UCL group's original findings, the review - published by the Cochrane Library and revised after being found to contain errors - shows that people who use interactive health programs and websites generally have a better health outcome than non-users.

18 Oct 2005

HIV drug combo Trimethoprim-sulfamethoxazole highly effective at preventing malaria

A drug combination used to prevent pneumonia and opportunistic bacterial infection in persons with HIV/AIDS has unexpectedly been found to be highly effective at preventing malaria, according to a study published in the November 15 issue of The Journal of Infectious Diseases, now available online.

18 Oct 2005

Possible new combination treatment regimen for patients with head and neck cancers who develop a second tumor

Few treatment options exist for patients with head and neck cancers who develop a second tumor or whose disease recurs in an area that has previously received radiation. Data from an international study reveal a possible new combination treatment regimen that offers a significant survival advantage for many of these patients.

18 Oct 2005

Treating four or more brain tumors in a single radiosurgery session resulted in improved survival

...compared to whole brain radiation therapy alone, according to a study the University of Pittsburgh School of Medicine presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver.

18 Oct 2005

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

Correcting the timing of heart contractions through cardiac resynchronization therapy can be a lifesaver for people with advanced heart failure. But the procedure, as it is done today, fails in about 15 percent of patients.

18 Oct 2005

No credible evidence behind claims of harm from the MMR vaccination

There was no credible evidence behind claims of harm from the MMR vaccination. This is the conclusion drawn by the Cochrane Review Authors, an international team of researchers, after carefully drawing together all of the evidence found in 31 high quality studies from around the world.

18 Oct 2005

Beta blockers not as effective as other drugs that reduce high blood pressure in patients with hypertension

Beta blockers are not as effective as other drugs that reduce high blood pressure in patients with hypertension, concludes a meta-analysis published online by The Lancet.

18 Oct 2005

Pathological liars found to have less gray matter

In a new study Dr. Adrian Raine and Yaling Yang of the University of Southern California, and colleagues found that individuals who habitually lied and cheated had less gray matter and more white matter in their prefrontal cortex than normal people.

18 Oct 2005

More doubt cast on benefit of beta blockers for high blood pressure

A comprehensive study has produced more evidence that a drug widely used to treat high blood pressure may not be the best option for many patients.

18 Oct 2005

Women with cervical cancer have a broad range of concerns

A recent study in the International Journal of Gynecological Cancer revealed that women with cervical cancer have a broad range of concerns regarding cervical cancer, its treatment and additional psychosocial issues, including but not limited to sexuality, and that their male partners had equal levels of concerns in the first year following treatment, contrary to beliefs that the types or intensities of concerns between the two may differ.

17 Oct 2005

Corticosteroids often used in the treatment of infectious mononucleosis

Corticosteroids are used often in the treatment of infectious mononucleosis, and for reasons beyond usual criteria, according to a study in the October issue of Archives of Otolaryngology–Head & Neck Surgery.

17 Oct 2005

Study shows possibilities for curing patients with early-stage Hodgkin's lymphoma of their cancer

Doctors in Germany have determined that patients suffering from early-stage Hodgkin's lymphoma can receive a reduced dose of involved field radiation therapy, combined with chemotherapy, and still retain a high survival rate, according to a study presented October 17, 2005, at the American Society for Therapeutic Radiology and Oncology's 47th Annual Meeting in Denver.

17 Oct 2005

New approaches to counteract platelet shortages

Availability of safe platelets is a fundamental blood transfusion challenge and can be especially problematic in times of emergency. Several studies presented at the annual American Association of Blood Banks (AABB) meeting today demonstrate new approaches to counteract platelet shortages by enhancing the safety of whole blood derived platelets, precluding the need to rely on only those obtained through apheresis.

17 Oct 2005

Study identifies molecular switch that integrates cell survival signals from multiple intracellular signaling pathways

The finding has substantial clinical significance, as mutations in these cell survival-signaling pathways are associated with many human cancers, and a better understanding of how these pathways converge to regulate the delicate balance between cell proliferation and cell death may lead to development of more effective cancer therapies.

17 Oct 2005

Study of the molecular mechanism involved in the human implantation process

In spite of advances in assisted reproductive technologies, more than 6.1 million women in the United States - roughly 20 percent of all women of reproductive age - suffer from infertility.

17 Oct 2005

Treating breast cancer with "MammoSite" study

Treating breast cancer with MammoSite resulted in a low risk of complications and was generally well tolerated, according to a University of Pittsburgh School of Medicine study presented today at the 47th annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver.

17 Oct 2005

Drug Trial News

LABA medications, asthma and inhaled steroids

Access to genetic counseling and testing are an important part of cancer control

Data supports use of personal and family history of breast cancer, ovarian cancer, or both in making clinical decisions

Intensity modulated radiation therapy (IMRT) for head and neck cancer

Interactive health websites can help people live with their chronic illness

HIV drug combo Trimethoprim-sulfamethoxazole highly effective at preventing malaria

Possible new combination treatment regimen for patients with head and neck cancers who develop a second tumor

Treating four or more brain tumors in a single radiosurgery session resulted in improved survival

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

No credible evidence behind claims of harm from the MMR vaccination

Beta blockers not as effective as other drugs that reduce high blood pressure in patients with hypertension

Pathological liars found to have less gray matter

More doubt cast on benefit of beta blockers for high blood pressure

Women with cervical cancer have a broad range of concerns

Corticosteroids often used in the treatment of infectious mononucleosis

Study shows possibilities for curing patients with early-stage Hodgkin's lymphoma of their cancer

New approaches to counteract platelet shortages

Study identifies molecular switch that integrates cell survival signals from multiple intracellular signaling pathways

Study of the molecular mechanism involved in the human implantation process

Treating breast cancer with "MammoSite" study

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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