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Study explores interplay between bone, adrenal glands, and aging

Figuring out how the tissues in our bones, adrenal glands, muscle and fat "talk" to each other could help scientists better understand what happens to our skeletons with age, when our bones tend to lose mass and become weaker, leaving us at risk for falls and fractures.

1 Aug 2024

Novel anti-tuberculosis compound targets bacterial membrane protein

Researchers from Heinrich Heine University Düsseldorf (HHU) and the University of Duisburg-Essen (UDE) have together succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. In the scientific journal Cell Chemical Biology, they describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.

1 Aug 2024

New treatment option for endometrial cancer shows promise in phase II trial

The latest trial of a new antibody drug that delivers potent chemotherapy directly to cancer cells for patients with advanced or recurrent endometrial cancer moves ahead to be studied further in a phase III trial.

1 Aug 2024

Geographic analysis pinpoints areas for improved colorectal cancer screening in Hispanic/Latino populations

Cleveland Clinic-led research has identified geographic areas in the United States where strategic efforts to promote colorectal cancer screening could help reduce healthcare gaps affecting Hispanic/Latino communities.

1 Aug 2024

Study reveals deepening mistrust in healthcare providers post-COVID

A cross-representative survey of adults in the United States showed decreasing levels of trust in physicians and hospitals during the COVID-19 pandemic-;and the lower the trust, the less likely an individual was to get vaccinated against SARS-CoV-2 or influenza. The findings come from a survey study of more than 400,000 U.S. adults published in JAMA Network Open by a team co-led by investigators at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system.

1 Aug 2024

Scientists capture NMDAR protein's 'twist' motion, key to brain signaling

Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains. One wrong step can lead to a range of neurological disorders. NMDAR binds to the neurotransmitter, glutamate, and another compound, glycine. These bindings control NMDAR's dance steps. When their routine is over, the NMDAR opens. This open ion channel generates electrical signals critical for cognitive functions like memory.

1 Aug 2024

Microbes play key role in carcinogenesis

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world. This includes – as shown in a new study by EMBL researchers and collaborators at the University of Split, Croatia – the way the body responds to carcinogens and develops cancer.

1 Aug 2024

New study reveals sweet spot for muscle growth

When performing resistance training such as lifting weights, there's a lot of interest in how close you push yourself to failure – the point where you can't do another rep – and how it affects your results.

1 Aug 2024

COVID vaccines shown to reduce risk of arterial thrombosis

A new study, published today in Nature Communications and involving nearly the whole adult population of England, has found that the incidence of heart attacks and strokes was lower after COVID-19 vaccination than before or without vaccination.

1 Aug 2024

AI unlocks potential of antimicrobial peptides for new antibiotics

In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers at The University of Texas at Austin have leveraged artificial intelligence to develop a new drug that already is showing promise in animal trials.

1 Aug 2024

Medline to offer first ever FDA-cleared, point-of-care fentanyl urine screening kit on RYAN™ analyzer

Carolina Liquid Chemistries Corp. (CLC) has entered into a distribution agreement with Medline Industries, LP (Medline) to make the first ever FDA-cleared, point-of-care fentanyl screening test kit readily available to many point-of-care sites and clinical laboratories across the United States of America.

1 Aug 2024

High blood pressure risk elevated by tellurium contaminant in foods

The likelihood of developing high blood pressure (hypertension) increases with higher levels of tellurium, a contaminant transferred from mining and manufacturing activities to foods.

31 Jul 2024

Nine months of joint replacement surgery lost due to COVID-19, study reveals

Nearly nine months of joint replacement surgery has been lost - around 160,000 fewer operations - since the start of the COVID-19 pandemic, a new study led by the University of Bristol has found.

31 Jul 2024

Study reveals £4bn savings potential from dementia risk reduction interventions

Public health interventions that tackle dementia risk factors could yield as much as £4bn in savings in England by reducing dementia rates and helping people to live longer and healthier, finds a new study led by UCL researchers.

31 Jul 2024

BYU researchers develop first national glycemic index database for U.S. diets

Karen Della Corte, BYU nutrition and dietetics professor, recently authored a new study, published in The American Journal of Clinical Nutrition, that developed a national glycemic index (GI) and glycemic load (GL) database to offer insights into the evolving quality of carbohydrates consumed in the United States, something that hadn't been done previously.

31 Jul 2024