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Rare but real: The neurological risks associated with vaccines

Review highlights the rare neurological risks associated with vaccination, emphasizing the importance of accurate detection and management strategies, particularly in the context of the COVID-19 pandemic.

9 Aug 2024

AI unlocks secrets of gastric cancer development

Gastric cancer, a significant global health challenge, is characterized by a complex transition from inflammation-induced premalignant lesions to malignancy. The quest for early diagnosis and prevention is impeded by the intricate biological shifts that mark this journey, highlighting an urgent need for a deeper dive into the underlying the multi-level and dynamic features.

8 Aug 2024

Discovery of progenitor exhausted T cells offers hope for cancer patients

Tumor immunotherapy leverages the body's immune system to target and eradicate cancer cells, offering a crucial treatment for patients unresponsive to surgery or conventional therapies. Despite its potential, the effectiveness of immunotherapy is often hindered by T cell exhaustion within the tumor microenvironment, leading to diminished immune response and tumor progression. Based on these challenges, exploring the role of progenitor exhausted T cells (Tpex) in overcoming immune resistance is essential for advancing immunotherapeutic strategies and improving clinical outcomes.

8 Aug 2024

Advanced MRI scans could predict persistent symptoms in concussion patients

Offering patients with concussion a type of brain scan known as diffusion tensor imaging MRI could help identify the one in three people who will experience persistent symptoms that can be life changing, say Cambridge researchers.

8 Aug 2024

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

Research identifies cross-reactive T cells targeting both SARS-CoV-2 and human SNX8 protein, providing insights into the autoimmune mechanisms driving MIS-C in children.

8 Aug 2024

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological processes in cells.

8 Aug 2024

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

A new research paper was published in Oncotarget's Volume 15 on August 5, 2024, entitled, "Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival."

8 Aug 2024

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

A traumatic brain injury, or TBI, is caused by a contusion to the head that may result in injury to the brain.

8 Aug 2024

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.

8 Aug 2024

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University of Texas Health Science Center at San Antonio (UT Health San Antonio).

8 Aug 2024

American College of Cardiology releases updated guidance on managing patients hospitalized for heart failure

The American College of Cardiology has issued updated guidance on managing patients hospitalized for heart failure (HF) to provide a decision-making pathway that tailors therapy to clinical trajectory to better manage disease.

8 Aug 2024

School reopenings during COVID-19 linked to spike in youth mental health emergencies, study finds

Study found that school reopenings after COVID-19 closures in Italy led to a significant rise in youth psychiatric emergencies, particularly among females, highlighting the mental health impact of returning to academic and social pressures.

8 Aug 2024

Bran-enriched corn flour lowers LDL cholesterol in adults with elevated levels, study finds

Study found that bran-enriched corn flour significantly reduces LDL cholesterol levels in adults with elevated cholesterol, while having minimal impact on gut microbiota composition.

8 Aug 2024

$Poor physical function, not bone density, drives higher fracture risk in older women with type 2 diabetes$

Poor physical function, not bone density, drives higher fracture risk in older women with type 2 diabetes

Study indicates that older women with type 2 diabetes have a higher risk of fractures primarily due to impaired physical function rather than reduced bone density, despite stronger bone structure.

8 Aug 2024

Low-acid diets with fruits and vegetables significantly improve kidney and heart health in hypertension patients

Study found that low-acid diets, particularly those rich in fruits and vegetables, offer significant kidney and cardiovascular protection in patients with primary hypertension, outperforming traditional medical care.

8 Aug 2024

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) announced today a new research grant awarded to Daniela C. Zarnescu, Ph.D., Professor of Cellular and Molecular Physiology at Penn State University College of Medicine, in collaboration with Jon Njardarson, Ph.D., Professor at the University of Arizona.

8 Aug 2024

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Researchers at Columbia University Mailman School of Public Health, the University of North Carolina at Chapel Hill and at the National Academy of Sciences of Ukraine used the setting of the man-made Ukrainian Holodomor famine of 1932-1933 to examine the relation between prenatal famine and adult Type 2 diabetes mellitus (T2DM).

8 Aug 2024

Cannabis dependence associated with increased occurrence of head and neck cancer

A study from the USC Head and Neck Center, part of Keck Medicine of USC and the USC Caruso Department of Otolaryngology – Head and Neck Surgery, suggests that cannabis, the most commonly used illicit substance worldwide, is associated with an increased occurrence of head and neck cancer.

8 Aug 2024

Gene activity can predict severe side effects from melanoma treatment

An activity pattern in certain genes responsible for building proteins known as spleen tyrosine kinases can predict which melanoma patients are likely to have severe side effects from immunotherapy designed to treat the most deadly skin cancer, a new study shows.

8 Aug 2024

New insights into the role of cancer-associated fibroblasts in promoting lymphatic metastasis

Lymph node metastasis is a crucial factor in cancer progression, significantly affecting patient prognosis and treatment outcomes.

8 Aug 2024

Medical Condition News

Rare but real: The neurological risks associated with vaccines

AI unlocks secrets of gastric cancer development

Discovery of progenitor exhausted T cells offers hope for cancer patients

Advanced MRI scans could predict persistent symptoms in concussion patients

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

American College of Cardiology releases updated guidance on managing patients hospitalized for heart failure

School reopenings during COVID-19 linked to spike in youth mental health emergencies, study finds

Bran-enriched corn flour lowers LDL cholesterol in adults with elevated levels, study finds

Poor physical function, not bone density, drives higher fracture risk in older women with type 2 diabetes

Low-acid diets with fruits and vegetables significantly improve kidney and heart health in hypertension patients

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Cannabis dependence associated with increased occurrence of head and neck cancer

Gene activity can predict severe side effects from melanoma treatment

New insights into the role of cancer-associated fibroblasts in promoting lymphatic metastasis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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