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Genetic and molecular risk factors discovered for subsequent stroke and MACE

People who experience an arterial ischemic stroke (AIS) or transient ischemic stroke (TIA) are at an increased risk of suffering a second stroke or other major adverse cardiovascular event (MACE), making it critically important to identify risk factors and treatments to prevent these subsequent occurrences.

22 Jul 2024

Study reveals age-related differences in amputation rates following PAD surgery

People in their 50s with severe peripheral artery disease or PAD may be more likely than people in their 80s to undergo leg amputation one to five years after emergency surgery to restore blood flow to the lower limbs, according to new research published today in the American Heart Association's flagship journal Circulation.

22 Jul 2024

Research shows the ability of proteins to predict onset of many diverse diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

22 Jul 2024

Innovative genetic approaches to rare disease diagnosis

The majority of rare diseases have a genetic cause. The underlying genetic alteration can be found more and more easily, for example by means of exome sequencing (ES), leading to a molecular genetic diagnosis.

22 Jul 2024

Brain coupling patterns as predictive markers for psychosis in 22q11.2DS

A UNIGE team shows that overly strong or weak interconnections between certain brain areas could be a predictive marker of the disease.

22 Jul 2024

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications.

22 Jul 2024

Empowering human intelligence: Strategies for healthy aging and memory

People can reduce their risk of age-related dementia by exercising their brains properly instead of Googling, according to a leading Canadian academic.

22 Jul 2024

Challenges and opportunities in rare tumor research

Ning Li et al., at Chinese Academy of Medical Sciences and Peking Union Medical College, China, provides a comprehensive review on the challenges and opportunities in the field of rare tumor research and management.

22 Jul 2024

Living near greenspace in midlife tied to slower cognitive decline in older age

The association between midlife residential greenness and cognitive decline.

22 Jul 2024

Could taking vinegar every day help reduce depression?

In a recent study, daily vinegar ingestion significantly improved depression scores in overweight, healthy adults over four weeks, potentially due to enhanced niacin metabolism.

21 Jul 2024

Australian welders exposed to high levels of dangerous cancer-causing fumes, study reveals

New Curtin University research has revealed at least 46,000 Australian welders are exposed to high levels of dangerous, potentially cancer-causing fumes at work -; and little is being done to protect them.

21 Jul 2024

Study finds limited evidence for massage therapy's effectiveness in pain relief

A study in JAMA Network Open reviews evidence on massage therapy's effectiveness in relieving pain, finding moderate certainty for some conditions but overall low certainty for most.

21 Jul 2024

Concussions in retired rugby players linked to higher neurodegenerative disease biomarkers

A study in the International Journal of Molecular Sciences reveals that retired rugby players with a history of concussions exhibit significant differences in biomarkers associated with neurodegenerative diseases compared to non-contact sports participants.

21 Jul 2024

AI and imaging advances revolutionize multiple sclerosis diagnosis

A study in Translational Vision Science & Technology reveals that integrating AI with IR-SLO and OCT imaging improves the automated diagnosis and classification of multiple sclerosis.

21 Jul 2024

Weight loss reduces risky decisions and boosts mood in highly obese individuals, study finds

Researchers examine how significant weight loss in highly obese individuals influences their metabolism, psychological state, and decision-making processes.

21 Jul 2024

Early adulthood obesity linked to adverse heart outcomes in later life, study finds

A study published in the European Heart Journal reveals that fat accumulation in early or mid-adulthood adversely impacts heart structure and function in individuals aged 60-64, highlighting the importance of managing adiposity throughout life.

21 Jul 2024

UCLA chosen to lead dementia care under new Medicare alternative payment model

UCLA has been selected by the Centers for Medicare & Medicaid Services (CMS) to participate in a new Medicare alternative payment model designed to support people living with dementia and their caregivers.

19 Jul 2024

DDX41: A unique player in myeloid leukemogenesis

A new editorial paper was published in Oncotarget's Volume 15 on July 2, 2024, entitled, "DDX41 and its unique contribution to myeloid leukemogenesis."

19 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024

Fox Chase Cancer Center researchers identify new targets for mesothelioma prevention

A new research perspective was published in Oncoscience (Volume 11) on May 23, 2024, entitled, "Targeting inflammatory factors for chemoprevention and cancer interception to tackle malignant mesothelioma."

19 Jul 2024