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Corticosteroids may reduce effectiveness of immunotherapy in lung cancer

Corticosteroids, a commonly prescribed medication to alleviate cancer-related symptoms for non-small cell lung cancer patients treated with immunotherapy, are the main reason certain immunotherapies may fail in treating the disease, according to new research by Keck Medicine of USC.

7 Jul 2025

Researchers explore new therapies to prevent organ rejection without immunosuppressive drugs

While immunosuppressive medications are critical to prevent rejection of transplant organs, they also come with plenty of downsides.

7 Jul 2025

Virtual Reality therapy works very well for people with psychosis

Treatment with Virtual Reality appears to work very well for people with psychosis. It works faster than the current treatment with cognitive behavioral therapy and is at least as effective.

7 Jul 2025

Neural stem cell grafts show promise for myelin repair in multiple sclerosis

A study led by Cambridge researchers has shed light on how neural stem cell grafts could help restore myelin in the central nervous system.

7 Jul 2025

Unlocking the brain’s language to fight Alzheimer’s

June is Alzheimer's and Brain Awareness Month. With an estimated 55 million people living with Alzheimer's Disease and other forms of dementia worldwide, advancing understanding of these complex diseases is critical to finding new treatments, and potentially, cures.

7 Jul 2025

Reversing immune fatigue offers new hope for cancer treatment

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

7 Jul 2025

Growing popularity of contact sports raises concern over brain injuries in Africa

Contact sports are becoming increasingly popular in Africa, raising concern about the risk of chronic traumatic encephalopathy (CTE).

7 Jul 2025

Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunity

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor progression and dampening immune responses.

7 Jul 2025

Side of onset influences non-motor symptoms in Parkinson’s disease

Parkinson's disease often begins asymmetrically, affecting either the right or left side of the body first. Researchers from the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have demonstrated that this initial side of onset influences the progression of non-motor symptoms.

7 Jul 2025

UCLA Health researchers discover four pathways leading to Alzheimer’s disease

UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated risk factors.

7 Jul 2025

Flavonoid diversity, not just quantity, drives better health outcomes

This study reveals that diverse flavonoid intake is crucial for lowering chronic disease risk and mortality, advocating for a varied diet rich in flavonoids.

7 Jul 2025

Circadian misalignment in the blind may impact daily brain functions

This study investigates how blindness affects sleep, dreams, and spatial awareness, revealing links between circadian rhythms and cognitive performance.

7 Jul 2025

Preeclampsia in pregnancy reduces risk of some cancers but raises endometrial cancer odds

Women with preeclampsia in their first pregnancy had a lower risk of developing breast, cervical, and lung cancer later in life, but a higher risk of endometrial cancer. The large Nordic cohort study also found that siblings of women with PE had a modestly reduced risk of cancer, particularly lung cancer.

7 Jul 2025

Multifunctional nanodisk enables cancer diagnosis, treatment and immune activation

The Korea Research Institute of Standards and Science (KRISS, President Lee Ho Seong) has successfully developed a nanomaterial capable of simultaneously performing cancer diagnosis, treatment, and immune response induction.

7 Jul 2025

Early exposure to plastics raises young children’s asthma risk

A large international study found that early-life exposure to phthalates, common chemicals in plastics, is modestly associated with increased risks of asthma, wheeze, and rhinitis in children under five. No consistent associations were found for bisphenols, and effects were generally small.

6 Jul 2025

Vaping versus smoking’s impact on male fertility

A new study found that male E-cigarette users undergoing IVF had higher sperm motility and lower miscarriage rates compared to conventional smokers. However, E-cigarettes were not shown to be safe and further research is needed before recommending them for fertility.

6 Jul 2025

Study reveals hidden cause of treatment failure in acute promyelocytic leukemia

Researchers at Zhejiang University School of Medicine have identified a single point mutation in the normal PML gene that can block the effect of arsenic trioxide, a frontline drug for acute promyelocytic leukemia.

4 Jul 2025

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the associated factor EMP1 in the progression of resectable pancreatic cancer (PC).

4 Jul 2025

Fluorescent drug helps surgeons see nerves clearly during complex procedures

When surgeons dissect tissue to remove a tumor or make a repair they must work cautiously, relying on electrophysical monitors and their own anatomical knowledge to avoid cutting nerves, which could complicate the patient's recovery.

4 Jul 2025

Rare kidney cancer evades immune system in unique ways

Cancer fighting T-cells, the immune system's primary enforcers, are scarce in the rare kidney cancer called chromophobe renal cell carcinoma (ChRCC) and those that are present are indifferent to the tumor threat and traditional immune therapies, revealing the need for new targets and treatments.

4 Jul 2025