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Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131-TNF signaling pathway-mediated differentiation of immunosuppressive dendritic cells.

12 Jul 2025

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

This new article publication from Acta Pharmaceutica Sinica B, discusses how melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1.

12 Jul 2025

High-intensity focused ultrasound induces ferroptosis for tumor immune activation

This new article publication from Acta Pharmaceutica Sinica B, discusses high intensity forced ultrasound-driven ferroptosis as a strategy for anti-tumor immune priming.

12 Jul 2025

Engineered exosomal spheres enhance melanoma immunotherapy through improved tumor penetration

This new article publication from Acta Pharmaceutica Sinica B, discusses the use of engineered platelet-derived exosomal spheres for enhanced tumor penetration and extended circulation in melanoma immunotherapy.

12 Jul 2025

CMD-OPT model enables discovery of potent and selective RIPK2 inhibitor for acute liver injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how a CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury.

12 Jul 2025

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, represents a spectrum of liver disorders ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, and cirrhosis.

12 Jul 2025

Design strategies and therapeutic applications of smart materials in diabetes care

Announcing a new publication for Acta Materia Medica journal. Bioresponsive materials have gained prominence as innovative tools for advancing drug delivery systems, particularly in managing type 1 and type 2 diabetes mellitus.

12 Jul 2025

Teclistamab shows promising results in heavily pretreated multiple myeloma

Teclistamab-cqyv (Tecvayli) led to clinically meaningful responses in patients with heavily pretreated multiple myeloma who would have been ineligible for the MajesTEC-1 trial, and identified a novel factor independently associated with outcomes.

12 Jul 2025

Brain protein associated with aging not linked to youth contact sports

In recent years, some scientists and advocates have warned that playing contact sports like football and hockey may increase the risk of brain diseases like Alzheimer's disease or chronic traumatic encephalopathy (CTE) due to a buildup of a specific protein in the brain.

11 Jul 2025

New analysis reveals widespread progression of CKM syndrome across the U.S.

One in three adults in the U.S. has three or more risk factors for a newly recognized but increasingly common condition: cardiovascular-kidney-metabolic (CKM) syndrome.

11 Jul 2025

Autistic adults describe mental strain of nonverbal communication

Imagine having a conversation where every gesture and glance feels like a test. You're juggling eye contact, facial expressions, and tone of voice, all while trying to keep up with the words. You might miss something, or someone might misread you.

11 Jul 2025

More than 200 types of misfolded proteins could be associated with age-related cognitive decline

For decades, the story of Alzheimer's research has been dominated by a battle between A-beta and tau amyloids, both of which can kill neurons and impact the brain's ability to function.

11 Jul 2025

Hollywood myths about heart attacks may be putting lives at risk

Hollywood has shaped how many people imagine a heart attack-someone clutching their chest and collapsing dramatically. But those portrayals are misleading and shouldn't be expected, says Ann Eckhardt, a nursing professor and researcher at The University of Texas at Arlington.

11 Jul 2025

Genetic links between type 2 diabetes and subcortical brain structure revealed

Recently, the team led by Chief Physician Quan Zhang and Associate Professor Feng Liu at Tianjin Medical University General Hospital systematically evaluated the genetic associations between type 2 diabetes mellitus and subcortical brain structures using large-scale genome-wide association summary statistics and advanced statistical genetic methods.

11 Jul 2025

Medical Condition News

Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

High-intensity focused ultrasound induces ferroptosis for tumor immune activation

Engineered exosomal spheres enhance melanoma immunotherapy through improved tumor penetration

CMD-OPT model enables discovery of potent and selective RIPK2 inhibitor for acute liver injury

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Design strategies and therapeutic applications of smart materials in diabetes care

Teclistamab shows promising results in heavily pretreated multiple myeloma

Brain protein associated with aging not linked to youth contact sports

New analysis reveals widespread progression of CKM syndrome across the U.S.

Autistic adults describe mental strain of nonverbal communication

More than 200 types of misfolded proteins could be associated with age-related cognitive decline

Hollywood myths about heart attacks may be putting lives at risk

Genetic links between type 2 diabetes and subcortical brain structure revealed

Egr-1 gene identified as crucial regulator of regulatory T cells in multiple sclerosis

Autistic and neurotypical adults process body parts similarly in the brain

Socioeconomic gaps revealed in emergency visits for concussion among youth

Myopenia identified as key contributor to muscle loss in rheumatoid arthritis

Insecticide exposure could impair mental function in older adults

Hydrogels could be key to safer, smarter cancer drug delivery

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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