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Once-monthly obesity injection shows double-digit weight loss in major clinical trial

Researchers found that once-monthly maridebart cafraglutide led to substantial weight loss and improved glycemic control in adults with obesity, with or without diabetes, in a phase 2 randomized trial. The drug demonstrated an acceptable safety profile and supports further study in phase 3 trials.

24 Jun 2025

Unhealthy teen diets reshape the brain and drive lifelong eating habits, study finds

Adolescent diets high in fat and sugar disrupt the development of the prefrontal cortex and hippocampus, impacting cognition, memory, and impulse control. These brain changes can promote unhealthy eating behaviors and obesity risk that persist into adulthood.

24 Jun 2025

New PET/CT imaging technique enables early detection of multiple forms of cardiomyopathy

A new PET/CT imaging technique that visualizes activated fibroblasts in the heart muscle enables early detection of multiple forms of cardiomyopathy, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

24 Jun 2025

Stress-activated gene damages insulin-producing cells in type 2 diabetes

Stress does no one - not even your insulin-producing cells - any good.

24 Jun 2025

Newborns and Alzheimer's patients have elevated blood levels of phosphorylated tau

Newborn babies and patients with Alzheimer's disease share an unexpected biological trait: elevated levels of a well-known biomarker for Alzheimer's.

24 Jun 2025

Novel combination therapy targets m6A pathway to combat joint erosion in rheumatoid arthritis

A recent study published in Engineering has shed light on a novel combination therapy for rheumatoid arthritis (RA) that significantly reduces bone destruction by targeting the m6A methylation pathway.

24 Jun 2025

New KRAS mutation discovery opens door to targeted colon cancer therapies

Scientists at Fox Chase Cancer Center have identified a mutation in a common oncogene - a gene that can cause cancer - that may play an important role in colon cancer. Researchers also showed how this mutation could be targeted therapeutically.

24 Jun 2025

New AI tool characterizes the diversity of individual cells within tumors

A multinational team of researchers, co-led by the Garvan Institute of Medical Research, has developed and tested a new AI tool to better characterize the diversity of individual cells within tumors, opening doors for more targeted therapies for patients.

24 Jun 2025

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

Alcoholic liver disease exacerbates HBV reactivation and worsens outcomes in liver transplant recipients

A recent study published in Engineering has shed light on the impact of alcoholic liver disease (ALD) on post-transplant hepatitis B virus (HBV) reactivation and survival outcomes in patients with hepatocellular carcinoma (HCC).

24 Jun 2025

Study identifies potential way to slow or block progression of age-related macular degeneration

A new study from Washington University School of Medicine in St. Louis identifies a possible way to slow or block progression of age-related macular degeneration, a leading cause of blindness in people over age 50.

24 Jun 2025

CIK treatment enhances survival in early and advanced colorectal cancer

Colorectal cancer (CRC) is the second most common cause of death from cancer in the United States (US) and the most prevalent malignant tumor worldwide.

24 Jun 2025

Diabetes drug semaglutide shows promise in reducing dementia risk

Researchers at the Case Western Reserve School of Medicine have found that semaglutide, a popular diabetes and weight-loss drug, may lower the risk of dementia in people with type 2 diabetes (T2D).

24 Jun 2025

Excess trace metal levels may trigger gestational diabetes

Excess micronutrients in early pregnancy may raise gestational diabetes risks. Study links essential metal levels to GDM onset, urging a rethink on supplements.

24 Jun 2025

New genomic test predicts chemotherapy resistance in cancer patients

Chemotherapy seeks to destroy tumor cells and has been a standard treatment for cancer for decades.

24 Jun 2025

Experimental drug promotes weight loss by heating fat instead of suppressing appetite

An article published in the journal Nature Metabolism presents an experimental drug that stimulates adipose tissue cells to produce heat through a process known as thermogenesis, thereby promoting weight loss.

24 Jun 2025

Clinical trial finds new benefits of semaglutide for adults with type 1 diabetes

A new clinical trial found that taking a popular diabetes and weight-loss drug once weekly significantly improves blood sugar and leads to substantial weight loss in adults with Type 1 diabetes who use automated insulin delivery systems.

23 Jun 2025

Genetically engineered skin grafts help heal chronic wounds in patients with epidermolysis bullosa

Skin grafts genetically engineered from a patient's own cells can heal persistent wounds in people with an extremely painful dermatologic disease, a Stanford Medicine-led clinical trial has shown.

23 Jun 2025

New molecular imaging agent shows high accuracy in detecting liver cancer

A novel molecular imaging agent targeting glypican-3 (GPC3) has demonstrated high sensitivity and specificity in detecting hepatocellular carcinoma (HCC), including tumors smaller than one centimeter, according to results from a pilot clinical study.

23 Jun 2025

Capsule sponge test offers less invasive option for monitoring Barrett's esophagus

Endoscopies could be replaced by far less invasive capsule sponge tests for half of all patients with Barrett's esophagus, a known precursor to esophageal cancer, according to a new study from researchers at the University of Cambridge, Addenbrooke's Hospital and Queen Mary University of London.

23 Jun 2025

Medical Condition News

Once-monthly obesity injection shows double-digit weight loss in major clinical trial

Unhealthy teen diets reshape the brain and drive lifelong eating habits, study finds

New PET/CT imaging technique enables early detection of multiple forms of cardiomyopathy

Stress-activated gene damages insulin-producing cells in type 2 diabetes

Newborns and Alzheimer's patients have elevated blood levels of phosphorylated tau

Novel combination therapy targets m6A pathway to combat joint erosion in rheumatoid arthritis

New KRAS mutation discovery opens door to targeted colon cancer therapies

New AI tool characterizes the diversity of individual cells within tumors

Genetic markers show promise in predicting mood disorder treatment outcomes

Alcoholic liver disease exacerbates HBV reactivation and worsens outcomes in liver transplant recipients

Study identifies potential way to slow or block progression of age-related macular degeneration

CIK treatment enhances survival in early and advanced colorectal cancer

Diabetes drug semaglutide shows promise in reducing dementia risk

Excess trace metal levels may trigger gestational diabetes

New genomic test predicts chemotherapy resistance in cancer patients

Experimental drug promotes weight loss by heating fat instead of suppressing appetite

Clinical trial finds new benefits of semaglutide for adults with type 1 diabetes

Genetically engineered skin grafts help heal chronic wounds in patients with epidermolysis bullosa

New molecular imaging agent shows high accuracy in detecting liver cancer

Capsule sponge test offers less invasive option for monitoring Barrett's esophagus

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

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