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Radioprotective effects of Licochalcone B against radiation-induced cell damage

Radiation injury poses a serious threat to human health, causing complex and multifaceted damage to cells and tissues. Such injury can be caused by various factors, including nuclear accidents, medical radiation therapy, and space travel.

29 Oct 2024

Ratiometric fluorescent probes for measuring active albumin in liver disease patients

Albumin is a major prognostic factor for patients with advanced liver disease, dependent on its concentration and biological activity.

29 Oct 2024

Researchers develop new approach to predict immunotherapy response in breast cancer patients

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.

29 Oct 2024

New insights into cardiac defects in Myotonic Dystrophy Type 1

People with Myotonic Dystrophy Type 1 (DM1), the most common adult-onset form of muscular dystrophy, progressively lose muscle mass and strength in their lower legs, hands, neck and face.

29 Oct 2024

New recommendations developed to unify sJIA and AOSD

sJIA and AOSD share the same features, and the same four major symptoms. However, the two conditions have traditionally been separated by a person's age at diagnosis.

29 Oct 2024

Tiny particles deliver combined heat and chemotherapy to tumors

Patients with late-stage cancer often have to endure multiple rounds of different types of treatment, which can cause unwanted side effects and may not always help.

29 Oct 2024

Early intervention with TAVR proves safe and effective for asymptomatic aortic stenosis

The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS).

29 Oct 2024

Study highlights the need to train health professionals on gluten-free diet

According to a study by the University of the Basque Country (UPV/EHU), the Internet is the go-to source for most people with celiac disease when tackling their dietary queries.

29 Oct 2024

Patient symptom information enhances MRI accuracy for lumbar spine diagnosis

Knowing a patient's symptoms helps radiologists in lumbar spine MRI interpretation and diagnosis, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

29 Oct 2024

Study finds no benefit of routine orbital atherectomy in cardiac stenting

Routine use of an orbital atherectomy device to remove calcium from severely blocked coronary arteries before patients undergo cardiac stenting procedures does not improve outcomes, a Mount Sinai-led study has found.

29 Oct 2024

Social media analysis reveals patterns in seasonal allergies

Complaining about your allergies online might provide valuable data to researchers. Over 25% of Americans experience seasonal allergies, but how the prevalence of seasonal allergies varies across space and time remains obscure, in part because allergies seldom warrant visits to healthcare providers.

29 Oct 2024

Study aims to identify clinical subtypes in patients with schizophrenia

A research team led by Professor Takahiro Nemoto at Toho University, in collaboration with Associate Professor Naoki Hashimoto and Assistant Professor Ryo Okubo at Hokkaido University, and Dr. Satoru Ikezawa at the National Center of Neurology and Psychiatry explored the agreement or discrepancy between subjective social cognitive difficulties and actual cognitive impairment.

29 Oct 2024

One in four healthy young Marines report long-term physical, cognitive, or psychiatric effects after mild COVID-19

Researchers examine the long-term health effects of SARS-CoV-2 infection in a cohort of United States Marines.

29 Oct 2024

Urine transcriptomics: A new frontier for non-invasive genitourinary disease detection

Researchers explore the potential diagnostic utility of transcriptomic and metabolic signals in the genitourinary system.

29 Oct 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

The intersection of arts and neuroscience reveals transformative effects on health and learning, as discussed by Susan Magsamen in her neuroaesthetics research.

29 Oct 2024

Digital avatars may ease distress from troubling voices in psychosis

AVATAR-Extended therapy demonstrates effectiveness in alleviating distress from psychosis voices, promoting lasting improvements in mood and well-being.

29 Oct 2024

AI-powered avatars set for mental health trials in India and Ethiopia

AI-powered digital avatars are to be trialled for people in India and Ethiopia who hear voices in their heads, as researchers try to adapt mental health treatment so they can be used effectively in low-resource settings.

29 Oct 2024

Research uncovers intrinsic factors influencing CAR-T cell success

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion product for B-ALL patients, is highly dependent on intrinsic features of the CAR-T cells themselves and their progression within the patient.

29 Oct 2024

Innovative method promises quick cancer diagnosis using ultrathin membranes

There are billions of tiny packets of cellular material called extracellular vesicles (EVs) that are produced by cells and released into each person's blood, saliva, and other bodily fluids.

29 Oct 2024

Study uncovers six cancer susceptibility genes

Scientists at deCODE genetics/Amgen, and their collaborators have discovered six novel genes with rare germline variants that associate with cancer risk. The findings are published today in Nature Genetics under the title "Gene-based burden tests of rare germline variants identify six cancer susceptibility genes".

29 Oct 2024