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GSK3β identified as a driver of drug resistance in BRAF mutant melanoma

A new research perspective was published in Oncotarget, Volume 16, on April 4, 2025, titled "GSK3β activation is a key driver of resistance to Raf inhibition in BRAF mutant melanoma cells."

11 Apr 2025

New blood test method improves accuracy of cancer detection

A new, error-corrected method for detecting cancer from blood samples is much more sensitive and accurate than prior methods and may be useful for monitoring disease status in patients following treatment, according to a study by Weill Cornell Medicine and New York Genome Center investigators.

11 Apr 2025

Police officers at higher risk of traumatic brain injuries and PTSD

Police officers are more than twice as likely to have traumatic brain injuries compared to the general population. Officers who incur these injuries while on duty face more than double the risk of developing complex post-traumatic stress disorder (PTSD).

11 Apr 2025

More psych hospital beds are needed for kids, but neighbors say not here

In January, a teenager in suburban St. Louis informed his high school counselor that a classmate said he planned to kill himself later that day.

11 Apr 2025

GLP-1 agonists may reshape the gut microbiome

Research reveals GLP-1 receptor agonists influence gut microbiome, enhancing metabolic health and offering anti-inflammatory benefits for diabetes management.

11 Apr 2025

ChatGPT improves exercise for neurodivergent kids

A University of Michigan research team has used AI to help deliver exercise "snacks" to kids with autism.

11 Apr 2025

New guidelines released for managing hypercholesterolemia in adults over 75

The National Lipid Association (NLA) and the American Geriatrics Society (AGS) have released a Joint Scientific Statement focused on the management of hypercholesterolemia in adults older than 75 years who do not have a history of atherosclerotic cardiovascular disease (ASCVD).

10 Apr 2025

UQ's new research center aims to improve lives of people living with pain

One of the world's foremost pain experts has highlighted the risks of bypassing established processes for assessing the safety and effectiveness of medicines at the launch of a research center at the University of Queensland.

10 Apr 2025

Apathy and lack of motivation are symptoms of cancer cachexia, research suggests

Cancer ravages both body and mind. If you've ever lost loved ones to the disease, you might recognize the physical and emotional changes cancer patients often endure during their final months.

10 Apr 2025

Safety profile of centrifugation artificial liver support systems with RMA for liver failure patients

Patients with acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) are at high risk of bleeding with traditional artificial liver support systems.

10 Apr 2025

Monitoring Type 2 Diabetes progression using ultrasound localization microscopy

A research paper by scientists at The Second Affiliated Hospital of Zhejiang University School of Medicine presented the application of Ultrasound Localization Microscopy (ULM) for monitoring the progression of Type 2 Diabetes and assessing the efficacy of anti-cytokine immunotherapy.

10 Apr 2025

Surface light chain expression in B-ALL after myeloma treatment: A unique case report

Therapy-related B-lymphoblastic leukemia (B-ALL) following treatment for multiple myeloma is a rare occurrence.

10 Apr 2025

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent.

10 Apr 2025

Coaxial silicone drains reduce pain after VATS lobectomy without compromising efficacy

Chest drains are routinely used after video-assisted thoracoscopic surgery (VATS) lung resections to evacuate fluid and air from the pleural space.

10 Apr 2025

Survey reveals diverse practices in thoracic sympathetic surgery across Europe

Thoracic autonomic nervous system surgery is mainly used for hyperhidrosis/facial flushing, whereas cardiac and vascular indications are limited.

10 Apr 2025

Researchers explore drug repurposing strategy for Parkinson's disease

Despite significant advances in Parkinson's disease (PD) treatment, it remains incurable, with limited therapeutic options.

10 Apr 2025

New liver directed treatment improves outcomes for rare eye cancer

A multi-institutional study led by Moffitt Cancer Center found that percutaneous hepatic perfusion using a melphalan hepatic delivery system may help patients with a rare eye cancer that has spread to their liver.

10 Apr 2025

New data-sparse model accurately predicts individual glycemic responses

If you eat a snack - a meatball, say, or a marshmallow - how will it affect your blood sugar? It's a surprisingly tricky question: the body's glycemic response to different foods varies based on individual genetics, microbiomes, hormonal fluctuations, and more.

10 Apr 2025

Study reveals brain circuit behind apathy in advanced cancer

The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss.

10 Apr 2025

Can psychedelics break compulsive eating habits in obesity?

A review by Oxford researchers explores how psychedelics like psilocybin and LSD may help disrupt compulsive eating behaviors in subsets of obese individuals. The paper outlines proposed neurobiological, epigenetic, and gut-brain mechanisms while emphasizing the need for human trials.

10 Apr 2025