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Study identifies genetic associations with youth psychopathology

When trying to understand how genetic influences factor into youth behavior, researchers at Washington University in St. Louis have taken the "big trawl" approach, casting their net wide to pull in all the measured traits, behaviors and environments that make up who we are and examine associations with the genetic building blocks comprising risk for mental health problems.

17 Oct 2024

Edaravone shows promise in targeting brain tumor stem cells

Glioblastomas are aggressive brain tumors with a median survival time of less than 22 months despite standard therapy including surgery, irradiation, and chemotherapy.

17 Oct 2024

Study identifies biomarkers for immunotherapy success in liver cancer

It may soon be possible to determine which patients with a type of liver cancer called hepatocellular carcinoma would benefit from immunotherapy, according to a preclinical study by Weill Cornell Medicine investigators.

17 Oct 2024

Brazil-Italy joint lab focuses on Alzheimer’s drug development

A self-proclaimed Brazil-Italy collaboration enthusiast, researcher Laura Bolognesi created the B2AlzD2 Joint Lab at the Department of Pharmacy and Biotechnology of the Università di Bologna (UNIBO), the first Brazil-Bologna joint laboratory dedicated to the development of new drugs for the treatment of Alzheimer's disease.

17 Oct 2024

Boston University and GSK collaborate to tackle pulmonary fibrosis

Researchers from the Center for Regenerative Medicine (CReM) at Boston University and Boston Medical Center (BMC) have announced a new collaboration with the global biopharma company GSK to advance innovative research focused on developing cutting-edge models to study and treat lung diseases like pulmonary fibrosis.

17 Oct 2024

Innovative sensor material offers non-invasive cancer diagnosis

A research team led by Dr. Ho Sang Jung of the Advanced Bio and Healthcare Materials Research Division at the Korea Institute of Materials Science has developed an innovative sensor material that amplifies the optical signals of cancer metabolites in body fluids (saliva, mucus, urine, etc.) and analyzes them using artificial intelligence to diagnose cancer.

17 Oct 2024

New grant aims to transform treatment for liver cancer

Currently, there are a few available treatment options for liver cancer, including a combination of immunotherapies and a class of drugs known as tyrosine kinase inhibitors (TKIs), but their long-term effects are limited.

17 Oct 2024

New compounds from fungi show promise in treating colorectal cancer

Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide.

17 Oct 2024

Trial evaluates monoclonal antibodies for long COVID prevention

The first randomized, placebo-controlled clinical trial evaluating the impact of therapeutic monoclonal antibodies on the risk of developing long COVID was led by researchers at Weill Cornell Medicine.

17 Oct 2024

Medical and behavioral interventions can reduce fatigue in people with multiple sclerosis

In a study of commonly used treatments for people with multiple sclerosis, both medical and behavioral interventions, and a combination of the two, resulted in meaningful improvements in fatigue, a University of Michigan-led study finds.

17 Oct 2024

New genetic variant may predict severe ulcerative colitis in patients

Abdominal pain, diarrhea, and debilitating fatigue define the daily lives of millions of people worldwide who suffer from chronic bowel disease.

17 Oct 2024

U.S. cancer detection severely disrupted during first year of COVID-19, shows incomplete recovery in second year

A JAMA study finds COVID-19 caused a 127,931 deficit in cancer diagnoses in 2020, with recovery in 2021 influenced by demographic and community characteristics.

17 Oct 2024

Ozempic and similar drugs may lower risks for opioid and alcohol use disorders

A new study published in the scientific journal Addiction has found that people with opioid or alcohol use disorder (OUD, AUD) who take Ozempic or similar medications to treat diabetic/weight-related conditions appear to have a 40% lower rate of opioid overdose and a 50% lower rate of alcohol intoxication than people with OUD and AUD who do not take Ozempic or similar medications.

17 Oct 2024

Rising concerns over benzodiazepine prescriptions in older stroke survivors

Although there has been a slight downward trend in the prescription of benzodiazepines (depressants that relieve anxiety, muscle spasms, produce sedation and reduce seizures) among older adults over the last decade, the rate of first-time prescriptions for these medications after an ischemic (clot-caused) stroke is still sizable, according to research published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.

17 Oct 2024

GLP1R medications show promise in reducing suicidal ideation among adolescents with obesity

Adolescents treated with GLP1R drugs for obesity exhibit fewer suicidal thoughts, indicating potential mental health benefits of these medications.

17 Oct 2024

Gum disease tied to higher thrombosis risk: Could periodontal therapy help save lives?

The connection between gum disease and thrombosis underscores the role of oral health in reducing thrombotic disease risk and improving patient outcomes.

17 Oct 2024

A review of clinical features, diagnosis, and management of Mpox

A comprehensive review in JAMA outlines monkeypox's clinical presentation and management, stressing the need for increased surveillance and vaccination efforts.

17 Oct 2024

High blood pressure found to increase airway resistance and affect lung function

High blood pressure (hypertension) causes thickening of the blood vessels and hardening of the arteries (arteriosclerosis). A study conducted by Brazilian researchers has shown for the first time that a similar phenomenon occurs in the lungs. High blood pressure hardens the bronchi and increases airway resistance, impairing respiratory capacity.

17 Oct 2024

Metformin found safe for men with type 2 diabetes planning for parenthood

Potential fathers with type 2 diabetes can be reassured that taking the drug metformin is not associated with birth defects in their offspring, concludes a large study of more than 3 million pregnancies published by The BMJ today.

17 Oct 2024

Tissue chips help translate respiratory disease research into clinical applications

Scientists are developing advanced tools to understand and treat neurological symptoms such as brain fog associated with respiratory diseases like influenza.

17 Oct 2024