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Migraine is a neurological, not vascular, disorder

The latest genetic and biological research shows that migraine is a neurological, not vascular, disorder and both acute and preventive treatments being developed target peripheral and central nervous systems, according to a prominent migraine expert addressing the American Pain Society (APS)today.

18 May 2012

ACO model may improve populations-based outcomes for pain management

How will pain care be influenced by the anticipated reforms in the U.S. healthcare system? Current models of healthcare delivery offer both obstacles and opportunities for achieving quality and effectiveness in pain-related care, according to Daniel Carr, MD, Tufts University in his keynote address at the American Pain Society Annual Scientific Meeting.

18 May 2012

ArQule to present positive tivantinib Phase 2 clinical data for hepatocellular carcinoma

ArQule, Inc. and Daiichi Sankyo, Co., Ltd. today announced that an oral presentation at the Annual Meeting of the American Society of Clinical Oncology (ASCO) will feature Phase 2 trial data with tivantinib as a single agent investigational second-line treatment in hepatocellular carcinoma (HCC).

18 May 2012

Urocortin 2 improves cardiac output in Phase II study for acute decompensated heart failure

Neurocrine Biosciences, Inc. today announced efficacy and safety results from a Phase II trial of urocortin 2 in 53 patients with acute decompensated heart failure. The UNICORN study was conducted over approximately a two year period by the Cardioendocrine Research Group from the University of Otago in Christchurch, New Zealand and included patients admitted to Christchurch Hospital with acute decompensated heart failure.

18 May 2012

Pharmacyclics announces clinical abstracts on ibrutinib to be presented at ASCO annual meeting

Pharmacyclics, Inc. today announced that clinical abstracts on Bruton's Tyrosine Kinase inhibitor, ibrutinib have been selected for oral presentations at the 48th Annual Meeting of the American Society of Clinical Oncology (ASCO), June 1-5, 2012 in Chicago, IL.

18 May 2012

Health Canada approves Osiris’ Prochymal to treat acute GvHD in children

Osiris Therapeutics Inc. announced today it has received market authorization from Health Canada to market its stem cell therapy Prochymal (remestemcel-L), for the treatment of acute graft-vs-host disease (GvHD) in children.

18 May 2012

Regular eating times, extended daily fasting may prevent diabetes, obesity

It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override the adverse health effects of a high-fat diet and prevent obesity, diabetes and liver disease in mice.

18 May 2012

More than 55% of U.S. adults lose or break their sunglasses every year

More than 55 percent of adults in the United States lose or break their sunglasses every year, according to a new report by The Vision Council.

18 May 2012

Medtronic announces new results from CoreValve ADVANCE Study

Medtronic, Inc. today announced new results from the Medtronic CoreValve ADVANCE Study, which found that women and men benefitted similarly from the Medtronic CoreValve System.

From Medtronic 18 May 2012

Longer looks: Music as a means of treatment for PTSD

On one of the many days Leo Dunson wanted to die, the Iraq veteran put a gun to his temple and pulled the trigger. The loaded weapon misfired. For the troubled former soldier, it was another inexplicable failure, like his divorce or inability to make friends after returning from the war. In a Las Vegas recording studio, Dunson rapped about his life: "What's wrong with me? Got PTSD. These pills ain't working, man, I still can't think."

18 May 2012

UM School of Business Administration study aims to uncover cocaine abuse patterns

The National Institutes of Health (NIH) has granted $350,000 to a professor at the University of Miami (UM) School of Business Administration for an innovative study aimed at uncovering cocaine abuse patterns to lead to more effective treatments.

18 May 2012

MSRG researchers develop ColoREctal Wellbeing study

Researchers from the Macmillan Survivorship Research Group (MSRG), at the University of Southampton, have developed the first study of its kind looking at the experiences and needs of people after primary treatment of colorectal cancer.

18 May 2012

Effectiveness of 'quorum sensing' directly depends on density of bacterial populations

Scientists at The University of Nottingham have opened the way for more accurate research into new ways to fight dangerous bacterial infections by proving a long-held theory about how bacteria communicate with each other.

18 May 2012

ScreenCell, Affymetrix partner to distribute CTC platform

Affymetrix, Inc. and ScreenCell, a privately-held company, today announced the signing of a worldwide distribution agreement for ScreenCell's isolation devices and dilution buffers, designed for the collection of Circulating Tumor Cells (CTCs) in peripheral blood.

18 May 2012

Janssen’s NUCYNTA ER tablets more effective in providing pain management in adults with DPN

Janssen Pharmaceuticals, Inc. today announced the results of an investigational Phase 3 study suggesting NUCYNTA ER (tapentadol) extended-release tablets were significantly more effective than placebo in providing pain management among adults with chronic moderate to severe, painful diabetic peripheral neuropathy.

18 May 2012

Researchers create prosthetic retina for patients with AMD

A device which could restore sight to patients with one of the most common causes of blindness in the developed world is being developed in an international partnership.

18 May 2012

Prostate Cancer Risk Calculator offers men ‘individual risk assessment’

Men worried about prostate cancer have a new online resource, freely available, to help them assess their risk. The multi-step Prostate Cancer Risk Calculator, www.prostatecancer-riskcalculator.com*, has been created by the founders of the European Randomized Study of Screening for Prostate Cancer (ERSPC).

18 May 2012

Avraham initiates ladostigil Phase 2 trial in MCI

Avraham Pharmaceuticals Ltd. announced today the commencement of a Phase 2 clinical trial to evaluate the safety and efficacy of ladostigil in patients diagnosed with mild cognitive impairment.

18 May 2012

AACN, GE Healthcare to honor DAISY Foundation with Pioneering Spirit Award

The DAISY Foundation will receive the AACN-GE Healthcare Pioneering Spirit Award to honor its efforts to provide meaningful recognition to nurses as "unsung heroes" deserving of society's profound respect and recognition for their education, training, brainpower, skill and compassion.

18 May 2012

Dabrafenib drug shrinks tumors in patients with melanoma brain metastases

An experimental drug targeting a common mutation in melanoma successfully shrank tumors that spread to the brain in nine out of 10 patients in part of an international phase I clinical trial report in the May 18 issue of The Lancet.

18 May 2012