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ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Blocking the receptor for proteins that constrict blood vessels reduces markers of heart-related problems in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

States face Friday deadline on health exchanges

States must decide by Dec. 14 if they are going to operate their own health care marketplaces, or if they will defer to the federal government. They have until mid-February to decide whether to partner with the federal government or let the feds do it all. Meanwhile, polls in Missouri and Tennessee show public support for state-run markets.

14 Dec 2012

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumour cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal cancer, they found that genetic mutations, regarded by many as the chief suspect driving cancer growth, are only one piece of the puzzle. The team discovered that biological factors and cell behaviour - not only genes - drive tumour growth, contributing to therapy failure and relapse.

14 Dec 2012

Knocking out PKNP gene is the Achilles' heel of some cancers

Medical researchers at the University of Alberta have discovered that knocking out a particular "partner" gene is the Achilles' heel of some cancers.

14 Dec 2012

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Abnormalities of mineral metabolism worsen with progressive chronic kidney disease (CKD) and are linked with a higher risk for kidney failure among African Americans, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Cedars-Sinai scientist to study Charcot-Marie-Tooth disease

A Cedars-Sinai physician-scientist has been awarded a $3 million grant from the California Institute for Regenerative Medicine to study with new stem cell technology Charcot-Marie-Tooth disease, the most common inherited neurological disorder and which damages nerves that control muscles.

14 Dec 2012

Pairing statins with cyclin-dependent kinase inhibitors might effectively treat melanomas

A novel approach to identifying potential anticancer drug combinations revealed that pairing cholesterol-reducing drugs called statins with cyclin-dependent kinase inhibitors might provide an effective approach to treating intractable melanomas driven by mutations in the NRAS and KRAS gene.

14 Dec 2012

Lyncean Technologies announces first sale of Compact Light Source

Palo Alto-based Lyncean Technologies, Inc., today announced its first sale of a Compact Light Source, a miniature synchrotron X-ray source employing state-of-the-art laser-beam and electron-beam technology.

14 Dec 2012

Study examines Medicare out-of-pocket expenses in the last 5 years of life

Should your 82-year-old dad, who has been declining after a stroke, get hip surgery after a fall? Would your 43-year-old sister, fighting late-stage cancer, benefit from an experimental drug that could have serious side effects? These are wrenching decisions.

14 Dec 2012

New technique may allow more kidney cancer patients to avoid conventional open surgery

Urologists at Henry Ford Hospital have developed a new technique that could make minimally invasive robotic partial nephrectomy procedures the norm, rather than the exception for kidney cancer patients. The technique spares the kidney, eliminates long hospital stays and provides better outcomes by giving the surgeon more time to perform the procedure.

14 Dec 2012

SLU researchers to study physiological and biochemical functions in lupus

Two researchers at Saint Louis University's division of rheumatology in the department of internal medicine have been awarded a $1.8 million NIH grant to study the physiological and biochemical functions in lupus, an autoimmune disease, and develop possible new medications for its treatment.

14 Dec 2012

AMSSM statement on ‘Concussion in Sport’

The American Medical Society for Sports Medicine releases its latest position statement, "Concussion in Sport," which recommends healthcare professionals apply a more individualized approach in the diagnosis and care management of sports concussion, a traumatic head injury with a reported 3.8 million occurrences per year.

14 Dec 2012

At-home exercise regimen sufficient to increase cancer patients' mobility and reduce fatigue

It has been known for some time that exercise is important for cancer patients, but few studies have looked at the practicality of exercise programs and whether even a minimal workout can help.

14 Dec 2012

Swift Charities donates $15,262 to Waylon Jennings Fund for Diabetes Research at TGen

Swift Charities, the charitable arm of Swift Transportation, today donated $15,262 to The Waylon Jennings Fund for Diabetes Research at the Translational Genomics Research Institute (TGen).

14 Dec 2012

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Scientists have identified a new mutation in the gene that causes the inherited disease known as Alpha-1 Antitrypsin Deficiency (Alpha-1), which affects roughly one in 2,500 people of European descent.

14 Dec 2012

Computer simulation can predict risk of irregular heart rhythms and sudden cardiac death

A computer model of the heart wall predicted risk of irregular heart rhythms and sudden cardiac death in patients, paving the way for the use of more complex cardiac models to calculate the consequences of genetic, lifestyle and other changes to the heart.

14 Dec 2012

Researchers discover two-faced group of cells at work in human colon cancer

Northwestern Medicine researchers have discovered a "two-faced" group of cells at work in human colon cancer, with opposing functions that can suppress or promote tumor growth. These cells are a subset of T-regulatory (Treg) cells, known to suppress immune responses in healthy individuals.

14 Dec 2012

Scientists discover FAIM molecule as potential biomarker for bone marrow cancer

Singapore scientists have identified FAIM, a molecule that typically prevents cell death, as a potential biomarker to identify an incurable form of cancer in the bone marrow.

14 Dec 2012

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs.

14 Dec 2012

New evidence about benefits of marriage

There's new evidence about the benefits of marriage. Women who are married suffer less partner abuse, substance abuse or post-partum depression around the time of pregnancy than women who are cohabitating or do not have a partner, a new study has found.

14 Dec 2012

Medical Condition News

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

States face Friday deadline on health exchanges

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Knocking out PKNP gene is the Achilles' heel of some cancers

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Cedars-Sinai scientist to study Charcot-Marie-Tooth disease

Pairing statins with cyclin-dependent kinase inhibitors might effectively treat melanomas

Lyncean Technologies announces first sale of Compact Light Source

Study examines Medicare out-of-pocket expenses in the last 5 years of life

New technique may allow more kidney cancer patients to avoid conventional open surgery

SLU researchers to study physiological and biochemical functions in lupus

AMSSM statement on ‘Concussion in Sport’

At-home exercise regimen sufficient to increase cancer patients' mobility and reduce fatigue

Swift Charities donates $15,262 to Waylon Jennings Fund for Diabetes Research at TGen

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Computer simulation can predict risk of irregular heart rhythms and sudden cardiac death

Researchers discover two-faced group of cells at work in human colon cancer

Scientists discover FAIM molecule as potential biomarker for bone marrow cancer

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

New evidence about benefits of marriage

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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