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Lilly, Boehringer Ingelheim announce results from linagliptin Phase III trial on T2D

Boehringer Ingelheim and Eli Lilly and Company presented results from a randomised Phase III clinical trial and a post-hoc analysis for linagliptin at ADA.

11 Jun 2012

Florida Hospital, Profil Institute to establish new center for metabolic disease research

Profil Institute for Clinical Research, Inc., a company focused on early phase clinical trials for diabetes and obesity, and Florida Hospital, one of nation's largest clinical care providers, announced today a joint venture to establish a state-of-the-art early phase clinical services center for metabolic disease research, including diabetes, obesity and cardiometabolic diseases.

11 Jun 2012

Majority of African-American patients with hypertension suffer from hidden heart disease

A Wayne State University School of Medicine study has found that an overwhelming majority of African-American patients with hypertension also suffered hidden heart disease caused by high blood pressure even though they displayed no symptoms.

11 Jun 2012

Study confirms linear association between JBA and future stroke rate

Researchers from the Imperial College Faculty of Medicine in London in the United Kingdom revealed that the presence and size of a juxtaluminal black (hypoechoic) area (JBA) on carotid ultrasound of asymptomatic carotid artery plaques can predict the occurrence of ipsilateral ischemic stroke.

11 Jun 2012

Incyte, Lilly announce 12-week results from baricitinib Phase IIb study on RA

Eli Lilly and Company and Incyte Corporation announced the presentation of 12-week results from a Phase IIb study of baricitinib, formerly LY3009104 (INCB28050), an orally available janus kinase (JAK) inhibitor, in patients with active rheumatoid arthritis.

11 Jun 2012

ADAM28 inhibits VWF-mediated cancer cell apoptosis and enhances lung metastases

ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives a substantial reduction in lung metastases, according to a study published June 8 in the Journal of The National Cancer Institute.

11 Jun 2012

CLC bio implements specialized antibody engineering and selection module for Crucell

Today CLC bio announced the completion and final implementation of a specialized antibody engineering and selection module for Crucell, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, that integrates with CLC bio's bioinformatics platform.

11 Jun 2012

Lexicon presents six posters on LX4211 at ADA meeting

Lexicon Pharmaceuticals, Inc. will present six posters summarizing the mechanism of action and safety of LX4211, a dual inhibitor of sodium glucose transporters 1 and 2 (SGLT1 and SGLT2) currently in mid-stage development for type 2 diabetes, at the 72nd Scientific Sessions of the American Diabetes Association (ADA) in Philadelphia, Pennsylvania during the Saturday morning poster session on June 9, 2012.

10 Jun 2012

Vitamin D deficiency may account for unexplained disparities in cancer survival rates

A paper just published in Dermato-Endocrinology suggests that vitamin D deficiency may account for unexplained disparities in cancer survival rates between African and White Americans.

10 Jun 2012

Piramal to present data on several molecular imaging compounds at SNM annual meeting

Piramal Imaging SA, a subsidiary of Piramal Healthcare Limited, will present data on several compounds from its molecular imaging portfolio at the Society of Nuclear Medicine's 59th annual meeting in Miami Beach, Fla., from June 9 - 13.

10 Jun 2012

Researchers describe germ line functions of par-5 gene

Certain proteins, such as 14-3-3, conserve their basic functions of cell cycle control in diverse organisms, from worms to humans. In a study led by Juli-n Cer-n and Sim- Schwartz Jr, researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Research Institute of Vall d'Hebron (VHIR) respectively, have described germ line functions of par-5, which is one of the two 14-3-3 proteins existing in Caenorhabditis elegans, worms used as experimental model in genetic studies.

10 Jun 2012

UF Proton Therapy Institute successfully treats first eye cancer patient

The fixed beam room, or eyeline, at the University of Florida Proton Therapy Institute is up and running and radiation oncologist Robert Malyapa, M.D., Ph.D. completed treating the facility's first eye cancer patient this week.

10 Jun 2012

JCAD publishes results from clincal study of Tria Skin Perfecting Blue Light for acne

The Journal of Clinical and Aesthetic Dermatology (JCAD), a respected peer-reviewed dermatology publication, has, in its May 2012 issue, published the results of a single-center study of the Tria Skin Perfecting Blue Light for acne, showcasing the overall effectiveness of the device in significantly reducing the amount of acne, as well as the frequency, severity and redness of acne flares.

10 Jun 2012

Mechanochemical ablation catheter as effective as current endothermal techniques

In its first human trial, the mechanochemical ablation (MOCA) catheter was efficacious at two years as current endothermal techniques, but without the need of tumescent anesthesia. In addition, MOCA was more effective than results of foam sclerotherapy of the great saphenous vein (GSV) and is another alternative modality for most incompetent GSV's and small saphenous veins.

10 Jun 2012

Effective ways of detecting onset of kidney disease

Research led by an Arizona State University biomedical engineer and physicist to find more effective ways of detecting the onset of kidney disease is getting support from the National Institutes of Health.

8 Jun 2012

CSL Behring rIX-FP granted Orphan Drug Designation to treat hemophilia B

CSL Behring announced today that the company has been granted Orphan Drug Designation by the United States Food and Drug Administration for its novel recombinant fusion protein linking coagulation factor IX with recombinant albumin (rIX-FP).

8 Jun 2012

Directly taking accident victims to a trauma centre increases chances of survival

People who are seriously injured in a car accident are more than 30 per cent more likely to survive at least 48 hours if they are taken directly to a trauma centre than those who are taken first to a non-trauma centre, new research has found.

8 Jun 2012

High radon levels in Extremadura

Researchers at the University of Extremadura have measured levels of the radioactive gas radon in 130 workplaces in the Spanish region of Extremadura. The results revealed that 13% of shops, schools, offices, museums and other buildings exceeded EU recommended levels. The record for the highest level of radon is held by a cave in the north of Cáceres in Western Spain.

8 Jun 2012

VisionCare expands CentraSight telescope implant provider teams

VisionCare Ophthalmic Technologies, Inc., developer of the first FDA-approved ophthalmic telescope implant indicated to improve vision in patients with end-stage age-related macular degeneration (AMD), announced today the expansion of its CentraSight™ provider teams nationwide.

8 Jun 2012

Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD

Amgen today announced top-line results of the Phase 3 EVOLVE (EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events) trial, which evaluated Sensipar/Mimpara (cinacalcet) for the reduction of the risk of mortality and cardiovascular (CV) events among 3,883 patients with secondary hyperparathyroidism (HPT) and chronic kidney disease (CKD) receiving dialysis.

8 Jun 2012

Medical Condition News

Lilly, Boehringer Ingelheim announce results from linagliptin Phase III trial on T2D

Florida Hospital, Profil Institute to establish new center for metabolic disease research

Majority of African-American patients with hypertension suffer from hidden heart disease

Study confirms linear association between JBA and future stroke rate

Incyte, Lilly announce 12-week results from baricitinib Phase IIb study on RA

ADAM28 inhibits VWF-mediated cancer cell apoptosis and enhances lung metastases

CLC bio implements specialized antibody engineering and selection module for Crucell

Lexicon presents six posters on LX4211 at ADA meeting

Vitamin D deficiency may account for unexplained disparities in cancer survival rates

Piramal to present data on several molecular imaging compounds at SNM annual meeting

Researchers describe germ line functions of par-5 gene

UF Proton Therapy Institute successfully treats first eye cancer patient

JCAD publishes results from clincal study of Tria Skin Perfecting Blue Light for acne

Mechanochemical ablation catheter as effective as current endothermal techniques

Effective ways of detecting onset of kidney disease

CSL Behring rIX-FP granted Orphan Drug Designation to treat hemophilia B

Directly taking accident victims to a trauma centre increases chances of survival

High radon levels in Extremadura

VisionCare expands CentraSight telescope implant provider teams

Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD

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