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Checklist for seniors to reduce risk of falls

For those 65 and older, falling can be fatal; in fact, the Centers for Disease Control and Prevention (CDC) reports that falls are the leading cause of injury-related deaths among this age group, and some 40 percent of seniors fall at least once each year. Additionally, one in four who sustains a hip fracture from a fall will die within a year, and another 50 percent will never return to their pre-fall level of mobility.

27 Apr 2012

Gas NO plays a fundamental regulatory role in controlling bacterial function

Bacteria provide a well-known playground for scientists and the evolution of these earliest life forms has shed important perspective on potential therapies for some of the most common, deadly diseases. Researchers at Case Western Reserve University School of Medicine have now discovered that, the gas nitric oxide (NO), produced in all cells of the human body for natural purposes, plays a fundamental regulatory role in controlling bacterial function, via a signaling mechanism called S-nitrosylation (SNO), which binds NO to protein molecules.

27 Apr 2012

Researchers discover small molecules that kill HPV-infected cancer cells

Researchers at The Wistar Institute announce the discovery of small molecules that kill cancer cells caused by infection with human papillomavirus (HPV). Their results, in both cell and mouse models, demonstrate that the small molecule inhibitors protect a tumor-suppressing protein targeted by viral proteins, thus killing the infected tumor cells.

27 Apr 2012

Kras gene triggers metabolic changes that fuel cancer cells

Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.

27 Apr 2012

Home-based dialysis more popular in developing countries

Researchers at Lawson Health Research Institute have discovered that developing countries have faster growing rates of use of home-based dialysis (called peritoneal dialysis) for kidney failure than the developed world. Despite home-based dialysis' reduced cost and better outcomes, developed countries (including Canada) are using this form of therapy less.

27 Apr 2012

Study explores resilin-like materials for vocal fold disorders

A one-inch long grasshopper can leap a distance of about 20 inches. Cicadas can produce sound at about the same frequency as radio waves. Fleas measuring only millimeters can jump an astonishing 100 times their height in microseconds. How do they do it? They make use of a naturally occurring protein called resilin.

27 Apr 2012

Rochester researcher to continue MS study

A Rochester, New York, researcher will receive a $263,622 grant to continue his study of injury to brain cell connections (synapses) in multiple sclerosis (MS) through the American Brain Foundation (formerly the American Academy of Neurology Foundation) and the National Multiple Sclerosis Society Clinician-Scientist Development Award.

27 Apr 2012

Hemodiafiltration does not improve kidney failure patients' survival or heart health

A technique that removes additional toxins during dialysis does not improve kidney failure patients' survival or heart health, but intense treatments may provide a benefit, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

27 Apr 2012

Conference to focus on deep brain stimulation for OCD, depression

Deep brain stimulation, increasingly recognized as an effective therapy for certain cases of Parkinson's disease, dystonia and tremor, also may help patients who suffer from obsessive-compulsive disorder or depression that fails to respond to other treatments.

27 Apr 2012

Combination of Velcade and Fasudil could treat NSCLC

A common cancer drug and a drug used for a rare condition affecting the heart could together treat an aggressive form of lung cancer called non-small cell lung cancer (NSCLC), according to a study published in Cell today.

27 Apr 2012

Accuray launches Prostate Advances in Comparative Evidence Study

Accuray Incorporated, the premier radiation oncology company, announced today the launch of the Prostate Advances in Comparative Evidence (PACE) Study, an international, multi-center, randomized study to compare CyberKnife® Stereotactic Body Radiation Therapy (SBRT), da Vinci assisted and manual laparoscopic surgery and conventionally fractionated intensity modulated radiation therapy (IMRT), for the treatment of localized prostate cancer.

27 Apr 2012

First study to show SCAT2 as useful sideline tool for concussion

Princeton's Margot Putukian, MD presented "Prospective Clinical Assessment (SCAT2), Hybrid Neuropsychological Testing and Neuroimaging in the Evaluation of Sports-Related Concussions" at the 21st American Medical Society for Sports Medicine Annual Meeting in Atlanta, Ga. on April 24, 2012.

27 Apr 2012

FDA ODAC to review Onyx’s NDA for carfilzomib

Onyx Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee (ODAC) will review the company's new drug application (NDA) for carfilzomib for the treatment of patients with relapsed and refractory multiple myeloma who have received at least two prior therapies. ODAC will review carfilzomib at its meeting on June 20, 2012.

27 Apr 2012

City centre residents more likely to suffer from coronary artery calcification

City centre residents who took part in a study were almost twice as likely to suffer from coronary artery calcification (CAC), which can lead to heart disease, than people who lived in less polluted urban and rural areas, according to research published in the May issue of the Journal of Internal Medicine.

27 Apr 2012

Heart can regulate energy balance throughout the body

UT Southwestern Medical Center researchers have demonstrated for the first time that the heart can regulate energy balance throughout the body, a finding that may point to more effective treatments for obesity, diabetes, and heart disease.

27 Apr 2012

New X-ray technique can identify tissue fibers in the heart

Scientists at the University of Liverpool have developed a new X-ray technique to identify tissue fibres in the heart that ensure the muscle beats in a regular rhythm.

27 Apr 2012

Aspirin can reduce chance of dying from bowel cancer by 30%

Taking aspirin after being diagnosed with bowel cancer can reduce the chance of dying from the disease by 30 per cent, new research shows today.

27 Apr 2012

HMS researcher receives $130,000 to conduct epilepsy study

A researcher from Beth Israel Deaconess Medical Center and Harvard Medical School is receiving $130,000 to conduct further research on memory dysfunction in epilepsy patients through the Susan S. Spencer Clinical Research Training Fellowship.

27 Apr 2012

Irreversible Electroporation can more effectively kill cancer cells with BNNTs

A new study has shown that adding boron-nitride nanotubes to the surface of cancer cells can double the effectiveness of Irreversible Electroporation, a minimally invasive treatment for soft tissue tumors in the liver, lung, prostate, head and neck, kidney and pancreas.

27 Apr 2012

Researchers discover how adult brain can adapt to new situations

They say you can't teach an old dog new tricks. Fortunately, this is not always true. Researchers at the Netherlands Institute for Neuroscience have now discovered how the adult brain can adapt to new situations. The Dutch researchers' findings are published on Wednesday in the prestigious journal Neuron. Their study may be significant in the treatment of neurodevelopmental disorders such as epilepsy, autism and schizophrenia.

27 Apr 2012