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USPTO issues two Notices of Allowance to AcelRx for NanoTab formulations

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain, today announced that the U.S. Patent and Trademark Office (USPTO) has issued AcelRx two Notices of Allowance for the patent applications entitled "Small-Volume Oral Transmucosal Dosage Forms" and "Bioadhesive Drug Formulations for Oral Transmucosal Delivery."

12 Apr 2012

Education tool helps chest pain patients decide on stress testing

Chest pain patients educated about their future heart attack risk and involved in deciding care options were more likely than less-aware patients to opt out of stress testing, according to research in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

12 Apr 2012

Scientists aim to develop new testing methods for drug-induced liver failure

Liver damage caused by medicinal drugs is one of the most common reasons for liver failure and liver transplants in the Western world. Nevertheless, it is difficult to predict which active ingredients will turn out to be toxic for the organ. Oftentimes the problems are not discovered until the drug is already on the market. Prof. Dr. Jens Timmer, Freiburg physicist and Director of the FRIAS School of Life Sciences - LifeNet, is a project partner in a consortium that wants to solve this problem.

12 Apr 2012

People with PNES do not necessarily experience more frequent or severe stressful events

Based on their clinical experience and observations, a team of Johns Hopkins physicians and psychologists say that more than one-third of the patients admitted to The Johns Hopkins Hospital's inpatient epilepsy monitoring unit for treatment of intractable seizures have been discovered to have stress-triggered symptoms rather than a true seizure disorder.

12 Apr 2012

Four abstracts on spatial neglect to be presented at upcoming AAN meeting

Anna M. Barrett, MD will represent Kessler Foundation's Stroke Rehabilitation Research Laboratory at the upcoming American Academy of Neurology Conference at the Ernest N. Morial Convention Center in New Orleans, LA, April 21 - April 28.

12 Apr 2012

U.S. spends more on cancer care, but gains time in return

A new analysis published in Health Affairs found that American cancer patients lived almost two years longer than those in 10 European countries -- leading the researchers to say that the additional expense is worth it.

12 Apr 2012

ECG abnormalities associated with increased risk of CHD in older adults

In a study that included elderly men and women without preexisting cardiovascular disease, major and minor electrocardiographic abnormalities were associated with an increased risk of coronary heart disease (CHD) events and improved the prediction of CHD events such as heart attack, beyond traditional cardiovascular risk factors, according to a study in the April 11 issue of JAMA.

12 Apr 2012

TBI can negatively affect medical decision-making capacity

A traumatic brain injury can negatively affect a patient's medical decision-making ability at a time when patients or their families must make myriad complex decisions, say researchers from the University of Alabama at Birmingham.

12 Apr 2012

Preliminary results from GE Healthcare’s flutemetamol Phase 3 studies on AD

GE Healthcare today announced the preliminary results of two Phase 3 studies of its investigational PET amyloid imaging agent, [18F]flutemetamol, where both studies met their primary endpoints. One study, in terminally ill patients who agreed to undergo brain autopsy, showed strong concordance between flutemetamol PET images and Alzheimer's disease-associated beta amyloid brain pathology.

12 Apr 2012

Study: Stem cells from pelvic bone marrow may help hearts beat stronger

Stem cells from the pelvic bone may help hearts beat stronger. Doctors and other clinicians at the Orlando Health Heart Institute are researching the use of stem cells from pelvic bone marrow to restore tissue and improve heart function after muscle damage from heart attacks.

12 Apr 2012

Biogen Idec launches FAMPYRA in Canada

Today, Biogen Idec Canada announces that FAMPYRA (fampridine sustained release tablets or fampridine SR) is now available for prescription for patients living with multiple sclerosis (MS) in Canada.

12 Apr 2012

ST2 more specific than BNP for heart failure diagnosis

Critical Diagnostics today announced publication in the latest issue of the Journal of Heart Failure results of a study involving 995 patients who presented to the emergency room (ER) with chest pain. The study concluded that in this undifferentiated, symptomatic patient population ST2 was more specific for acute heart failure than BNP and that ST2 is independently predictive of future death and/or heart failure and has incremental utility in combination with BNP.

12 Apr 2012

Transcription factors do not act like an 'on-off' switch

A UNC-led team of scientists has now shown that transcription factors don't act like an 'on-off' switch, but instead can exhibit much more complex binding behavior.

12 Apr 2012

Mayo Clinic to offer novel device for patients with GERD

Mayo Clinic in Florida will be one of the first health care institutions in the United States to offer a newly approved device to treat gastroesophageal reflux disease (GERD). The condition, also known as acid reflux disease, can lead to serious health problems.

12 Apr 2012

Researchers discover a lead on the origin of chronic lymphatic leukaemia

Up until now the causes of the development of chronic lymphatic leukaemia, the most common form of cancer of the blood in Europe, have been unknown. At present a cure is not possible. A research group at the MedUni Vienna led by Christoph Steininger of the University Department of Internal Medicine I has now however discovered a lead on the origin of this disease. Says Steiniger: "This could influence the therapy approach taken in treating chronic lymphatic leukaemia."

12 Apr 2012

Boston Scientific launches Z Flex-270 Steerable Sheath in the U.S.

Boston Scientific Corporation announces the U.S. market launch of its Z Flex-270 Steerable Sheath. The device is intended for use in a wide range of electrophysiology (EP) procedures to facilitate the introduction and placement of diagnostic and therapeutic catheters within the heart.

12 Apr 2012

MacuCLEAR to initiate MC-1101 Phase III studies on early-stage AMD

MacuCLEAR, Inc., a clinical stage specialty pharmaceutical company focused on discovering and developing novel solutions for vascular disorders of the eye, announced today it is beginning Phase III studies for its lead compound, MC-1101, for early-stage (Dry) age-related macular degeneration (AMD), based on positive feedback during the company's end-of-Phase II meeting with the FDA.

12 Apr 2012

Lung cancer screening could be cost effective: Study finds

A new study shows that screening longtime tobacco users for lung cancer would be less costly than the widely accepted practice of screening for breast, cervical and colorectal cancers and would reduce the death toll of lung cancer by an estimated 15,000 lives a year.

11 Apr 2012

Dementia burden on the Australian economy raises concerns

The report by the World Health Organization and Alzheimer's Disease International added that policy priorities should include raising awareness of the disease ensuring timely diagnosis. It estimates the global cost of dementia is more than $600 billion per year.

11 Apr 2012

Computer modeling supports theory that many dementias spread like prion diseases

A new technique for analyzing brain images offers the possibility of using magnetic resonance imaging (MRI) to predict the rate of progression and physical path of many degenerative brain diseases, report scientists at the San Francisco VA Medical Center and the University of California, San Francisco.

11 Apr 2012