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Novel drug combination for patients with NRAS-mutant melanoma

A new study published online in Nature Medicine, led by scientists at The University of Texas MD Anderson Cancer Center, describes the discovery of a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options.

17 Sep 2012

Jennerex Phase 2 JX-594 clinical data for hepatocellular carcinoma presented at ILCA meeting

Jennerex, Inc., a private, clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic immunotherapies, presented Phase 2 clinical data of JX-594 delivered first intravenously and subsequently through intra-tumoral route demonstrating safety as well as disease control and tumor responses in patients with hepatocellular carcinoma (liver cancer, HCC).

17 Sep 2012

Risks of antidiabetic drug substantially overrated for patients with reduced kidney function

The antidiabetic drug metformin is not prescribed for patients with reduced kidney function because the risk of adverse effects has been regarded as unacceptably high. A study at Sahlgrenska Academy, University of Gothenburg, Sweden, has found that the risks have been substantially overrated. As a result, many more patients with diabetes may be able to enjoy the benefits of the medication.

17 Sep 2012

Bed nets and insecticides could fail to protect people from new malaria-transmitting mosquitoes

A potentially dangerous new malaria-transmitting mosquito has been discovered in Kenya by scientists from the London School of Hygiene & Tropical Medicine. This species, which has never been implicated in the transmission of malaria before, poses a threat because it bites humans at times when they are not protected by current malaria control techniques.

17 Sep 2012

Drug-resistant tuberculosis: an interview with Sven Hoffner

In contrast to drug-susceptible tuberculosis, which can be cured with available drug therapies, drug-resistant, and especially multi-drug resistant, tuberculosis is much more difficult to cure and it takes a much longer time for patients to become non-infectious.

17 Sep 2012

Progenra’s P5091 inhibits growth of bortezomib resistant multiple myeloma tumor cells

Researchers at the Dana-Farber Cancer Institute and Progenra, Inc. announce the publication of a research article entitled "A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance."

17 Sep 2012

Breath testing could discriminate between benign and malignant pulmonary nodules

A pilot study, published in the October 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed that breath testing could be used to discriminate between benign and malignant pulmonary nodules.

17 Sep 2012

Results from largest ever health and lifestyle survey of cities and conurbations across Europe

Researchers have announced the results of the largest ever health and lifestyle survey of cities and conurbations across Europe - including five British urban centres.

From The University of Manchester 17 Sep 2012

MVK mutations linked to disseminated superficial actinic porokeratosis

A Chinese research team, led by Anhui Medical University and BGI, has found the strong genetic evidences of mevalonate kinase gene (MVK) mutations link to disseminated superficial actinic porokeratosis (DSAP).

17 Sep 2012

Fifth Military Vision Research Symposium to take place from Sept. 18-20

Eye injuries in war have changed - and increased in number - as weapons, tactics, technology and strategies have evolved. Today's soldiers face threats from explosive devices that cause extensive damage areas not protected by body armor. Military experts and ophthalmologists from the Schepens Eye Research Institute, Massachusetts Eye and Ear will convene in Boston, Mass., on Sept. 18 to address these issues at the Fifth Military Vision Research Symposium.

15 Sep 2012

Cardiovascular mortality in Brazil has increased 3.5 times more than in other developing countries

Despite Brazil's successful prevention campaigns which have contributed to a reduction in risk factors such as smoking, cardiovascular disease (CVD) remains the first cause of death in the country, at 32%. Tobacco consumption and decrease of salt in local diets are some of the risk factors that will be discussed at the 67th Annual Congress of the Brazilian Society of Cardiology which takes place in Recife, Brazil from 14 to 17 September 2012.

15 Sep 2012

Scientists describe how natural selection occurs at the cellular level

Scientists from the Spanish National Cancer Research Centre (CNIO) describe how natural selection also occurs at the cellular level, and how our body's tissues and organs strive to retain the best cells in their ranks in order to fend off disease processes.

15 Sep 2012

Alzheimer's pathology might be increased in patients after surgery and anesthesia

A syndrome called "post-operative cognitive decline" has been coined to refer to the commonly reported loss of cognitive abilities, usually in older adults, in the days to weeks after surgery. In fact, some patients time the onset of their Alzheimer's disease symptoms from a surgical procedure.

15 Sep 2012

Biocompatibles, Philips to develop new treatment protocol for trans-arterial embolization

Royal Philips Electronics and Biocompatibles, a BTG international group company, announced a collaboration to advance the use of image guidance to control the delivery of beads during the arterial embolization of hypervascularized tumors today at the annual CIRSE (Cardiovascular and Interventional Radiological Society of Europe) meeting.

15 Sep 2012

MIT engineers use ultrasound waves to enhance permeability of skin to drugs

Using ultrasound waves, MIT engineers have found a way to enhance the permeability of skin to drugs, making transdermal drug delivery more efficient. This technology could pave the way for noninvasive drug delivery or needle-free vaccinations, according to the researchers.

15 Sep 2012

Treatment access is essential component of fight against NCDs

"The non-communicable disease [NCD] community always talks about the importance of prevention; many consider it the Holy Grail in the fight against NCDs. Why was it so hard to also accept treatment as part of the solution?" Princess Dina Mired, director general of the King Hussein Cancer Foundation in Amman, Jordan, asks in the Huffington Post "Impact" blog, noting only one target of the 2011 U.N. High-Level Meeting on NCDs "deals with treatment, the target on 'essential medicines and basic technologies for treatment.'"

15 Sep 2012

New stem cell differentiation study could help scientists better understand genetic basis of CVD

The fate of an embryonic stem cell, which has the potential to become any type of body cell, is determined by a complex interaction of genes, proteins that bind DNA, and molecules that modify those genes and proteins.

15 Sep 2012

Wake Forest Baptist to identify genetic variants associated with premature cardiovascular disease

Researchers at Wake Forest Baptist Medical Center are leading a four-year, $8.9 million national project to identify variations in the human genome and corresponding changes in the arterial proteins associated with premature development of atherosclerosis.

15 Sep 2012

Brandeis University biology professor receives NIH Director's New Innovator award

Chances are you didn't spend much time this morning getting your shoes on or thinking about which route you would take to work. But for people suffering with debilitating diseases such as ALS (Lou Gehrig's disease) or Alzheimer's, such simple functions -- and even activities like breathing and eating -- can be a struggle.

15 Sep 2012

New York City Board of Health Oks nation's first ban of oversized sugary drinks

The mayoral-appointed panel outlawed the sale of sugary drinks in sizes larger than 16 ounces nearly everywhere, except in grocery and convenience stores.

15 Sep 2012

Medical Condition News

Novel drug combination for patients with NRAS-mutant melanoma

Jennerex Phase 2 JX-594 clinical data for hepatocellular carcinoma presented at ILCA meeting

Risks of antidiabetic drug substantially overrated for patients with reduced kidney function

Bed nets and insecticides could fail to protect people from new malaria-transmitting mosquitoes

Drug-resistant tuberculosis: an interview with Sven Hoffner

Progenra’s P5091 inhibits growth of bortezomib resistant multiple myeloma tumor cells

Breath testing could discriminate between benign and malignant pulmonary nodules

Results from largest ever health and lifestyle survey of cities and conurbations across Europe

MVK mutations linked to disseminated superficial actinic porokeratosis

Fifth Military Vision Research Symposium to take place from Sept. 18-20

Cardiovascular mortality in Brazil has increased 3.5 times more than in other developing countries

Scientists describe how natural selection occurs at the cellular level

Alzheimer's pathology might be increased in patients after surgery and anesthesia

Biocompatibles, Philips to develop new treatment protocol for trans-arterial embolization

MIT engineers use ultrasound waves to enhance permeability of skin to drugs

Treatment access is essential component of fight against NCDs

New stem cell differentiation study could help scientists better understand genetic basis of CVD

Wake Forest Baptist to identify genetic variants associated with premature cardiovascular disease

Brandeis University biology professor receives NIH Director's New Innovator award

New York City Board of Health Oks nation's first ban of oversized sugary drinks

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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