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Researchers show how errant form of LYP can disrupt the immune system

Autoimmune diseases, such as Type I diabetes and rheumatoid arthritis, are caused by an immune system gone haywire, where the body's defense system assaults and destroys healthy tissues. A mutant form of a protein called LYP has been implicated in multiple autoimmune diseases, but the precise molecular pathway involved has been unknown.

19 Mar 2012

Addition of two MRI sequences to MRPA improves detection of pulmonary embolism

New research shows that the addition of two magnetic resonance imaging (MRI) sequences to a common MR angiography technique significantly improves detection of pulmonary embolism, a potentially life-threatening condition traditionally diagnosed through computed tomography.

19 Mar 2012

East Asian BIM gene variant contributes to drug resistance in cancer

A multi-national research team led by scientists at Duke-NUS Graduate Medical School has identified the reason why some patients fail to respond to some of the most successful cancer drugs.

19 Mar 2012

Study reveals how Bdnf gene mutation contributes to severe obesity

Researchers at Georgetown University Medical Center have revealed how a mutation in a single gene is responsible for the inability of neurons to effectively pass along appetite suppressing signals from the body to the right place in the brain. What results is obesity caused by a voracious appetite.

19 Mar 2012

Klf4 protein an important regulator of inflammation: HNK study

Microglia are the first line defence of the brain and are constantly looking for infections to fight off. Overactive microglia can cause uncontrolled inflammation within the brain, which can in turn lead to neuronal damage. New research published in BioMed Central's open access journal Journal of Neuroinflammation shows that, honokiol (HNK) is able to down-regulate the production of pro-inflammatory cytokines and inflammatory enzymes in activated microglia via Klf4, a protein known to regulate DNA.

19 Mar 2012

Scientist generates mutant version of IL-2 protein to treat advanced cancers

The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist has generated a mutant version of the protein whose modified shape renders it substantially more potent than the natural protein while reducing its toxicity.

19 Mar 2012

Westmead Hospital endorse a new medical device designed to increase blood circulation and prevent Deep Vein Thrombosis

A new medical device, the geko™, designed to increase blood circulation through neuromuscular electro–stimulation to the common peroneal nerve, has received the positive endorsement of Westmead Hospital, New South Wales, as an important new development in the prevention of Deep Vein Thrombosis (DVT).

18 Mar 2012

3 million Australians to develop diabetes by 2025

According to the latest figures, one in three of today's young Australians will go on to develop diabetes. A new assessment of national health data released by Diabetes Australia today shows 1.5 million Australians currently have diabetes. It says the diabetes rate is likely to at least double in Australia over the next decade, and predicts 3 million people will have type 2 diabetes by 2025.

18 Mar 2012

Study of genes may hold the key to improved skin care

Ever wonder why two people who are the same age may look years apart? While extrinsic factors such as sun exposure and smoking can contribute to skin aging, intrinsic factors - namely the genes inherited from our parents - can have an even greater influence on how our skin ages.

17 Mar 2012

Exposure to MEHP shortens reproductive life of female mice

Female mouse fetuses exposed to very high doses of a common industrial chemical that makes plastics more pliable develop significant reproductive alterations and precancerous lesions as they grow up, according to a new toxicology study conducted at Brown University.

17 Mar 2012

FDA approves IDE for HeartWare 'ADVANCE' bridge-to-transplant clinical trial

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced that the U.S. Food and Drug Administration has approved an IDE Supplement that allows HeartWare to enroll a fourth allotment, of 54 additional patients, in its "ADVANCE" bridge-to-transplant clinical trial under a Continued Access Protocol.

17 Mar 2012

Gamma Knife surgery stops growth of 'World's tallest living human'

Sultan Kosen won't be posting new world records for height anymore, but that's just fine with him. The Gamma Knife radiosurgery the 29-year-old Turkish man had in August 2010 has successfully stopped his growth at the height of 8 ft 3 in (251 cm). Mr. Kosen, who suffered the effects of acromegaly, has held the title of "World's Tallest Living Human" since September 2009, when his 8 ft plus stature edged 7 ft 9 in Xiu Xung from China.

From Elekta 17 Mar 2012

Japan's MHLW provides reimbursement coverage for MTWA test

Cambridge Heart, Inc., a developer of non-invasive diagnostic tests for cardiac disease, today announced that its Microvolt T-Wave Alternans (MTWA) test received reimbursement coverage from Japan's Ministry of Health, Labor and Welfare (MHLW).

17 Mar 2012

Researchers report higher price tag for robotic prostatectomy surgery

In perfecting the science of medicine, advancements always face exhaustive scrutiny and opposition. Typically, these rigors focus on confirming the efficacy of a procedure or treatment to ensure it remains in the patient's best interest for healing or wellness. More recently, with heightened emphasis on government-funded healthcare, medical procedures such as robotic prostatectomy surgery for prostate cancer treatment are under fire for cost.

17 Mar 2012

Lilly Oncology, NCCS to launch 2012 art competition and exhibition

Get your canvases, paintbrushes and cameras ready -- the subject is cancer and you are the storyteller. Lilly Oncology and the National Coalition for Cancer Survivorship (NCCS) today announced the launch of the 2012 Lilly Oncology On Canvas: Expressions of a Cancer Journey Art Competition and Exhibition.

17 Mar 2012

Clinicians to discuss best approaches for future cancer treatment at Brainlab's radiotherapy meeting

Today clinicians from around the world will gather at the 4th Brainlab European Radiotherapy User Meeting to share their best practice and experiences in treating difficult-to-treat cancers using advanced radiotherapy.

17 Mar 2012

BC BS of Florida retires negative medical policy for FeNO testing

Aerocrine AB announces that BlueCross BlueShield (BC BS) of Florida1 has retired/archived their negative medical policy for FeNO testing. The change is effective March 15, 2012.

17 Mar 2012

Minn. bill would require hospitals to disclose 'futility policies;' Other hospital news

Meanwhile, in Florida, public hospitals are looking at massive layoffs to save money.

17 Mar 2012

SBMT announces 2012 recipients of Pioneers in Medicine, Technology and Healthcare Policy Awards

Today, the Society for Brain Mapping & Therapeutics announced the 2012 recipients of the organization's prestigious Pioneers in Medicine, Technology, and Healthcare Policy Awards.

17 Mar 2012

Oral BRAF inhibitor can extend survival to 16 months for patients with MM

An international team of researchers from the United States and Australia, including researchers at Moffitt Cancer Center in Tampa, Fla., have found that the oral BRAF inhibitor vemurafenib (PLX4032) when tested in a phase II clinical trial offered a high rate of response in patients with previously treated metastatic melanoma and who had the BRAF mutation.

17 Mar 2012