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MAPKAP kinase 2 plays an important role in progression of GIST

Gastrointestinal stroma tumours (GIST) are a very particular challenge for cancer research. For once the tumours, which are mostly located in the stomach, are relatively rare (approx. 100 new cases/year in Austria) and hence are difficult to research. On the other side its behaviour varies quite a lot. While some GIST tumours are relatively harmless, others may become metastatic.

15 Mar 2012

New topical gel decreases amount of time needed to treat actinic keratosis

A new topical gel now available by prescription significantly decreases the amount of time needed to treat actinic keratosis, a skin condition that is a common precursor to skin cancer, according to a multi-center trial led by researchers at Mount Sinai School of Medicine.

15 Mar 2012

Doctors can use genetic profiling to more accurately predict patients with AML

Researchers have identified a set of genetic abnormalities in patients with acute myelogenous leukemia (AML) that doctors can use to more accurately predict patients' prognoses and select treatments that are most likely to benefit them.

15 Mar 2012

Vejthani Hospital offers Unicompartmental Knee Arthroplasty in Thailand

Vejthani Hospital Bangkok offers Unicompartmental Knee Arthroplasty to get better range of motion at Vejthani TJR center, the top international hospital in Thailand.

15 Mar 2012

GWU honors Gladstone investigator with Abraham White Scientific Achievement Award

Gladstone Institutes Senior Investigator Deepak Srivastava, MD has won the prestigious 2012 Abraham White Scientific Achievement Award from The George Washington University. Dr. Srivastava, who directs cardiac and stem cell research at Gladstone will share the award with Dr. Luigina Romani, professor of microbiology at the University of Perugia.

15 Mar 2012

New UCLA Alzheimer's and Dementia Care program for patients, caregivers

Alzheimer's disease affects an estimated 5.4 million people in the U.S., some 480,000 of them in California. Nearly half of all people 85 and older will be stricken with the disease. The overall burden of dementia is still higher, with Alzheimer's accounting for only 60 to 80 percent of dementia cases.

15 Mar 2012

New RAGE inhibitor shows promise against Alzheimer's

Researchers have taken another crack at a promising approach to stopping Alzheimer's disease that encountered a major hurdle last year. In research published this week in the Journal of Clinical Investigation, scientists have developed a compound that targets a molecular actor known as RAGE, which plays a central role in mucking up the brain tissue of people with the disease.

15 Mar 2012

Beating coronary artery bypass surgery may carry an increased likelihood of death

Coronary artery bypass surgery performed whilst the heart is still beating may carry an increased likelihood of death, according to a systematic review by Cochrane researchers.

15 Mar 2012

People with RBD more likely to develop Parkinson's, MCI

People with symptoms suggesting rapid eye movement sleep behavior disorder, or RBD, have twice the risk of developing mild cognitive impairment (MCI) or Parkinson's disease within four years of diagnosis with the sleep problem, compared with people without the disorder, a Mayo Clinic study has found.

15 Mar 2012

AT-1001 shows promise in treating drug addiction

In preclinical studies, researchers at SRI International and Astraea Therapeutics have recently evaluated the role of a new drug receptor target that shows promise for the treatment of drug addiction.

15 Mar 2012

NCAA grant to kick off long-term study of concussion, other head injuries in athletes

A grant from the NCAA will kick off a groundbreaking, long-term study of concussion and other head injuries among athletes, led by University of Michigan researchers and their colleagues around the country.

15 Mar 2012

Exercise training can reduce worry symptoms among GAD patients

This study demonstrates that exercise training, including resistance exercise training, is a feasible, low-risk treatment that can potentially reduce worry symptoms among generalized anxiety disorder (GAD) patients and may be an effective adjuvant, short-term treatment or augmentation for GAD.

15 Mar 2012

Researchers identify epigenetic signatures within reprogrammed skin cells

A research team has identified epigenetic signatures, markers on DNA that control transient changes in gene expression, within reprogrammed skin cells.

15 Mar 2012

New experimental technique can produce cells with specific functions

Researchers at the RIKEN Omics Science Center (OSC) have successfully developed and demonstrated a new experimental technique for producing cells with specific functions through the artificial reconstruction of transcriptional regulatory networks. As an alternative to induced pluripotent stem cells, the technique promises to enable faster and more efficient production of functional cells for use in cancer therapy and a variety of other areas.

15 Mar 2012

One in four HIV patients have been sexually abused as a child

One in four HIV patients was found to have been sexually abused as a child, according to a two-year Duke University study of more than 600 HIV patients. Traumatic childhood experiences were also linked to worse health outcomes among these patients, who are aged 20 to 71.

15 Mar 2012

Dietary cadmium may lead to increased risk of breast cancer

Dietary cadmium, a toxic metal widely dispersed in the environment and found in many farm fertilizers, may lead to an increased risk of breast cancer, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

15 Mar 2012

Low-carb, reduced glycemic load and portion-controlled diets effective for obese children

A new study of three diets with obese children shows that all diets are effective in managing weight but that a reduced glycemic load diet - one that accounts for how many carbs are in the food and how much each gram of carbohydrate raises blood glucose levels - may be most promising.

15 Mar 2012

Researchers discover how Salmonella thrives in the digestive tract

UC Irvine researchers have discovered how Salmonella, a bacterium found in contaminated raw foods that causes major gastrointestinal distress in humans, thrives in the digestive tract despite the immune system's best efforts to destroy it.

15 Mar 2012

Cadherin-23 might play a role in earliest stages of breast cancer metastasis

Rensselaer Polytechnic Institute Biologist Lee Ligon has found a previously unknown connection between breast cancer tumor cells and the surrounding healthy tissue. The results provide new information on the earliest stages of breast cancer metastasis.

15 Mar 2012

Teva commences commercial launch of Escitalopram Oxalate Tablets

Teva Pharmaceutical Industries Ltd. announced today that it has commenced commercial launch of Escitalopram Oxalate Tablets, the Company's generic version of Forest Laboratories' depression and generalized anxiety disorder treatment, Lexapro Tablets.

15 Mar 2012