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Many children with life limiting conditions have been underestimated

The number of children with conditions such as muscular dystrophy, neurodegenerative disorders or severe cerebral palsy who are surviving into adulthood has been underestimated, a new study shows.

12 Mar 2012

Johns Hopkins epidemiologist named Distinguished Service Professor of Medicine

Frederick L. Brancati, M.D., M.H.S., professor of medicine and epidemiology at the Johns Hopkins University School of Medicine and director of Hopkins' division of general internal medicine, was named Distinguished Service Professor of Medicine by the Johns Hopkins University Board of Trustees.

12 Mar 2012

Researchers produce extensive catalog of genes expressed in human islets

A new JDRF-funded study shows that many of the genes known to play a role in type 1 diabetes (T1D) are expressed in pancreatic beta cells, suggesting that the cell responsible for producing insulin may be playing a part in its own destruction to lead to T1D.

12 Mar 2012

FDA denies AstraZeneca Citizen Petitions on SEROQUEL labeling

AstraZeneca today announced that on March 7, 2012, the Food and Drug Administration denied Citizen Petitions requesting that the FDA withhold finally approving any generic quetiapine product with labeling that omits certain hyperglycemia warning language that the FDA required AstraZeneca to include in the labeling for SEROQUEL (quetiapine fumarate) tablets and SEROQUEL XR (quetiapine fumarate) extended-release tablets.

12 Mar 2012

HSS summit: Current classification system for osteoarthritis is inadequate

A recent summit that brought together international multidisciplinary experts has provided a foundation for addressing what is the leading cause of disability in the United States: osteoarthritis.

12 Mar 2012

DeSyRe develops new design techniques for future Systems-on-Chips

For pacemakers and other implantable medical devices there are three key factors: extreme reliability, small size, and long longevity. In the EU project DeSyRe, researchers tackle these issues with a new approach: building a reliable system on unreliable components. Ioannis Sourdis, project leader, today explains the DeSyRe's approach in a tutorial on "Hardware and software design and verification for safety critical electronic systems" during the DATE 2012 conference in Dresden.

12 Mar 2012

PXR protein can protect against cardiovascular disease

Researchers from Queen Mary, University of London and the University of Surrey have found a protein inside blood vessels with an ability to protect the body from substances which cause cardiovascular disease.

12 Mar 2012

TGen to present new research about multiple myeloma at AzMN conference

The Translational Genomics Research Institute (TGen) will present new research about the blood-cell cancer known as multiple myeloma at a free public conference hosted by the Arizona Myeloma Network.

12 Mar 2012

Tranylcypromine shows promise against AML

A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more common types of AMLs.

12 Mar 2012

New Burn Medical Education app for physicians, students

A newly released mobile app designed to educate medical students, physicians and health care workers around the globe on how to care for burn victims is one of a fast-growing number of medical apps being developed at Johns Hopkins Medicine.

12 Mar 2012

TSRI, OPKO Health to develop and commercialize SR 3306 for Parkinson's

OPKO Health, Inc. and The Scripps Research Institute today announced a global agreement for the development and commercialization of SR 3306, a novel compound discovered by scientists from the Florida campus of The Scripps Research Institute that blocks the destruction of brains cells in animal models of Parkinson's disease.

12 Mar 2012

UCSD now offer novel weight-loss surgery, gastric plication

Patients seeking a weight-loss surgery that does not require an implanted device or permanent change to their anatomy, have a new clinical trial option at UC San Diego Health System. Santiago Horgan, MD, chief of minimally invasive surgery, and his team, now offer gastric plication, a novel surgery that folds the stomach into a smaller, more compact size.

12 Mar 2012

HIPK2 regulator protein plays a crucial role in kidney fibrosis

Researchers from Mount Sinai School of Medicine have identified a regulator protein that plays a crucial role in kidney fibrosis, a condition that leads to kidney failure. Finding this regulator provides a new therapeutic target for the millions of Americans affected by kidney failure. The research is published in the March 11 issue of Nature Medicine.

12 Mar 2012

OSU researchers use carbon nanotubes to increase the speed of biological sensors

Researchers at Oregon State University have tapped into the extraordinary power of carbon "nanotubes" to increase the speed of biological sensors, a technology that might one day allow a doctor to routinely perform lab tests in minutes, speeding diagnosis and treatment while reducing costs.

12 Mar 2012

Overweight, aging do not appear to impact mental well-being

Growing older and being overweight are not necessarily associated with a decrease in mental well-being, according to a cross-cultural study looking at quality of life and health status in the US and the UK.

12 Mar 2012

Conference highlights studies on metabolism, aging and monarch butterfly migration

The Genetics Society of America's 53rd Annual Drosophila Research Conference, March 7-11 at the Sheraton Chicago Hotel & Towers, will showcase diverse efforts to understand basic biological processes through the easy-to-study fruit fly, Drosophila melanogaster, and other insects.

12 Mar 2012

BfArM grants Moberg Derma approval to initiate Limtop clinical phase I trial for actinic keratosis

The German- Federal Institute for Drugs and Medical Devices (BfArM) has granted Moberg Derma approval to initiate a clinical phase I trial for Limtop. Limtop is an innovative formulation of an immunomodulatory compound with potential to treat actinic keratosis, genital warts and basal cell carcinoma.

11 Mar 2012

New ways of delivering personalized cancer therapies in a cost effective manner

As scientists continue making breakthroughs in personalized cancer treatment, delivering those therapies in the most cost effective manner has become increasingly important. Now researchers at the University of Colorado School of Medicine have identified new ways of doing just that, allowing more patients to benefit from this revolution in cancer care.

11 Mar 2012

Implant to assume function of damaged venous valves

If heart valves don't close properly, they are replaced. Conventional treatment of venous valve failure, however, has up to now always and exclusively been via medication. In future, an implant will assume the function of damaged valves - and a new dispensing tool means these prostheses can be made using an automated process.

11 Mar 2012

South Africa's evolving HIV/AIDS policy

In this interview in World Politics Review's "Trend Lines," Peter Navario, an adjunct associate professor of public policy at New York University and a former global health fellow at the Council on Foreign Relations, discusses the evolution South Africa's HIV/AIDS policy over the last decade, the country's current relationship with pharmaceutical companies, and how South African President Jacob Zuma's HIV/AIDS policy is received in the region and by international donors.

10 Mar 2012