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Researchers define new treatment for potentially fatal lung disease in patients with CVID

A team of researchers at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute defined a new treatment for a potentially fatal lung disease in patients with a primary immunodeficiency known as common variable immunodeficiency (CVID).

1 Sep 2012

Study may spur research into multi-model imaging based biomarker development for AD

Alzheimer's disease (AD) is one of the most common brain disorders, with an estimated 35 million people affected worldwide. In the last decade, research has advanced our understanding of how AD affects the brain. However, diagnosis continues to rely primarily on neuropsychological tests which can only detect the disease after clinical symptoms begin. In a supplement to the Journal of Alzheimer's Disease, investigators report on the development of imaging-based biomarkers that will have an impact on diagnosis before the disease process is set in motion.

31 Aug 2012

Study reports flaws in design, analysis, and interpretation of Lyme disease

Most doctors treat Lyme disease with antibiotics for two to four weeks after diagnosis, but if symptoms persist after that, medical guidelines recommend against antibiotic retreatment. That recommendation may not be warranted. A newly published statistical review of the four studies upon which those guidelines are based reports flaws in design, analysis, and interpretation that call into question the strength of the evidence against retreatment.

31 Aug 2012

Well-known protein plays central role in development of acute pancreatitis

There is now a clear target for the treatment of acute pancreatitis, according to researchers at Lund University in Sweden, who have discovered that a well-known protein plays a central role in the development of the disease. It is likely that the protein is also highly significant for other inflammatory diseases.

31 Aug 2012

VLST, Pfizer enter in-licensing agreement for anti-CD40 monoclonal antibody

VLST Corporation, a Seattle-based biotechnology company focused on the development of therapeutics for cancer and autoimmune and inflammatory disorders, today announced an in-licensing agreement with Pfizer Inc. for an anti-CD40 monoclonal antibody.

31 Aug 2012

Research identifies new pathway to target with anti-inflammatory drugs

Scientists' discovery of an important step in the body's process for healing wounds may lead to a new way of treating inflammation.

31 Aug 2012

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Transition Therapeutics Inc. today announced that its licensing partner, Elan Corporation, plc has commenced a Phase 2, placebo-controlled, safety and efficacy study of oral ELND005 as an adjunctive maintenance treatment in patients with Bipolar I Disorder (BPD 1) to delay the time to occurrence of mood episodes.

31 Aug 2012

Non-pain-related factors predict long-term opioid use after surgery

Non-pain-related factors—including previous use of pain medications, high perceived risk of addiction, and symptoms of depression—increase the risk of continuing to use strong pain-relieving drugs several months after surgery, reports a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

31 Aug 2012

U.S. behind France, Germany, U.K. in stopping preventable deaths

The study, published in Health Affairs, pointed the finger at the lack of health insurance -- as well as conditions such as hypertension and medical errors -- in the U.S. as part of the problem.

31 Aug 2012

Study explains why some cancer vaccines are not as effective as hoped

A research report published in the September 2012 issue of the Journal of Leukocyte Biology offers a possible explanation of why some cancer vaccines are not as effective as hoped, while at the same time identifies a new therapeutic strategy for treating autoimmune problems. In the report, scientists suggest that cancer, even in the very early stages, produces a negative immune response from dendritic cells, which prevent lymphocytes from working against the disease.

31 Aug 2012

New research about brain and related disorders to be unveiled at Neuroscience 2012

New research about the brain and related disorders will be unveiled at Neuroscience 2012 in New Orleans, Oct. 13-17. Findings will include how the brain weighs complex decisions; progress being made in treating Alzheimer's disease, spinal cord injury, and traumatic brain injury; and novel understanding of how life experiences, diet, and sleep influence brain health and wellness.

31 Aug 2012

Lance Armstrong Foundation, SmartBrief launch new weekly digital media news service

SmartBrief, Inc. launched a weekly digital media news service today in partnership with the Lance Armstrong Foundation.

31 Aug 2012

S107 drug can prevent learning and memory deficits associated with stress-related disorders

Columbia University Medical Center (CUMC) researchers have identified a potential medical treatment for the cognitive effects of stress-related disorders, including post-traumatic stress disorder (PTSD).

31 Aug 2012

Glaucoma and cell death: an interview with Dr. Vivek Gupta

Glaucoma is normally caused by increased pressure of aqueous humour fluid in the eye. A defining feature of this disease is destruction of a particular type of cells in the retina called retinal ganglion cells and excavation of the optic disc region.

31 Aug 2012

Type 2 diabetics with normoalbuminuria more likely to develop heart problems

In individuals with type 2 diabetes, any degree of measurable urinary protein excretion—even in what is considered the normal range—increases their risk of experiencing heart problems, according to a study appearing in an upcoming issue of new study in the Journal of the American Society of Nephrology (JASN).

31 Aug 2012

Weill Cornell Medical College receives three new research grants for translational blood cancer study

Weill Cornell Medical College has been awarded three new research grants from the Leukemia & Lymphoma Society totaling $1.8 million. The funds will support critically-needed translational research for blood cancers, accelerating promising discoveries from the laboratory to the patient's bedside.

31 Aug 2012

Impulsive and compulsive personality traits linked with traumatic upbringing during childhood

Previous research has shown that personality traits such as impulsivity or compulsiveness are indicators of an increased risk of addiction. Now, new research from the University of Cambridge suggests that these impulsive and compulsive personality traits are also associated with a traumatic upbringing during childhood.

31 Aug 2012

Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

Patients with uncontrolled renovascular hypertension saw a significant improvement in their blood pressure with renal artery stent deployment. The multicenter HERCULES trial, evaluating the safety and effectiveness of the RX Herculink Elite Stent, found that patients with higher blood pressure levels at baseline had the most dramatic reduction in blood pressure following intervention.

31 Aug 2012

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Ironwood Pharmaceuticals, Inc. and Forest Laboratories, Inc. announced today that LINZESS (linaclotide) was approved by the U.S. Food and Drug Administration (FDA) as a once-daily treatment for adult men and women suffering from irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC).

31 Aug 2012

Studies examine how PML gene regulates the fatty acid oxidation pathway

Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer treatment.

31 Aug 2012

Medical Condition News

Researchers define new treatment for potentially fatal lung disease in patients with CVID

Study may spur research into multi-model imaging based biomarker development for AD

Study reports flaws in design, analysis, and interpretation of Lyme disease

Well-known protein plays central role in development of acute pancreatitis

VLST, Pfizer enter in-licensing agreement for anti-CD40 monoclonal antibody

Research identifies new pathway to target with anti-inflammatory drugs

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Non-pain-related factors predict long-term opioid use after surgery

U.S. behind France, Germany, U.K. in stopping preventable deaths

Study explains why some cancer vaccines are not as effective as hoped

New research about brain and related disorders to be unveiled at Neuroscience 2012

Lance Armstrong Foundation, SmartBrief launch new weekly digital media news service

S107 drug can prevent learning and memory deficits associated with stress-related disorders

Glaucoma and cell death: an interview with Dr. Vivek Gupta

Type 2 diabetics with normoalbuminuria more likely to develop heart problems

Weill Cornell Medical College receives three new research grants for translational blood cancer study

Impulsive and compulsive personality traits linked with traumatic upbringing during childhood

Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Studies examine how PML gene regulates the fatty acid oxidation pathway

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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