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Induced hyperammonaemia increases daytime sleepiness in patients with cirrhosis

Italian and Swiss researchers confirm that induced hyperammonaemia significantly increases daytime sleepiness in patients with cirrhosis. The findings available in the March issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, show that higher blood levels of ammonia reduced the ability of cirrhotic patients to produce restorative sleep.

2 Mar 2012

Study: Kidney donors at no increased risk of heart disease

There is good news for the 27,000 plus people around the world who donate a kidney each year. A study which followed living kidney donors for 10 years found that they were at no greater risk for heart disease than the healthy general population.

2 Mar 2012

Ekso Bionics, Kessler Foundation partner to test commercial robotic exoskeleton

On Monday, Kessler Foundation became the second rehabilitation research center in the U.S. to implement Ekso, a wearable, robotic battery-powered exoskeleton that allows wheelchair users with lower-extremity weakness to stand and walk.

2 Mar 2012

NexGen receives U.S. patent allowance for novel pathogenesis based seizure treatment

NexGen Biomedical, Inc.'s Founder has received a Notice of Allowance from the US Patent Office for a novel treatment method for seizures.

2 Mar 2012

CSL Behring to receive 2012 EURORDIS Award for pioneering work

CSL Behring is the recipient of a 2012 EURORDIS Award for its pioneering work in developing and manufacturing therapies used to treat rare and serious medical conditions.

2 Mar 2012

p14 ARF protein also regulates tumor-induced angiogenesis

Researchers at Winship Cancer Institute of Emory University have identified a new function for a gene that normally prevents the development of cancer.

2 Mar 2012

Four leading organizations release recommendations to ensure optimal care of TAVR patients

Four leading heart organizations representing cardiologists and cardiothoracic surgeons released initial recommendations today for creating and maintaining transcatheter aortic valve replacement (TAVR) programs.

2 Mar 2012

KI receives additional fund for research into bicuspid aortic valve

Researchers at Karolinska Institutet have received an additional 1.4 million Euro from business magnate Fredrik Lundberg for research into bicuspid aortic valve and its links to aneurysm.

1 Mar 2012

Scientists identify genetic defect responsible for TAR Syndrome

Universitätsmedizin Berlin in collaboration with the Sanger Institute in Cambridge and other cooperation partners in Belgium, the Netherlands and France, were able to identify a genetic defect that is responsible for the development of TAR Syndrome, a congenital malformation of the skeleton and blood.

1 Mar 2012

Mayo researchers gain insights into function of histone chaperones

Mayo Clinic researchers have gained insights into the function of a member of a family of specialized proteins called histone chaperones. Using nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography, they have determined the 3-D structure and interactions of the histone chaperone Rtt106 down to the atomic details.

1 Mar 2012

DRI scientists create novel oxygen-generating material

Scientists at the Diabetes Research Institute have developed a revolutionary technique to provide critical oxygen for maintaining the survival of insulin-producing cells. This is the first time that scientists have been able to successfully deliver oxygen locally to beta cells using a biomaterial.

1 Mar 2012

Metastatic melanoma patients with specific genetic mutation benefit from vemurafenib

A report published this week in the New England Journal of Medicine shows that the 50 percent of metastatic melanoma patients with a specific genetic mutation benefit from the drug Vemurafenib - increasing median survival from about 6 months to 15.9 months. In patients who responded, the drug stopped cancer progression for a median 6.7 months.

1 Mar 2012

1.3 million cancer deaths in 2012 in the EU: Report

New research released this Wednesday shows that almost 1.3 million people will die of cancer in the European Union this year, but death rates from the disease are on a steady decline.

1 Mar 2012

Parkinson's drug Amantadine may help brain injury victims: Study

The study shows that Amantadine helps boost brain levels of dopamine, a neurotransmitter linked to arousal. And for patients who are in a vegetative state following a brain injury, the drug can help -- possibly by improving responsiveness during rehabilitation.

1 Mar 2012

Statins remain important for people at high risk of heart attack or stroke

NPS is urging people taking statins to continue to take their medicine as prescribed and to see their doctor if they are unsure about the benefit of the medicine for them.

1 Mar 2012

Physiological problems stemming from concussions may persist

A study recently published by the University of Kentucky's Scott Livingston shows that physiological problems stemming from a concussion may continue to present in the patient even after standard symptoms subside.

1 Mar 2012

New method for creating nanofibers could improve drug delivery methods

A new method for creating nanofibers made of proteins, developed by researchers at Polytechnic Institute of New York University (NYU-Poly), promises to greatly improve drug delivery methods for the treatment of cancers, heart disorders and Alzheimer's disease, as well as aid in the regeneration of human tissue, bone and cartilage.

1 Mar 2012

Software transmits brain wave data for instant analysis

What if a computer chip in a football player's helmet could tell coaches on the sideline that he has suffered a concussion?

1 Mar 2012

New robotic surgical system can treat early-stage lung cancer

In a Canadian first, thoracic surgeons at Toronto General Hospital, University Health Network used a robotic surgical system to treat early-stage lung cancer by removing the cancer, along with a lobe of the lung. The use of this system improves outcomes after surgery and will expand the numbers of patients who can benefit from this type of minimally invasive surgical treatment.

1 Mar 2012

Cyclotides discovery may open up new possibilities for immune suppression

A team of researchers at the MedUni Vienna, together with scientists from the University Hospital of Freiburg, has decoded a mechanism in cyclic plant peptides, known as cyclotides, from the family of coffee plants (Rubiaceae) that could open up new possibilities for immune suppression.

1 Mar 2012