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AGS honors IU professor for outstanding achievement in geriatric care

In recognition of his significant contributions to the health care of older adults, Regenstrief Institute investigator Malaz Boustani, M.D., MPH, associate professor of medicine at the Indiana University School of Medicine, will receive the 2012 American Geriatrics Society Outstanding Scientific Achievement for Clinical Investigation Award.

15 Feb 2012

Study: ACL injury mechanism involves combination of factors

Landing from a jump can cause a non-contact anterior cruciate ligament (ACL) injury. But evidence presented at the Orthopaedic Research Society 2012 Annual Meeting demonstrates that the injury mechanism that causes that ACL injury involves a combination of factors rather than a single factor as some have claimed.

15 Feb 2012

First large-scale investigation into diabetes risk among young people in South Asia

Scientists at King's College London and the National Diabetes Centre (Sri Lanka) have found evidence of a high number of risk factors for type 2 diabetes among the young urban population in Sri Lanka. The study is the first large-scale investigation into diabetes risk among children and young people in South Asia, and provides further evidence that the region is rapidly becoming a hotspot in the growing international diabetes epidemic.

14 Feb 2012

Cartilage graft can stimulate bone regeneration

A person has a tumor removed from her femur. A soldier is struck by an improvised explosive device and loses a portion of his tibia. A child undergoes chemotherapy for osteosarcoma but part of the bone dies as a result.

14 Feb 2012

Nilvadipine phase III trial for Alzheimer's launches in Europe

A research team today announced the launch of a European large-scale clinical trial of Nilvadipine, an Alzheimer's disease drug developed at the Roskamp Institute in Sarasota.

14 Feb 2012

Juvenile arthritis affected kids are at a high risk of cancer: Study

A new study shows that kids with juvenile idiopathic arthritis develop cancer four times more often than children without the disease, but the treatments they receive - including biologic treatments like Enbrel - may not explain their increased risk. If confirmed, researchers say the findings should ease fears that biologic treatments known as TNF inhibitors cause cancer in children and young adults.

14 Feb 2012

Epigenetic mechanisms maintain tolerance in T cells specific for self antigens

At the most basic level, the immune system must distinguish self from non-self, that is, it must discriminate between the molecular signatures of invading pathogens (non-self antigens) and cellular constituents that usually pose no risk to health (self-antigens).

14 Feb 2012

Kowa announces data of LIVALO vs. Crestor on pharmacodynamics of warfarin

Kowa Pharmaceuticals America, Inc. today announced data assessing the effect of LIVALO (pitavastatin) compared with Crestor (rosuvastatin) on steady-state pharmacodynamics (PD) of warfarin by measuring international normalized ratio (INR) in healthy adult subjects.

14 Feb 2012

New light on treatment targets for potentially life-threatening cardiac arrhythmia conditions

That flutter in your heart may have more to do with the movement of sodium ions than the glance of a certain someone across a crowded room.

14 Feb 2012

'Targeted' drugs may be effective against lung and colorectal tumors driven by novel gene abnormalities

Novel gene abnormalities discovered in a subpopulation of lung and colorectal tumors could potentially identify patients with a good chance of responding to highly specific "targeted" drugs already in use for treating other cancers, scientists report.

14 Feb 2012

Healthy, loving relationship is good for the heart

Being involved in a healthy, loving relationship is good for the heart, says Vanderbilt Heart and Vascular Institute cardiologist Julie Damp, M.D.

14 Feb 2012

Machine-learning methods show that patients with severe brain injury could communicate accurately

Only by employing complex machine-learning techniques to decipher repeated advanced brain scans were researchers at NewYork-Presbyterian/Weill Cornell able to provide evidence that a patient with a severe brain injury could, in her way, communicate accurately.

14 Feb 2012

Prevention and treatment options are improving long-term outcomes for heart failure

"Despite the increasing number of people affected, the prognosis for patients with heart failure has steadily improved," said Gregg C. Fonarow, M.D, chairman of American Heart Association Hospital Accreditation Science Committee and professor of cardiovascular medicine of the University of California, Los Angeles.

14 Feb 2012

Switching from calorie-laden beverages to water can help lose weight

Making a simple substitution of water or diet soft drinks for drinks with calories can help people lose 4 to 5 pounds, a new University of North Carolina at Chapel Hill study shows.

14 Feb 2012

Radiation treatment transforms breast cancer stem cells into new iBCSCs

Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don't respond well to chemotherapy.

14 Feb 2012

Second and third generation Mexican-Americans more likely to be obese

A University of South Carolina study shows that Mexican-American youth gain pounds as they move away from the dietary habits of their native country, a move that is putting them at risk for serious health problems.

14 Feb 2012

Ensysce announces latest data on delivery platform for therapeutic siRNA

Ensysce Biosciences Inc. announced today the publication of their latest data on their delivery platform for short interfering RNA (siRNA) for therapeutic purposes in the journal Materials.

14 Feb 2012

Stress protein effectively activates replication of HBV in liver cells

People who have received a donor organ need lifelong immunosuppressant drugs to keep their immune system from attacking the foreign tissue. However, with a suppressed immune system, many infectious agents turn into a threat. Infections such as with human cytomegalovirus and a certain type of human polyomavirus frequently cause complications in transplant recipients.

14 Feb 2012

Merck Serono, Mendor sign blood glucose meter distribution agreement

Mendor, the Finnish diabetes technology company, continues its rapid growth and is excited to announce yet another international partnership - now opening the United Kingdom for its innovative products. Mendor has just signed a distribution agreement with a leading pharmaceutical company in the Diabetes field Merck Serono, covering the United Kingdom diabetes market.

14 Feb 2012

Knee replacements double in 10 years, study says

More than 4 million Americans over 50 have artificial knees, according to a new study. ... "These data are sobering because we didn't know what an army of people we've created over the last decade," said study author Elena Losina, co-director of the Orthopedics and Arthritis Center for Outcomes Research at Harvard's Brigham and Women's Hospital. ... Artificial knees also wear out after a period of time, so as the operations are increasingly done on younger Americans, many will live long enough to almost certainly need a second or even third knee replacement.

14 Feb 2012