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Strong link between high HuR protein levels and malignancy of HCC

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation.

27 Jan 2012

Mass. Eye and Ear cornea specialist wins RPB Senior Scientific Investigator Award

Research to Prevent Blindness (RPB) has granted Massachusetts Eye and Ear Infirmary cornea specialist James Chodosh, M.D., M.P.H., a $150,000 Senior Scientific Investigator Award. RPB Senior Scientific Investigator Awards support nationally recognized scientists conducting eye research at medical institutions in the United States.

27 Jan 2012

Muscle endurance tests can detect abnormalities in early stages of MS

Multiple sclerosis (MS), a neurodegenerative disease, causes periodic attacks of neurologic symptoms such as limb weakness and mobility defects. And while MS patients' walking abilities and muscle strength are examined on a regular basis, doctors have yet to determine when the lower limb muscles begin to deteriorate.

27 Jan 2012

Technoclone, Roche enter strategic alliance to co-develop coagulation assays

Roche announced today that it has entered into a strategic alliance with Technoclone, a reagent specialist in thrombosis and cardiovascular diagnostics based in Vienna, Austria, to co-develop a complete range of coagulation assays.

From Roche Sequencing and Life Science 27 Jan 2012

New links between leukemia cells and osteoblasts

University of Rochester Medical Center researchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukemia.

27 Jan 2012

Routine PET/CT scan use in head and neck cancer patients can detect local recurrences

Routine use of positron emission tomography/computed tomography (PET/CT) scans in head and neck cancer patient follow-up can detect local recurrences before they become clinically apparent and may improve the outcome of subsequent salvage therapy, according to a study presented at the Multidisciplinary Head and Neck Cancer Symposium, sponsored by AHNS, ASCO, ASTRO and SNM.

27 Jan 2012

Boehringer Ingelheim initiates two afatinib phase III trials in head and neck cancer

Boehringer Ingelheim announced today the initiation of two phase III clinical trials, LUX-Head & Neck 1 and LUX-Head & Neck 2. These trials evaluate afatinib in patients with metastatic and recurrent head and neck cancer, and in patients with locally advanced disease, respectively.

27 Jan 2012

LEO Pharma receives FDA approval for Picato topical gel to treat AK

LEO Pharma announced today that the U.S. Food and Drug Administration (FDA) approved Picato (ingenol mebutate) gel (0.015%, 0.05%) for the topical treatment of actinic keratosis.

27 Jan 2012

FDA approves UCB's Keppra for treatment of partial onset seizures in infants

UCB announced today that the U.S. Food and Drug Administration (FDA) has approved Keppra (levetiracetam) tablets and oral solution as adjunctive therapy in the treatment of partial onset seizures in adults and children one month of age and older with epilepsy.

27 Jan 2012

New consensus guidelines for treatment of plaque psoriasis

To assist the millions of Americans living with psoriasis, the most common autoimmune disease in the country, the National Psoriasis Foundation published the most recent guidelines in the United States for the management of plaque psoriasis—the most prevalent form of the disease, affecting roughly 80 percent of people with psoriasis.

26 Jan 2012

Psychiatric disorders definitions to be revised

The definition of depression is proposed to be changed and now the diagnosis would characterize grieving as a disorder and greatly increase the number of people treated for it.

26 Jan 2012

Breakthroughs in Alzheimer’s disease research

Researchers are closer to understanding Alzheimer’s disease using a new stem cell technique. They have successfully replicated Alzheimer’s disease neurons with stem cells for the first time.

26 Jan 2012

Bacon for nosebleeds: Case report

Ian Humphreys, Sonal Saraiya, Walter Belenky and James Dworkin, at Detroit Medical Centre in Michigan proceeded to treat a four year old girl who had a rare hereditary disorder that brings prolonged bleeding, publishing their findings in the Annals of Otology, Rhinology and Laryngology.

26 Jan 2012

Amorcyte commences enrollment in PreSERVE Phase 2 trial for acute myocardial infarction

Amorcyte, LLC, a NeoStem, Inc. company today announces the enrollment of the first patient in the Amorcyte PreSERVE Phase 2 trial for acute myocardial infarction.

25 Jan 2012

Oramed receives Australian patent for core technology in oral delivery of peptides

Marking a major milestone for the Company, Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has received approval for a key patent by the Australian Patent Office.

25 Jan 2012

Society for Endocrinology BES conference to take place March 19-22

The annual Society for Endocrinology BES conference is taking place in Harrogate, UK from 19-22 March 2012.

25 Jan 2012

UCSF team develops methods that may help predict brain tumor recurrence

After people with low-grade glioma, a type of brain cancer, undergo neurosurgery to remove the tumors, they face variable odds of survival - depending largely on how rapidly the cancer recurs. Even though their doctors monitor the tumor closely with sophisticated imaging, it is difficult to determine with certainty whether cancer has returned in a more malignant state that requires aggressive treatment.

25 Jan 2012

Panel releases draft priorities for comparative effectiveness research

The draft, which offered insight into the Patient-Centered Outcomes Research Institute's priorities and research agenda, did not single out any specific diseases or treatments. The Institute did seek public comment.

25 Jan 2012

CHF associated with reduced patency after peripheral endovascular intervention

Congestive heart failure (CHF) is a highly prevalent comorbidity among patients with symptomatic peripheral arterial disease. The effect of CHF on the procedural success of endovascular treatment, however, remains unknown.

25 Jan 2012

Society of Toxicology 51st Annual Meeting and ToxExpo to be held March 11-15

More than 7,000 toxicologists from every corner of the globe are expected to attend the Society of Toxicology (SOT) 51st Annual Meeting and ToxExpo-, which will highlight toxicology's crucial role in creating a safer and healthier world. The five-day meeting will take place at the Moscone Convention Center in San Francisco from March 11-15, 2012.

25 Jan 2012