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New data from TetraLogic's TL32711 study on AML presented at 53rd ASH meeting

TetraLogic Pharmaceuticals, a biopharmaceutical company developing novel small molecule Smac mimetic drugs to treat cancer, today announced the oral presentation of new data on its Smac mimetic drug candidate TL32711 at the 53rd ASH Annual Meeting and Exposition in San Diego.

12 Dec 2011

HER2 proteins do not predict breast cancer patient's outcome after Herceptin treatment

Precisely quantifying the amount of three different HER growth proteins, along with several other proteins believed linked to breast cancer, did not predict a patient's outcome after treatment for HER2-Positive Breast Cancer with Herceptin, say Mayo Clinic researchers.

12 Dec 2011

ACE inhibitors, ARBs have different effects on heart health of dialysis patients

Two seemingly similar blood pressure-lowering drugs have different effects on the heart health of dialysis patients, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

12 Dec 2011

Gene therapy can reduce painful bleeding episodes in patients with hemophilia B

Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U.K.

12 Dec 2011

People in Northern Ireland less likely to develop cancers

People in Northern Ireland have a lower risk of developing some cancers than those living in the Republic of Ireland, according to the All-Ireland Cancer Atlas - a collaborative publication by the Northern Ireland Cancer Registry at Queen's University Belfast and the National Cancer Registry in Cork.

12 Dec 2011

Study describes miR-124 can prevent and treat liver cancer

Cancer of the liver - rare in the United States but the third-leading cause of cancer death worldwide - can result from environmental exposures or infections like chronic hepatitis, but the link is poorly understood.

12 Dec 2011

New method to design Alzheimer's antibodies

Researchers at Rensselaer Polytechnic Institute have developed a new method to design antibodies aimed at combating disease. The surprisingly simple process was used to make antibodies that neutralize the harmful protein particles that lead to Alzheimer's disease.

12 Dec 2011

Most patients with AKI do not see kidney specialists within a year

Most patients with an abrupt kidney injury that does not get better do not see a kidney specialist within a year, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

12 Dec 2011

Memgen to present ISF35 clinical trial data on CLL at 53rd ASH meeting

Memgen, LLC announces the following abstract on ISF35, the Company's lead product, will be presented during the 53rd Annual Meeting of the American Society of Hematology (ASH) in San Diego, CA.

12 Dec 2011

Positive data from Aeterna Zentaris AEZS-131 preclinical study on TNBC

Aeterna Zentaris Inc. today announced positive preclinical data in triple-negative breast cancer (TNBC) for its highly selective Erk 1/2 inhibitor anticancer compound, AEZS-131.

11 Dec 2011

Researchers discover molecular marker for immediate precursors of blood stem cells

A research team led by Nancy Speck, PhD, professor of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, has discovered a molecular marker for the immediate precursors of hematopoietic (blood) stem cells (HSCs) in the developing embryo, which provides much-needed insights for making these cells from engineered precursors.

9 Dec 2011

Bluegrass Vascular commences enrollment in clinical study of Surfacer Inside-Out Access Catheter System

Bluegrass Vascular Technologies, a medical technology company focused on life-saving devices and methods for vascular access procedures, has announced patient enrollment in the first clinical study of its Surfacer Inside-Out Access Catheter System, a proprietary system that allows physicians to perform a novel "inside-out" approach to gain venous access.

9 Dec 2011

Signal Genetics to launch second generation Myeloma product, MyPRS Plus

Signal Genetics announced today, at the American Society of Hematology Annual Meeting, that the Company is launching its next generation Multiple Myeloma product, MyPRS Plus, effective January 1, 2012.

9 Dec 2011

Increased sensitivity to low frequency vibration found in people with inherited hearing loss

People with a certain form of inherited hearing loss have increased sensitivity to low frequency vibration, according to a study by Professor Thomas Jentsch of the Leibniz-Institut f-r Molekulare Pharmakologie (FMP)/Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and Professor Gary Lewin (MDC), conducted in cooperation with clinicians from Madrid, Spain and Nijmegen, the Netherlands.

9 Dec 2011

Study explains molecular basis for cherubism disease

The Samuel Lunenfeld Research Institute's Drs. Frank Sicheri, Tony Pawson and Sebastian Guettler, in collaboration with Dr. Robert Rottapel at the Ontario Cancer Institute, have uncovered the detailed architecture of a crucial component of Tankyrase, a protein linked to the bone development disorder cherubism and involved in a myriad of cellular processes.

9 Dec 2011

Abbott commences Absorb-XIENCE PRIME comparative clinical trial

Abbott today announced the initiation of ABSORB II, the first randomized, controlled, multi-center clinical trial to evaluate the safety, efficacy and performance of the Absorb™ bioresorbable vascular scaffold (BVS) compared to the company's XIENCE PRIME™ Everolimus Eluting Coronary Stent System.

9 Dec 2011

Researchers reveal contribution of telomerase in controlling genetic code integrity

Researchers have revealed how a molecule called telomerase contributes to the control of the integrity of our genetic code, and when it is involved in the deregulation of the code, its important role in the development of cancer.

9 Dec 2011

Trastuzumab improves long-term outcomes in obese patients with HER2-positive breast cancer

A large, multicenter, randomized study has shown that obese patients with HER2-positive breast cancer have larger tumors, increased lymph node involvement and, when not treated with trastuzumab, poorer long-term outcomes than normal-weight patients.

9 Dec 2011

Research roundup: Depression and Medicaid spending; Saving on chronic care costs?: Mental health coverage

The researchers looked at treatment of depression in Medicaid enrollees in Florida from 1996-2006. They found a 29 percent increase in spending "despite decreases in inpatient costs." They attributed much of the increase to the growing use of antipsychotic drugs. They concluded that "spending for Medicaid enrollees with depression increased substantially, with minimal improvements in quality of care".

9 Dec 2011

Positive results from Puma's neratinib Phase II trials presented at CTRC-AACR San Antonio Breast Cancer Symposium

Puma Biotechnology, Inc., a development stage biopharmaceutical company, announced that results from ongoing Phase II clinical trials of Puma's investigational drug PB272 (neratinib) were presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium that is currently taking place in San Antonio, Texas.

9 Dec 2011

Medical Condition News

New data from TetraLogic's TL32711 study on AML presented at 53rd ASH meeting

HER2 proteins do not predict breast cancer patient's outcome after Herceptin treatment

ACE inhibitors, ARBs have different effects on heart health of dialysis patients

Gene therapy can reduce painful bleeding episodes in patients with hemophilia B

People in Northern Ireland less likely to develop cancers

Study describes miR-124 can prevent and treat liver cancer

New method to design Alzheimer's antibodies

Most patients with AKI do not see kidney specialists within a year

Memgen to present ISF35 clinical trial data on CLL at 53rd ASH meeting

Positive data from Aeterna Zentaris AEZS-131 preclinical study on TNBC

Researchers discover molecular marker for immediate precursors of blood stem cells

Bluegrass Vascular commences enrollment in clinical study of Surfacer Inside-Out Access Catheter System

Signal Genetics to launch second generation Myeloma product, MyPRS Plus

Increased sensitivity to low frequency vibration found in people with inherited hearing loss

Study explains molecular basis for cherubism disease

Abbott commences Absorb-XIENCE PRIME comparative clinical trial

Researchers reveal contribution of telomerase in controlling genetic code integrity

Trastuzumab improves long-term outcomes in obese patients with HER2-positive breast cancer

Research roundup: Depression and Medicaid spending; Saving on chronic care costs?: Mental health coverage

Positive results from Puma's neratinib Phase II trials presented at CTRC-AACR San Antonio Breast Cancer Symposium

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

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