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Health disparity tends to increase among young U.S. adults

Levels of health disparity have increased substantially for people born in the United States after 1980, according to new research.

2 Dec 2011

Two studies uncover limitations in screening for hepatocellular carcinoma

Two studies available in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, have uncovered limitations in screening for primary liver cancer, also known as hepatocellular carcinoma.

2 Dec 2011

Idera receives FDA notification to proceed with IMO-3100 Phase 2 clinical trial for psoriasis

Idera Pharmaceuticals, Inc. today announced the receipt of verbal notification from the Food and Drug Administration that the company may proceed with a Phase 2 clinical trial of IMO-3100 in patients with psoriasis based on a trial protocol submitted by the company in October 2011.

2 Dec 2011

AVEO, Boehringer Ingelheim enter development and manufacturing agreement for ficlatuzumab

AVEO Pharmaceuticals, Inc. and Boehringer Ingelheim today announced that they have entered into an agreement for large-scale process development and clinical manufacturing of ficlatuzumab, AVEO's novel HGF inhibitory antibody that is currently in Phase 2 clinical development in patients with non-small cell lung cancer.

2 Dec 2011

ADVENTRX, FDA discuss ANX-188 development plans for treatment of sickle cell crisis

ADVENTRX Pharmaceuticals, Inc. announced today that it met with the U.S. Food and Drug Administration (FDA) to review development plans for ANX-188 (purified poloxamer 188), the Company's first-in-class treatment for sickle cell patients experiencing vaso-occlusive crisis.

1 Dec 2011

Positive interim data from Anthera's PEARL-SC phase 2b clinical study in systemic lupus erythematosus

Anthera Pharmaceuticals, Inc., a biopharmaceutical company developing drugs to treat serious diseases associated with inflammation, today announced positive interim biomarker data from the PEARL-SC phase 2b clinical study in patients with systemic lupus erythematosus.

1 Dec 2011

Body's surveillance for cancer causing damage and response to allergies share common pathway

CANCER RESEARCH UK scientists have found that the body's surveillance for cancer causing damage and its response to allergies share a common pathway, according to research published in Science on Thursday.

1 Dec 2011

Insights into causes of Idiopathic Pulmonary Fibrosis

Tracking individual cells within the lung as they move around and multiply has given Duke University researchers new insights into the causes of Idiopathic Pulmonary Fibrosis (IPF) a disease which can only be treated now by lung transplantation.

1 Dec 2011

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

Ceregene, Inc. reported today that it has completed enrollment in its Phase 2b trial of CERE-120, a gene therapy product expressing the neurturin (NRTN) gene for the treatment of Parkinson's disease.

1 Dec 2011

FDA clears Covidien's SpiderFX embolic protection device

Covidien, a leading global provider of healthcare products, today announced that the U.S. Food and Drug Administration (FDA) has cleared SpiderFX for the treatment of severely calcified lesions used in conjunction with plaque excision in arteries of the lower extremities. It is the only embolic protection device indicated for this treatment in the United States.

1 Dec 2011

Auxilium initiates XIAFLEX phase IIa trial in Frozen Shoulder syndrome

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced that the first patient has been dosed in its open-label phase IIa trial of XIAFLEX (collagenase clostridium histolyticum) for the treatment of idiopathic adhesive capsulitis of the shoulder, also known as Frozen Shoulder syndrome.

1 Dec 2011

Celldex launches rindopepimut Phase 3 trial in EGFRvIII-positive glioblastoma

Celldex Therapeutics, Inc. today announced that it has launched a pivotal, randomized, double-blind, controlled Phase 3 trial of rindopepimut in patients with surgically resected epidermal growth factor variant III (EGFRvIII)-positive glioblastoma, the "ACT IV Study."

1 Dec 2011

Government inspectors to lawmakers: More must be done to stop prescription of powerful psych drugs to nursing home patients

Government inspectors told lawmakers Wednesday that Medicare officials need to do more to stop doctors from prescribing powerful psychiatric drugs to nursing home patients with dementia, an unapproved practice that has flourished despite repeated government warnings.

1 Dec 2011

Chronic pain affects marital communication and ability to cope

Chronic pain suffered by one spouse can affect marital communication and influence the partner's ability to cope with a chronic pain condition, according research reported in The Journal of Pain, published by the American Pain Society.

1 Dec 2011

Majority of Californians requiring mental health treatment receive inadequate services

Nearly 2 million adults in California, about 8 percent of the population, need mental health treatment, but the majority receive no services or inadequate services, despite a state law mandating that health insurance providers include mental health treatment in their coverage options, a new report by the UCLA Center for Health Policy Research shows.

1 Dec 2011

Study presents high-resolution genome-wide p53-binding map for normal human cells

Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells. The distinct binding patterns reflect differences in the chromatin (the way DNA is packed with proteins), which may be important for understanding the function of the tumor suppressor protein in cancer cells.

1 Dec 2011

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

The most poisonous substance on Earth - already used medically in small doses to treat certain nerve disorders and facial wrinkles - could be re-engineered for an expanded role in helping millions of people with rheumatoid arthritis, asthma, psoriasis and other diseases, scientists are reporting. Their study appears in ACS' journal Biochemistry.

1 Dec 2011

Study reveals no clear advantage of one implant type over another

More than 270,000 Americans get hip replacement surgeries every year -- a number that is projected to double in the next decade as the population ages. With various options for implants, including metal-on-polyethylene, metal-on-metal and ceramic-on-ceramic, there have been questions about which kind works best.

1 Dec 2011

Even those with egg allergies should receive the flu vaccine

With the coughing, sneezing and achy flu season upon us, new recommendations say that even those with egg allergies should receive the flu vaccine.

1 Dec 2011

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

Speaking today at the plenary session of the 7th Annual European Antibody Congress in Geneva, Dr. Anat Cohen-Dayag, President and CEO of Compugen Ltd., presented Compugen's Antibody Target Discovery Platform, one of the Company's predictive discovery platforms for novel therapeutic targets.

1 Dec 2011

Medical Condition News

Health disparity tends to increase among young U.S. adults

Two studies uncover limitations in screening for hepatocellular carcinoma

Idera receives FDA notification to proceed with IMO-3100 Phase 2 clinical trial for psoriasis

AVEO, Boehringer Ingelheim enter development and manufacturing agreement for ficlatuzumab

ADVENTRX, FDA discuss ANX-188 development plans for treatment of sickle cell crisis

Positive interim data from Anthera's PEARL-SC phase 2b clinical study in systemic lupus erythematosus

Body's surveillance for cancer causing damage and response to allergies share common pathway

Insights into causes of Idiopathic Pulmonary Fibrosis

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

FDA clears Covidien's SpiderFX embolic protection device

Auxilium initiates XIAFLEX phase IIa trial in Frozen Shoulder syndrome

Celldex launches rindopepimut Phase 3 trial in EGFRvIII-positive glioblastoma

Government inspectors to lawmakers: More must be done to stop prescription of powerful psych drugs to nursing home patients

Chronic pain affects marital communication and ability to cope

Majority of Californians requiring mental health treatment receive inadequate services

Study presents high-resolution genome-wide p53-binding map for normal human cells

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

Study reveals no clear advantage of one implant type over another

Even those with egg allergies should receive the flu vaccine

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

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