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NCoR deficiency may pump up muscles and prevent diabetes

Two independent studies in the Nov. 11 issue of the journal Cell, a Cell Press publication, suggest a common way to pump up muscles and prevent diabetes. The key is a molecule required for fine-tuning metabolism by selectively and subtly modifying core metabolic programs.

11 Nov 2011

Link between physical activity, sedentary behavior and sleep in teens

Earlier research has had similar findings, but this is the first large, nationally representative study to connect physical activity, sedentary behavior and sleep in high school students, explained Kathryn Foti, M.P.H., a health scientist at the Centers for Disease Control and Prevention's (CDC) Division of Adolescent and School Health and lead author of the paper.

11 Nov 2011

Psychotherapy technique can help reduce dementia caregivers' stress

Family caregivers of people with dementia experience more burden and are at greater risk of developing depression than caregivers of people with a chronic illness. A new evidence review from the Netherlands finds that a psychotherapy technique called cognitive reframing can help reduce caregivers' stress when they are caring for loved ones with dementia.

11 Nov 2011

Provectus announces data from Phase 2 PV-10 metastatic melanoma study

Provectus Pharmaceuticals, Inc., a development-stage oncology and dermatology biopharmaceutical company, announces that data from its Phase 2 PV-10 metastatic melanoma study will be presented at the 2011 International Melanoma Congress on November 12, 2011, during the 5th Meeting of Interdisciplinary Melanoma/Skin Cancer Centres meeting.

11 Nov 2011

First large scale trial of acupuncture for prevention of xerostomia

When given alongside radiation therapy for head and neck cancer, acupuncture has shown for the first time to reduce the debilitating side effect of xerostomia, according to new research from The University of Texas MD Anderson Cancer Center and Fudan University Shanghai Cancer Center.

11 Nov 2011

New potential target to slow breast cancer tumor progression and metastasis

A new potential target to slow breast cancer tumor progression and metastasis has been identified by a team of researchers led by Dr. Richard Kremer from the Research Institute of the McGill University Health Centre.

11 Nov 2011

High-fiber diets may lower risk of heart disease, type-2 diabetes in teens

A diet high in fiber - but not necessarily one low in saturated fat or cholesterol - is tied to a lower risk of heart disease and type-2 diabetes in teenagers, according to new findings from Michigan State University.

11 Nov 2011

New unsuspected role for nuclear receptor corepressor protein

By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.

11 Nov 2011

Insights into potential causes of temporomandibular joint disorders

New findings about painful jaw problems that plague millions of Americans are leading to a better understanding of pain disorders.

11 Nov 2011

Classical DCs associated with protection against atherosclerosis

Atherosclerosis, commonly referred to as "hardening of the arteries," is a major risk factor for heart attack and stroke. The cause of atherosclerosis is not well understood but, for some time, chronic inflammatory immune responses have been implicated in driving disease pathology. Now, a new study, published online on November 10th by Cell Press from the journal Immunity, identifies a type of immune cell that is not associated with promoting disease, but with protection against atherosclerosis.

11 Nov 2011

Watson receives FDA approval for generic Kadian ANDA

Watson Pharmaceuticals, Inc. today announced that it has received approval from the United States Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for morphine sulfate extended-release capsules USP, the generic equivalent of Actavis' Kadian.

11 Nov 2011

Alcohol consumption may decrease risk of death from coronary artery disease

In a prospective, observational study of approximately 150,000 Norwegians, the investigators found that alcohol consumption was associated with a large decrease in the risk of death from coronary artery disease.

11 Nov 2011

Novartis files suit against Watson over generic Exelon

Watson Pharmaceuticals, Inc. today confirmed that its subsidiary, Watson Laboratories, Inc., filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market rivastigmine transdermal system patches, 4.6 mg/24 hr and 9.5 mg/24 hr.

11 Nov 2011

Long-range wind transport of an infectious agent may cause KD

Kawasaki Disease (KD) is a severe childhood disease that many parents, even some doctors, mistake for an inconsequential viral infection. In fact, if not diagnosed or treated in time, it can lead to irreversible heart damage. After 50 years of research, including genetic studies, scientists have been unable to pinpoint the cause of the disease.

10 Nov 2011

Researchers uncover mechanism that governs cell specialization

Researchers at then Albert Einstein College of Medicine of Yeshiva University have uncovered a mechanism that governs how cells become specialized during development.

10 Nov 2011

SNI receives NINDS grant to conduct clinical research studies on brain disorders

Swedish Neuroscience Institute (SNI) has been selected by the National Institutes of Health as the Pacific Northwest member of a national consortium of 25 neuroscience centers that will conduct clinical research studies on a variety of brain-related diseases.

10 Nov 2011

NYBC receives FDA approval for HEMACORD HPC-C cell therapy

The U.S. Food and Drug Administration today approved HEMACORD, the first licensed hematopoietic progenitor cells-cord (HPC-C) cell therapy.

10 Nov 2011

Stroke warning signs need more urgent attention

Patients who suffer stroke-like attacks can have mortality rates 20 per cent higher than the general population, new research finds, leading to calls for better stroke prevention strategies for those who experience a transient ischemic attack (TIA).

10 Nov 2011

APMA encourages 'Knock Your Socks Off' foot care campaign for people with diabetes

American Podiatric Medical Association Encourages Hispanic Health Awareness with "Knock Your Socks Off" Foot Care Campaign, Promotes Regular Foot Exams by Podiatrist to End Diabetes Complications

10 Nov 2011

ArQule, Daiichi Sankyo enter license agreement for development of new AKT inhibitor

ArQule, Inc. and Daiichi Sankyo, Co. Ltd. announced today the execution of a license agreement for the development of a new AKT inhibitor called ARQ 092, the first compound to emerge from the companies' November 2008 agreement to collaborate on research utilizing the AKIP (ArQule Kinase Inhibitor Platform) technology to generate novel, selective and potent small molecule kinase inhibitors.

10 Nov 2011