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ALS damages neurons in parts of the brain responsible for cognition and behaviour

Recently published studies by a researcher in the Faculty of Medicine & Dentistry demonstrate that ALS - known as Lou Gehrig's disease - damages neurons in parts of the brain responsible for cognition and behaviour.

17 Sep 2011

Case Western Reserve awarded $11.3M to establish gastrointestinal cancer research center

The National Cancer Institute has awarded $11.3 million to Case Western Reserve University School of Medicine to establish a center of excellence for research on gastrointestinal cancers. The funding designates the university as a Specialized Program of Research Excellence (SPORE) in Gastrointestinal (GI) Cancers - recognition extended to just one institution this year.

17 Sep 2011

Reducing levels of protein FKBP51 may yield new antidepressant therapies

Decreasing expression of a protein associated with susceptibility to depression made old mice resistant to depressive-like behavior while improving their hormonal response to stress, a study led by researchers at the University of South Florida found. The lack of this protein, FKBP51, did not adversely affect their memory, learning, or basic motor functions.

17 Sep 2011

Study finds no clear advantage of ultrasound guidance for pain relief in nerve block procedures

Using ultrasound to guide the performance of nerve blocks—in which anesthetics are directly targeted to a specific nerve or group of nerves—has contributed to the increased use of regional anesthesia.

17 Sep 2011

AHRQ: Hospital readmissions comparatively higher among black COPD patients

For patients age 40 and over with chronic obstructive pulmonary disease (COPD), hospital readmissions within 30 days of initial treatment were 30 percent higher among blacks than Hispanics or Asians and Pacific Islanders and about 9 percent higher than whites in 2008, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

17 Sep 2011

New insight into how nervous system regulates immunity

Scientists have identified a surprising new role for a new type of T cell in the immune system: some of them can be activated by nerves to make a neurotransmitter (acetylcholine) that blocks inflammation. The discovery of these T cells is novel and suggests that it may be possible to treat inflammation and autoimmune diseases by targeting the nerves and the T cells. The study was published this week in Science.

17 Sep 2011

Researchers show how protein fortilin promotes growth of cancer cells

Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of Texas Medical Branch may lead to treatments for a range of cancers and atherosclerosis, which p53 also helps prevent, and appears in the current print issue of the Journal of Biological Chemistry.

17 Sep 2011

Household income level not associated with intellectual disability or ASD, finds new study

New research from the University of Utah in collaboration with the Utah Department of Health (UDOH) shows that the presence or absence of intellectual disability (ID) and autism spectrum disorders (ASD) varies with risk factors such as gender, parental age, maternal ethnicity, and maternal level of education.

17 Sep 2011

Multiple abstracts on QNEXA presented at 47th EASD

VIVUS, Inc. today announced that multiple abstracts were presented at the 47th European Association for the Study of Diabetes (EASD) Annual Meeting in Lisbon, Portugal. The presentations highlighted the long-term beneficial effects of QNEXA treatment in metabolically-impaired patients with prediabetes, diabetes, and metabolic syndrome.

17 Sep 2011

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

Thanks to greater awareness, earlier detection and improving therapeutic agents, people with cancer are living longer than ever before. One of the consequences of living longer is the symptom burden of cancer survivorship, which may have a substantial impact on quality of life for many survivors. One such burden is the pain syndromes resulting from cancer treatments.

17 Sep 2011

Venus Williams withdraws from US Open due to Sjogren syndrome

Sjogren syndrome was in the news recently when tennis player, Venus Williams, was forced to withdraw form the US Open tennis tournament due to symptoms from the disease.

17 Sep 2011

Vesicular stomatitis virus kills cancer cells

In a new project, researchers from LIFE - the Faculty of Life Sciences at the University of Copenhagen - document that the vesicular stomatitis virus (VSV) plays a previously unknown dual role in the prevention of a number of cancers. The new findings show that the virus both kills cancer cells and stops the expression of the molecules which certain types of cancer cells produce to hide from the immune system.

17 Sep 2011

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

Two newer drugs used to treat Type 2 diabetes could be linked to a significantly increased risk of developing pancreatitis and pancreatic cancer, and one could also be linked to an increased risk of thyroid cancer, according to a new UCLA study.

17 Sep 2011

Adult stem cells hold hope for treatment of lupus

With a patient's own adult stem cells, there is new hope for the intractable autoimmune disease lupus - systemic lupus erythematosus (SLE) - which is difficult to cure.

17 Sep 2011

DryDiapersPlus joins Unique Wellness and BIOTX to provide incontinence products

DryDiapersPlus is excited to announce that they have joined with Unique Wellness and BIOTX Ltd to provide world-class incontinence products for their customers.

16 Sep 2011

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from an investigational Phase 3b clinical study in which the addition of ONGLYZA (saxagliptin) 5 mg to ongoing insulin therapy (with or without metformin) maintained reductions of blood sugar levels (glycosylated hemoglobin levels, or HbA1c) in adult patients with type 2 diabetes compared to the addition of placebo (with or without metformin) from 24 to 52 weeks.

16 Sep 2011

Policies needed to prepare individuals, society for earlier diagnosis and high risk of Alzheimer's

The changing tide of Alzheimer's diagnosis presents new challenges to the public, physicians and lawmakers: if you could find out your Alzheimer's risk, would you want to know? How should doctors tell you your risk? And what does it mean for the many newly diagnosed Americans still in the workplace?

16 Sep 2011

Linagliptin demonstrates durable reductions in blood glucose for T2D adults

Boehringer Ingelheim and Eli Lilly and Company today announced results of a 102 week Phase III study for linagliptin, which show meaningful and durable reductions in blood glucose for adults with type 2 diabetes.

16 Sep 2011

Combination of prasugrel plus ASA can treat acute coronary syndrome

In order to better prevent blood clots, the drugs clopidogrel or prasugrel can be prescribed to patients with acute ischaemia of the heart muscle, in addition to acetylsalicylic acid.

16 Sep 2011

New collaboration reinforces Sanofi's translational discovery platform for retinal diseases

The Max Planck Society (Max-Planck-Gesellschaft), Germany's leading basic research organization, announced today that it has signed with Fovea Pharmaceuticals, the Ophthalmology Division of Sanofi, a research collaboration and license agreement to identify and develop innovative solutions for restoring vision in patients suffering from diseases affecting the retina.

16 Sep 2011

Medical Condition News

ALS damages neurons in parts of the brain responsible for cognition and behaviour

Case Western Reserve awarded $11.3M to establish gastrointestinal cancer research center

Reducing levels of protein FKBP51 may yield new antidepressant therapies

Study finds no clear advantage of ultrasound guidance for pain relief in nerve block procedures

AHRQ: Hospital readmissions comparatively higher among black COPD patients

New insight into how nervous system regulates immunity

Researchers show how protein fortilin promotes growth of cancer cells

Household income level not associated with intellectual disability or ASD, finds new study

Multiple abstracts on QNEXA presented at 47th EASD

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

Venus Williams withdraws from US Open due to Sjogren syndrome

Vesicular stomatitis virus kills cancer cells

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

Adult stem cells hold hope for treatment of lupus

DryDiapersPlus joins Unique Wellness and BIOTX to provide incontinence products

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Policies needed to prepare individuals, society for earlier diagnosis and high risk of Alzheimer's

Linagliptin demonstrates durable reductions in blood glucose for T2D adults

Combination of prasugrel plus ASA can treat acute coronary syndrome

New collaboration reinforces Sanofi's translational discovery platform for retinal diseases

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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