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Positive topline data from 4SC's resminostat Phase II trial on Hodgkin's Lymphoma

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune diseases and cancer, today announced positive topline data from its Phase II SAPHIRE trial with resminostat, its oral pan HDAC inhibitor, in patients with relapsed/refractory Hodgkin's Lymphoma.

6 Sep 2011

Biologists reveal why men's ring fingers are longer than their index fingers

Biologists at the University of Florida have found a reason why men's ring fingers are generally longer than their index fingers - and why the reverse usually holds true for women.

6 Sep 2011

Researchers reveal mechanism behind how cells communicate

Cell communication is essential for the development of any organism. Scientists know that cells have the power to "talk" to one another, sending signals through their membranes in order to "discuss" what kind of cell they will ultimately become - whether a neuron or a hair, bone, or muscle. And because cells continuously multiply, it's easy to imagine a cacophony of communication.

6 Sep 2011

AMT, NIH enter exclusive license agreement for use of AAV5-based gene therapy vectors

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, today announced that it has entered into an exclusive license agreement with the US National Institutes of Health (NIH) for use of adeno-associated virus serotype 5 (AAV5)-based gene therapy vectors for liver and brain indications.

6 Sep 2011

Study: No big shift toward higher fatal heart attack rates after menopause in women

Contradicting the long-held medical belief that the risk of cardiovascular death for women spikes sharply after menopause, new research from Johns Hopkins suggests instead that heart disease mortality rates in women progress at a constant rate as they age.

6 Sep 2011

Lilly, QIAGEN partner to develop and commercialize companion diagnostic for JAK2 V617F

QIAGEN today announced that it has entered into a partnership with Eli Lilly and Company for the development, manufacturing and commercialization of a molecular companion diagnostic for an early stage investigational compound currently being developed by Lilly. Financial terms of the agreement were not disclosed.

From QIAGEN Manchester Limited 6 Sep 2011

Psychogenic non-epileptic seizures may go undiagnosed for longer in veterans

Psychogenic non-epileptic seizures may go undiagnosed for much longer in veterans compared to civilians, according to a new study published in the September 6, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

6 Sep 2011

Chondroitin sulfate decreases pain and improves hand function in patients with OA

New research shows that chondroitin sulfate significantly decreased pain and improved hand function in patients with osteoarthritis (OA) of the hand compared with those in the placebo group. Results of the clinical trial available today in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR), also report that chondroitin sulfate improves grip strength and relieves morning stiffness.

6 Sep 2011

Exposure to phthalates during pregnancy may increase risk of developmental problems in children

A newly published study by researchers at Columbia University's Mailman School of Public Health heightens concerns over the potential health effects on children of a group of ubiquitous chemicals known as phthalates.

6 Sep 2011

Moderate to severe cognitive impairment has impact on life expectancy

Cognitive impairment, even when detected at an early, mild stage, is a significant predictor of decreased life expectancy.

6 Sep 2011

BioAlliance Pharma announces oral communication of Livatag Phase II trial results on liver cancer

BioAlliance Pharma SA, a company dedicated to specialty and orphan oncology products, today announces oral communication of the Phase II clinical trial results of its orphan product Livatag at the annual congress of ILCA, the only international organization devoted exclusively to liver cancer research with participation of worldwide best specialists.

6 Sep 2011

Cancer cells with specific genetic defect extra susceptible to therapy that damages DNA

Using a strategy based on treating cancer cells that carry a specific genetic signature - hyper-expression of the protein Myc - with therapy that affects the stability of the cell's DNA, more effective results can be achieved.

5 Sep 2011

Mesoblast receives EMA clearance to initiate Revascor Phase 2 trial for heart attacks

Global regenerative medicine company, Mesoblast Limited, today announced that it had received clearance from the European Medicines Agency (EMA) to begin a 225-patient multi-center Phase 2 clinical trial in Europe for its lead cardiovascular product Revascor(TM) in conjunction with angioplasty and stent procedures to prevent heart failure after a major heart attack.

5 Sep 2011

Study sheds new light on the state of Europe's mental and neurological health

A major landmark study released today by the European College of Neuropsychopharmacology (ECNP) sheds new light on the state of Europe's mental and neurological health.

5 Sep 2011

Asbestos related cancer risk rises after home renovations: Study

A third wave of asbestos-related cancers is emerging as the rate of malignant mesothelioma caused by exposure to asbestos during home renovations increases dramatically, according to new research.

5 Sep 2011

Autism diagnosis by brain scan a possibility

A team of Stanford scientists have found that the brains of autistic children have a distinctive topography and could be captured using new imaging techniques. This could someday create a template for the autistic brain that could be used to diagnose kids at a very early age they claim.

5 Sep 2011

Stroke in the young on the rise: Study

A new study has revealed that more children and young adults in the U.S. are having strokes. Researchers speculate that unhealthy lifestyles could be a likely contributor.

5 Sep 2011

Researchers discover gene mutation linked with lymphoedema, leukaemia

Researchers have discovered a gene that when mutated can cause lymphoedema (swollen limbs due to a failure of the lymph system), immune abnormalities, deafness and leukaemia.

5 Sep 2011

Scientists purify PARP protein that shows promise against breast, ovarian cancers

CANCER RESEARCH UK scientists have succeeded in purifying a protein found in bacteria that could reveal new drug targets for inherited breast and ovarian cancers - and other cancers linked to DNA repair faults.

5 Sep 2011

Teenagers use medicines frequently without receiving targeted information about risks and benefits

A large proportion of teenagers regularly and frequently take some form of medication without receiving targeted information about the risks and benefits, according to a review of current research, to be presented at the annual congress of the International Pharmaceutical Federation.

5 Sep 2011

Medical Condition News

Positive topline data from 4SC's resminostat Phase II trial on Hodgkin's Lymphoma

Biologists reveal why men's ring fingers are longer than their index fingers

Researchers reveal mechanism behind how cells communicate

AMT, NIH enter exclusive license agreement for use of AAV5-based gene therapy vectors

Study: No big shift toward higher fatal heart attack rates after menopause in women

Lilly, QIAGEN partner to develop and commercialize companion diagnostic for JAK2 V617F

Psychogenic non-epileptic seizures may go undiagnosed for longer in veterans

Chondroitin sulfate decreases pain and improves hand function in patients with OA

Exposure to phthalates during pregnancy may increase risk of developmental problems in children

Moderate to severe cognitive impairment has impact on life expectancy

BioAlliance Pharma announces oral communication of Livatag Phase II trial results on liver cancer

Cancer cells with specific genetic defect extra susceptible to therapy that damages DNA

Mesoblast receives EMA clearance to initiate Revascor Phase 2 trial for heart attacks

Study sheds new light on the state of Europe's mental and neurological health

Asbestos related cancer risk rises after home renovations: Study

Autism diagnosis by brain scan a possibility

Stroke in the young on the rise: Study

Researchers discover gene mutation linked with lymphoedema, leukaemia

Scientists purify PARP protein that shows promise against breast, ovarian cancers

Teenagers use medicines frequently without receiving targeted information about risks and benefits

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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