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Human kinome RNAi screening performed using Roche’s xCELLigence MP Instrument

RNA interference studies are a powerful technology for high-throughput screening. However, endpoint analyses only provide a snapshot of the analyzed cellular phenotype, as it is not possible to measure developmental changes over time.

29 Jul 2011

South Asians more likely to add organ-hugging fat linked with cardiovascular disease

It's not fair, but it's true. A new study by researchers at McMaster University has found that some ethnic groups are more likely to be adding dangerous fat onto their internal organs like their liver when they gain weight, while others just add it to their waistline.

29 Jul 2011

Scientists discover gene pattern that distinguishes severe from less aggressive bone cancer

A new University of Minnesota discovery may help bone cancer patients fight their disease more effectively, according to new research published in the September issue of Bone.

29 Jul 2011

Studies reveal new set of mutations linked with head and neck cancer

Powerful new technologies that zoom in on the connections between human genes and diseases have illuminated the landscape of cancer, singling out changes in tumor DNA that drive the development of certain types of malignancies such as melanoma or ovarian cancer.

29 Jul 2011

Veterinary medicine students more likely to struggle with depression

Veterinary medicine students are more likely to struggle with depression than human medicine students, undergraduate students and the general population, according to several recent collaborative studies from Kansas State University researchers.

29 Jul 2011

Positive data from BioMarin's MOR-100 Phase 1/2 extension study on Morquio syndrome

BioMarin Pharmaceutical Inc. today announced an update on the GALNS Phase 1/2 extension study (MOR-100) in which patients have continued treatment on an ongoing basis.

29 Jul 2011

Customized surfaces help reveal protein clumping process linked with Alzheimer's, diabetes

When normal proteins form protein clumps in the body, then alarm bells start ringing. Such clumps, called "amyloids," are closely associated with Alzheimer's disease and type 2 diabetes, formerly called adult-onset diabetes.

29 Jul 2011

Hospice services improve quality of care and support for dementia patients

Hospice services substantially improved the provision of care and support for nursing home patients dying of dementia and their families, according to an analysis of survey responses from hundreds of bereaved family members.

29 Jul 2011

NanoString introduces new assay for leukemia fusion gene analysis

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced the availability of a comprehensive multiplexed assay for the simple and cost-effective analysis of fusion genes linked to leukemia.

From NanoString Technologies 29 Jul 2011

WSU professor receives NIH grant for non-alcoholic fatty liver disease research

Kezhong Zhang, Ph.D., assistant professor of molecular medicine and genetics and of immunology and microbiology in the School of Medicine at Wayne State University, was awarded $1.7 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health to explore how molecular elements in the body regulate the development of non-alcoholic fatty liver disease.

29 Jul 2011

Grapes help protect skin cells from sun's UV radiation

Some compounds found in grapes help to protect skin cells from the sun's ultraviolet radiation, according to a study by researchers from the University of Barcelona and the CSIC.

29 Jul 2011

'Systems biology' study of breast cancer

Using a "systems biology" approach - which focuses on understanding the complex relationships between biological systems - to look under the hood of an aggressive form of breast cancer, researchers for the first time have identified a set of proteins in the blood that change in abundance long before the cancer is clinically detectable.

29 Jul 2011

Houston-based Mattress Firm commits to support pancreatic cancer research

Mattress Firm, a leading specialty mattress retailer with more than 720 stores nationwide, is committed to supporting the fight against pancreatic cancer by raising funds for clinical trials through the Translational Genomics Research Institute (TGen) globalCure initiative.

29 Jul 2011

Bone fluoride levels are not associated with osteosarcoma: Study

A new study in the Journal of Dental Research finds bone fluoride levels are not associated with osteosarcoma, a rare bone cancer more prevalent in males.

29 Jul 2011

Conference to discuss latest advances in brain tumours by non-surgical means, space science

The latest advances in the treatment of brain tumours by non-surgical means, space science and non-fossil fuel energy generation, are among the topics being discussed by over 500 international scientists at Queen's University this week.

29 Jul 2011

Expert offers air quality control tips

A mold count of more than 50,000 has triggered an alert for dangerous air quality throughout the Midwest . The Midwest experienced a record-breaking winter for snow, and is again setting new records for heat and rain.

29 Jul 2011

Book examines impact of new racial science

In 2005, the Food and Drug Administration approved a drug called BiDil as a therapy for heart failure specifically for African-American patients, claiming in a press release that this was a step toward personalized medicine.

29 Jul 2011

Combination drug regimen safe and effective for renal transplant patients

For the thousands of patients who receive kidney transplants in the United States each year, preventing organ rejection without compromising other aspects of health requires a delicate balance of medications.

29 Jul 2011

High fructose corn syrup consumption may promote heart disease

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that adults who consumed high fructose corn syrup for two weeks as 25 percent of their daily calorie requirement had increased blood levels of cholesterol and triglycerides, which have been shown to be indicators of increased risk for heart disease.

29 Jul 2011

Ivabradine effective in reducing risk of cardiac fibrosis, diastolic heart failure

The findings of a Montreal Heart Institute (MHI) study published in the scientific journal Cardiology suggest that ivabradine, a heart rate reduction medication, is also effective in reducing the risk of diastolic heart failure and cardiac fibrosis.

29 Jul 2011