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Kowa announces data of LIVALO vs. Crestor on pharmacodynamics of warfarin

Kowa Pharmaceuticals America, Inc. today announced data assessing the effect of LIVALO (pitavastatin) compared with Crestor (rosuvastatin) on steady-state pharmacodynamics (PD) of warfarin by measuring international normalized ratio (INR) in healthy adult subjects.

14 Feb 2012

New light on treatment targets for potentially life-threatening cardiac arrhythmia conditions

That flutter in your heart may have more to do with the movement of sodium ions than the glance of a certain someone across a crowded room.

14 Feb 2012

'Targeted' drugs may be effective against lung and colorectal tumors driven by novel gene abnormalities

Novel gene abnormalities discovered in a subpopulation of lung and colorectal tumors could potentially identify patients with a good chance of responding to highly specific "targeted" drugs already in use for treating other cancers, scientists report.

14 Feb 2012

Healthy, loving relationship is good for the heart

Being involved in a healthy, loving relationship is good for the heart, says Vanderbilt Heart and Vascular Institute cardiologist Julie Damp, M.D.

14 Feb 2012

Machine-learning methods show that patients with severe brain injury could communicate accurately

Only by employing complex machine-learning techniques to decipher repeated advanced brain scans were researchers at NewYork-Presbyterian/Weill Cornell able to provide evidence that a patient with a severe brain injury could, in her way, communicate accurately.

14 Feb 2012

Prevention and treatment options are improving long-term outcomes for heart failure

"Despite the increasing number of people affected, the prognosis for patients with heart failure has steadily improved," said Gregg C. Fonarow, M.D, chairman of American Heart Association Hospital Accreditation Science Committee and professor of cardiovascular medicine of the University of California, Los Angeles.

14 Feb 2012

Switching from calorie-laden beverages to water can help lose weight

Making a simple substitution of water or diet soft drinks for drinks with calories can help people lose 4 to 5 pounds, a new University of North Carolina at Chapel Hill study shows.

14 Feb 2012

Radiation treatment transforms breast cancer stem cells into new iBCSCs

Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don't respond well to chemotherapy.

14 Feb 2012

Second and third generation Mexican-Americans more likely to be obese

A University of South Carolina study shows that Mexican-American youth gain pounds as they move away from the dietary habits of their native country, a move that is putting them at risk for serious health problems.

14 Feb 2012

Ensysce announces latest data on delivery platform for therapeutic siRNA

Ensysce Biosciences Inc. announced today the publication of their latest data on their delivery platform for short interfering RNA (siRNA) for therapeutic purposes in the journal Materials.

14 Feb 2012

Stress protein effectively activates replication of HBV in liver cells

People who have received a donor organ need lifelong immunosuppressant drugs to keep their immune system from attacking the foreign tissue. However, with a suppressed immune system, many infectious agents turn into a threat. Infections such as with human cytomegalovirus and a certain type of human polyomavirus frequently cause complications in transplant recipients.

14 Feb 2012

Merck Serono, Mendor sign blood glucose meter distribution agreement

Mendor, the Finnish diabetes technology company, continues its rapid growth and is excited to announce yet another international partnership - now opening the United Kingdom for its innovative products. Mendor has just signed a distribution agreement with a leading pharmaceutical company in the Diabetes field Merck Serono, covering the United Kingdom diabetes market.

14 Feb 2012

Knee replacements double in 10 years, study says

More than 4 million Americans over 50 have artificial knees, according to a new study. ... "These data are sobering because we didn't know what an army of people we've created over the last decade," said study author Elena Losina, co-director of the Orthopedics and Arthritis Center for Outcomes Research at Harvard's Brigham and Women's Hospital. ... Artificial knees also wear out after a period of time, so as the operations are increasingly done on younger Americans, many will live long enough to almost certainly need a second or even third knee replacement.

14 Feb 2012

U of A professor receives $542,000 from NSERC for drinking water research

Water is something people can't live without, that's why it's important that Xing Fang Li finds out what is in our tap water that may pose a disease risk. The researcher from the Faculty of Medicine & Dentistry at the University of Alberta just received $542,000 from the Natural Sciences and Engineering Research Council of Canada for drinking water research.

14 Feb 2012

IBD may disrupt school functioning in children

Children with inflammatory bowel disease (IBD) may have difficulty functioning in school, particularly because their tendency to internalize problems can impact attendance.

14 Feb 2012

Karo Bio decides to discontinue development program for eprotirome

Karo Bio AB (publ) has decided to discontinue the development program for eprotirome after an animal study has demonstrated unwanted effects following long-term exposure. The planned spin-off of the preclinical part of operations will not proceed.

14 Feb 2012

Fresh insights into cell division could help scientists develop cancer drugs

Fresh insights into how our cells multiply could help scientists develop drugs to treat cancer. Researchers have gained better understanding of the workings of two key proteins that control cell division. This process must be carried out accurately to keep cells healthy, and when it goes out of control, it can lead to cancer.

14 Feb 2012

New potential therapy for Huntington disease

Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, says the lead researcher.

14 Feb 2012

Surgery causes musculoskeletal alterations in breast cancer patients

A research study conducted at the University of Granada -and published in the prestigious American Journal of Physical Medicine and Rehabilitation-has revealed that the surgery performed on breast cancer patients causes musculoskeletal alterations.

14 Feb 2012

Fair trade agreement between E.U., India could impede access to medicine for world's poor

"Current negotiations on a free trade agreement (FTA) between the European Union and India are causing serious concern in many quarters over future access to cheap generic medicines used to treat some of the world's great public health threats: HIV, tuberculosis and malaria, and also cancer," Philippe Douste-Blazy, U.N. special adviser on innovative financing for development and chair of UNITAID, and Denis Broun, executive director of UNITAID, write in this post in the Guardian's "Poverty Matters Blog."

14 Feb 2012