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The role of geroscience in understanding Alzheimer’s Disease

For more than 30 years, researchers have identified and quantified genetic and lifestyle factors for Alzheimer's Disease (AD) and other dementias. Despite extensive research, the fundamental mechanisms behind these neurodegenerative diseases are still not fully understood, and effective management of AD is taking longer than expected.

10 Oct 2024

Could heparin offer new hope in the fight against dementia?

Heparin therapy delays Alzheimer's diagnosis by one to two years, offering potential insights into new protective treatments. Large-scale health records show a promising association between the anticoagulant and delayed dementia onset.

10 Oct 2024

Breast cancer mortality plummets by 44%, but alarming racial gaps persist

The latest American Cancer Society report reveals a 44% decline in breast cancer mortality since 1989, but racial disparities remain, with underserved populations seeing little progress. Increased screening and access to treatment are critical for future reductions.

9 Oct 2024

Pitt researchers validate comprehensive blood test for Alzheimer's biomarkers

University of Pittsburgh scientists independently validated a new blood test platform that can simultaneously measure more than a hundred biomarkers of Alzheimer's disease.

9 Oct 2024

CRISPR-based rapid molecular diagnostic developed for two forms of leukemia

Researchers at Dana-Farber Cancer Institute have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene fusions.

9 Oct 2024

Study illuminates the origin and progression of bladder cancer

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center.

9 Oct 2024

Dual immunotherapy plus chemotherapy shows promise for specific lung cancer patients

Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more likely to benefit from adding the immunotherapy tremelimumab to a combination of durvalumab plus chemotherapy to overcome treatment resistance typically seen in this patient population.

9 Oct 2024

New review explores Zika virus as a potential treatment for brain cancer

A new review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Zika virus and brain cancer: Can Zika be an effective treatment for brain cancer? A systematic review."

9 Oct 2024

Novel gene therapy holds potential in treating patients with epilepsy

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) are working on a therapy that holds potential in treating patients with epilepsy, a neurological disorder defined by recurring seizures due to abnormal brain activity.

9 Oct 2024

Heavy alcohol consumption associated with increased risk of cardiac arrhythmias

Researchers at LMU University Hospital find cardiac arrhythmias in partygoers who had drunk a lot of alcohol.

9 Oct 2024

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using advanced techniques like CRISPR interference to identify TE-related risk genes.

9 Oct 2024

Groundbreaking study challenges treatment protocols for glioblastoma in older adults

A groundbreaking study led by Dr Monika E. Hegi, MD, PhD and European Organisation for Research and Treatment of Cancer (EORTC) headquarters team (Felix Oppong Msc, Dr Thierry Gorlia, PhD) reveals that older adults glioblastoma patients with truly unmethylated MGMT promoter do not benefit from temozolomide (TMZ) treatment, challenging current treatment protocols and paving the way for more personalised therapies.

9 Oct 2024

COVID-19 survivors at greater risk for heart attack, stroke and death

A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California.

9 Oct 2024

Impaired creatine metabolism identified in people with type 2 diabetes

A new study from Karolinska Institutet, published in Science Translational Medicine, shows that people with type 2 diabetes have lower levels of the protein that breaks down and converts creatine in the muscles.

9 Oct 2024

Research shows link between multiple sclerosis to increased risk of certain cancers

A new study has found some cancers to be slightly more frequent in people with multiple sclerosis (MS) than in people without MS.

9 Oct 2024

New research offers hope for treating metabolic dysfunction-associated liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) — previously known as "non-alcoholic fatty liver disease" — affects about 25% of the global population.

9 Oct 2024

New study links persistent SARS-CoV-2 proteins to long COVID symptoms

Brigham researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.

9 Oct 2024

COVID-19 found to increase heart attack and stroke risks

An analysis of data in the UK Biobank has found that COVID-19 infection may increase the risk of heart attack, stroke and death from any cause for up to three years for people with and without cardiovascular disease, according to new research published today in the American Heart Association's peer-reviewed journal Arteriosclerosis, Thrombosis and Vascular Biology (ATVB).

9 Oct 2024

NCCN and LACOG collaborate to enhance cancer care in South America

The National Comprehensive Cancer Network® (NCCN®)-;an alliance of leading cancer centers in the United States-;announces a renewed collaboration with the Latin American Cooperative Oncology Group (LACOG) to improve cancer outcomes in South America.

9 Oct 2024